Báo cáo y học: "κ The TRAF6-NFκB signaling pathway in autoimmunity: not just inflammation" ppsx

... actively maintained in the thymus [2]. During this process, a repertoire of T cells restricted to self-MHC displayed by the thymic cortical epithelial cells (cTECs) is selected in each individual. In addition, ... periphery and in the thymus, the immune system must balance antigen presentation and pro- inflammatory outcomes in the periphery in response to pathogens and o...

Ngày tải lên: 09/08/2014, 06:23

... inter- viewer-assisted self-rating scale, rendering it practical for use in everyday practice. According to the developers, the instrument can accurately and reliably identify symptoms of anxiety in older people ... analysis was performed. Reliability Internal consistency and reproducibility were measured as part of the reliability testing of the translated tool [28]. Internal con...

Ngày tải lên: 08/08/2014, 23:21

... basis for the importance of gene order in the globin locus is not entirely clear, it is in agreement with the hypothesis that t he genes in the globin locus are competitively regulated by the LCR ... structure in the globin locus. For example, it would be interesting to examine t he binding of chromatin components and transcription factors during the cell cycle in er...

Ngày tải lên: 18/03/2014, 01:20

... c-Jun N-terminal kinase signaling in Stat3 tran- scriptional activity induced by the Src oncoprotein. Mol Cell Biol 19, 7519–7528. 19 Yin F, Wang YY, Du JH, Li C, Lu ZZ, Han C & Zhang YY (2006) ... required for the production of many cytokines in a wide variety of cells [21–23]. The gp130 ⁄ STAT3 signaling pathway mediated b-AR-induced ANF expression b-AR-induced cardiac r...

Ngày tải lên: 23/03/2014, 07:20

... cysteine, and glycine, via two ATP-con suming s teps involving c-g lut- amylcysteine synthetase ( cGCS) and glutathione synthetase. The other constitutes a recycling system involving GR which reduces ... contains no cysteine. Protamine, which is replaced for hitstone via transit proteins during spermio- genesis, is rich in both arginine and cysteine. The cysteine sulfhydryls in protam...

Ngày tải lên: 17/03/2014, 17:20

... bridge with the carboxyl group of the a-aminoadipoyl- side-chain of penicillin N (1), with arginines 74 and 75 apparently playing a less important role in side-chain binding. Taken together, the results ... type of mutant, represented by arginines 306 and 307, are located in the C-terminus. They appear to modulate the activity of the C-terminus, which encloses the DAOCS acti...

Ngày tải lên: 18/03/2014, 01:20

... eosin and hematoxylin staining of the tissue was not inter- preted as being significant by two independent patholo- gists. The other eosinophil granules such as ECP [10] and EDN [ 11] are not ... identify eosinophils in the gastrointestinal tract. Further research is necessary to identify the triggers for eosinophilia in L-HES and the application of the novel monoclonal an...

Ngày tải lên: 08/08/2014, 21:20

... only 68 psychiatrists serving a population of approximately 34 million. Less than half of them are involved in active clinical work, and they mainly practice in the major urban areas meaning that ... study and was involved in drafting the manuscript and revising it critically for intellectual content. LIK participated in acquisition, analysis and interpretation of data and was inv...

Ngày tải lên: 08/08/2014, 23:21

... an important role in this regard. The positive impact of psy- chotherapy in psychopathy was assessed in a meta-analy- sis by Salekin et al. [65]. They analysed 42 interventional studies for individuals ... while observing it being executed by another) was central in defining theories on neural pathways of empa- thy [11]. Firstly, this observation was extrapolated to hypothesise that...

Ngày tải lên: 08/08/2014, 23:21