... c-Jun N-terminal kinase signaling in Stat3 tran-scriptional activity induced by the Src oncoprotein. MolCell Biol 19, 7519–7528.19 Yin F, Wang YY, Du JH, Li C, Lu ZZ, Han C &Zhang YY (2006) ... requiredfor the production of many cytokines in a wide varietyof cells [21–23]. The gp130⁄STAT3 signaling pathway mediatedb-AR-induced ANF expressionb-AR-induced cardiac remodeling is closely linked ... secreted cytokines, particularly the gp130 family cytokines, might contribute to the delayedSTAT3 activation. Blockade of the gp130 receptorusing neutralizing antibody to gp130 markedlyinhibited...