Báo cáo y học: "ADAMTS proteinases: a multi-domain, multi-functional family with roles in extracellular matrix turnover and arthritis" pdf
... defined in the MEROPS database [5,6] and are structurally and evolutionarily related to the ADAM (a disintegrin and metalloproteinase; also part of the adamalysin subfamily) enzymes and, more distantly, ... representation of the minimal domain organisation of matrix metalloproteinase (MMP), ADAM (a disintegrin and metalloproteinase) and ADAMTS (a disintegrin and metallopro...
Ngày tải lên: 09/08/2014, 06:23
... Acad Sci USA 2006; 103(39): 14584-14589. 16. Yamaguchi H, Sasaki K, Satomi Y, Shimbara T, Kageyama H, Mondal MS, Toshinai K, Date Y, Gonzalez LJ, Shioda S, Takao T, Nakazato M, Minamino N. Peptidomic ... Chakraborty TR, Tkalych O, Nanno D, Garcia AL, Devi LA, Salton SR. Quantification of Vgf- and pro-SAAS-derived pep- tides in endocrine tissues and the brain, and their regulati...
Ngày tải lên: 03/11/2012, 10:52
... membrane was treated with a rabbit anti-iNOS polyclonal antibody or rabbit anti-PKC polyclonal antibody at 1 : 1000 dilution and anti-(rabbit IgG) Ig horseradish peroxidase conjugated antibody at 1 ... [27]. Nitrite diazotiates the aryl amine, and then the diazotiated product forms an azochromophore by coupling with naphthyl-ethylenediamine. Absorbance was measured at 550 nm in a...
Ngày tải lên: 22/02/2014, 04:20
Báo cáo Y học: Dystrobrevin requires a dystrophin-binding domain to function in Caenorhabditis elegans doc
... 4. Yeast two-hybrid assay. A plate containing SD media minus leucin, t ryp tophan and histidine was seeded with yeast c arrying DNA- BD-Dys-1 and various AD-Dyb-1 p lasmids or empty pACT2 (as a negative ... explain the physiopathology of the disease, and may also provide therapeutic clues. Dystrobrevins form a family of proteins that are uniqu e in that they are both dystrop...
Ngày tải lên: 08/03/2014, 23:20
Báo cáo y học: "Mannose-binding lectin deficiency is associated with early onset of polyarticular juvenile rheumatoid arthritis: a cohort study" pdf
... the X /Y allele was also determined by studying six 'extended' genotype groups: YA/YA, YA/XA, XA/XA, YA/O, XA/O and O/O. Statistical analysis Data are presented as median and IQR because ... are seen in individuals with the genotypes XA/XA and YA/O, whereas very low or undetectable serum MBL levels are seen in individuals with genotypes XA/O and O/O. Individuals wi...
Ngày tải lên: 09/08/2014, 10:23
Báo cáo y học: "Chromothripsis is a common mechanism driving genomic rearrangements in primary and metastatic colorectal cancer" pdf
... bioinformatic analysis of array data. OP performed the breakpoint sequencing and analyzed the data. MT generated mate-pair libraries. IR performed SOLiD sequencing and generated fragment libraries. ... calling was done using a custom analysis pipeline that identifies mutations with a non- reference allele frequency larger than 15% and a coverage of at least 10x. Sequencing da...
Ngày tải lên: 09/08/2014, 23:20
Báo cáo y học: "Kbus/Idr, a mutant mouse strain with skeletal abnormalities and hypophosphatemia: Identification as an allele of ‘Hyp’" pdf
... Otolaryn 1997, 117:20-24. 2. Yonezawa S, Yoshizaki N, Kageyama T, Takahashi T, Sano M, Tokita Y, Masaki1 S, Inaguma Y, Hanai A, Sakurai N, Yoshiki A, Kusakabe M, Moriyama A, Nakayama A: Fates ... familial X-linked hypophosphatemic rickets. Eur J Pediatr 2004, 163:622-623. 46. Yamazaki Y, Okazaki R, Shibata M, Hasegawa Y, Satoh K, Tajima T, Takeuchi Y, Fujita T, Nakahara K, Yamashita...
Ngày tải lên: 10/08/2014, 10:20
Báo cáo khoa học: "Case of a sigmoid colon cancer with metachronous metastases to the mesorectum and the abdominal wall" pdf
... sporadic reports also to the spleen, stomach, thyroid gland, abdominal wall and upper urinary tract. This is a rare case of metachronous metastases invading the mesorectum and the abdominal wall. Case presentation: ... Zizi-Sermpetzoglou, Athanasios Marinis, Andrea s Hadjimarcou, Nikolaos Paschalidis, Spyros Rizos Abstract Backround: Sigmoid colon cancer metachronous metastases commonly...
Ngày tải lên: 09/08/2014, 03:21
Báo cáo y học: "Peroxisome proliferator-activated receptor γ1 expression is diminished in human osteoarthritic cartilage and is downregulated by interleukin-1β in articular chondrocytes" doc
... used: PPARγ1 sense, 5'-AAA- GAAGCCAACACTAAACC-3'; PPARγ2 sense, 5'-GCGAT- TCCTTCACTGATAC-3'; common PPARγ1 and PPARγ2 antisense, 5'-CTTCCATTACGGAGAGATCC-3'; glyceralde- hyde-3-phosphate ... tempting to speculate that diminished expression of PPARγ in OA cartilage may, at least in part, be involved in increased expression of inflammatory and catabolic ge...
Ngày tải lên: 09/08/2014, 10:20
Báo cáo y học: "The epidemiology of medical emergency contacts outside hospitals in Norway - a prospective population based study"
... Grønlien, and Jan Nystuen from the area of Innlandet, Unni Eskeland and Olav Østebø from the area of Stavanger, and Leif Landa, Kari Hauge Nilsen, and Trond Kibsgaard in the area of Haugesund. We want ... Acute vital (life threatening) danger NACA 6 Acute cardiac or respiratory arrest NACA 7 Death Zakariassen et al. Scandinavian Journal of Trauma, Resuscitation and Emergency Medic...
Ngày tải lên: 25/10/2012, 09:56