Báo cáo y học: "Association of ENPP1 gene polymorphisms with hand osteoarthritis in a Chuvasha population" doc

... Russian Federation. The extent of osteoarthritis was determined by analyzing plain hand radiographs. The outcome of a principal component analysis of osteoarthritis scores of a total of 28 joints ... with advanced OA. In contrast to general- ized arterial calcification of infancy, in which hydroxyapatite crystals are formed, calcium pyrophosphate dihydrate crystal...

Ngày tải lên: 09/08/2014, 06:23

... was obtained from NEN Life Science Products (Paris, France). Calnexin rabbit polyclonal antibody (SPA-860), calreticulin rabbit polyclonal antibody (SPA-600), BiP rabbit polyclo- nal antibody (SPA ... for 2 min at 10 000 g.The supernatant was immunoprecipitated with mAb A1 0. Samples were analyzed by SDS/PAGE after reduction: (A) SDS/PAGE analysis; (B) quantification using a Phosphorimage...

Ngày tải lên: 31/03/2014, 08:20

... oste- oarthritis. Nat Genet 2007, 39:529-533. 6. Kizawa H, Kou I, Iida A, Sudo A, Miyamoto Y, Fukuda A, Mabuchi A, Kotani A, Kawakami A, Yamamoto S, Uchida A, Nakamura K, Notoya K, Nakamura Y, Ikegawa ... Fujioka M, Sudo A, Uchida A, Yamamoto S, Ozaki K, Takigawa M, Tanaka T, Nakamura Y, Jiang Q, Ikegawa S: A functional polymorphism in the 5' UTR of GDF5 is associated...

Ngày tải lên: 09/08/2014, 10:23

... seen in children. A coraco id fracture can be isolated or associated with an injury complex, including any of acromiclavicular disruption, clavicular fracture, acromial fracture, scapu- lar spine ... the patient for publication of this case and any accompanying images. A copy of the written consent is available for review by the Editor -in- Chief of this journal. List of abb...

Ngày tải lên: 20/06/2014, 04:20

... process associated with a true acromioclavicular joint dislocation in a 12 year old boy, with no separation of the epiphyseal plate, as one might expect. Treatment also remains controversial. Our patient underwent ... joint dislocation is a very rare injury in a child below the age of thirteen [4]. We report an interesting case of fracture of the coracoid process assoc...

Ngày tải lên: 20/06/2014, 07:20

... were initially selected for investigation because they had all been associated with RA in the Japanese population on single-point analysis, because the SNPs formed a haplotype associated with RA and ... reported and replicated with rheumatoid arthritis (RA) in Japanese populations. The aim of this study was to investigate association of the FCRL3 gene with RA in UK subje...

Ngày tải lên: 09/08/2014, 08:22

... Kawaguchi 1 , Manabu Kawamoto 1 , Yasuhiro Katsumata 1 , Kae Takagi 1 , Ayako Nakajima 1 , Tadayuki Mitamura 2 , Akio Mimori 3 , Masako Hara 1 and Naoyuki Kamatani 1 1 Institute of Rheumatology, Tokyo ... isoniazid and rifampicin-induced hepatotoxicity. Int J Tuberc Lung Dis 2000, 4:256-261. 15. Tanaka E, Taniguchi A, Urano W, Nakajima H, Matsuda Y, Kitamura Y, Saito M, Yamanaka H, Sa...

Ngày tải lên: 09/08/2014, 10:20

... was as homogeneous as that in the 24CAs samples, vali- dating our stratification of patients by 24CAs allele. A similar pattern was also observed in healthy individuals, although a statistical ... (data not shown) and that CD154 was associated with RA independently of the presence of DR4 (Table 1). The influence of sex in the associ- ated variables was analyzed by using a...

Ngày tải lên: 09/08/2014, 10:21

... assessed by medical records and/or self-reported questionnaire and each case was validated by cardiac ultrasound and/or electrocardiographic examinations or by coronary angiography. Table 1: Patient ... likely represent cases of secondary hyperlipidaemia did not alter our findings. A possible gene- to -gene interaction between PPARδ +294T/C and Apolipoprotein E (ApoE) was analy...

Ngày tải lên: 31/10/2012, 17:03

... the starvation period gives rise to a notable initial increase in the activity of the lower part of glycolysis (E 2 ). This effect is paralleled by an increase in the activity of ethanol formation ... maximization of the flux rate through a metabolic pathway at any time as a (short- term) goal of genetic regulation [23,24]. Dealing with the evolutionary optimization of...

Ngày tải lên: 17/03/2014, 10:20