Báo cáo y học: "γ The role of the complement and the FcγR system in the pathogenesis of arthritis" pdf
Báo cáo y học: "Cigarette Smoke Exposure Alters mSin3a and Mi-2α/β Expression; implications in the control of pro-inflammatory gene transcription and glucocorticoid function" ppt
... may lead to the alteration of both the formation and targeting of these complexes. Consequently, an oxidant-mediated reduction in the protein expression of Mi-2α and mSin3a and increased protein ... and ran the in vivo model. KFC participated in the study design and preparation of the manuscript. IMA and PAK conceived of the study, participated in i...
Ngày tải lên: 11/08/2014, 03:20
Báo cáo y học: "Cigarette Smoke Exposure Alters mSin3a and Mi-2α/β Expression; implications in the control of pro-inflammatory gene transcription and glucocorticoid function" pdf
... our understanding of the roles of these co-repressor com- plexes and thereafter their roles in disease. In summary cigarette smoke exposure reduced HDAC- 2 activity and the expression of mSin3a and ... may lead to the alteration of both the formation and targeting of these complexes. Consequently, an oxidant-mediated reduction in the protein expression of M...
Ngày tải lên: 11/08/2014, 06:22
Báo cáo y học: "Cost-effectiveness model comparing olanzapine and other oral atypical antipsychotics in the treatment of schizophrenia in the United States" ppt
... With the exception of the generic cost of risperidone, the range of possible input values was created by setting the minima and maxima of the range to be 50% and +50% of the base case value. The ... is not included in the sensitivity analyses. One-Way Sensitivity Analyses The sequential bifurcation tests indicate that the key eco- nomic outcomes of the...
Ngày tải lên: 13/08/2014, 11:22
Báo cáo y học: "Functional proteomics can define prognosis and predict pathologic complete response in patients with breast cancer" pdf
... of proteins including cyclins B1 and E1 as well as components of the protein synthesis machinery including phosphory- lated S6 ribosomal protein and 4EBP1, a group with overexpression of stromal ... from the training set. 3A. Probability of recurrence as a continuous function of the score. The rug plot shows the prognosis score for individual patients in the study....
Ngày tải lên: 13/08/2014, 13:20
Báo cáo y học: " Young adult obese subjects with and without insulin resistance: what is the role of chronic inflammation and how to weigh it non-invasively" docx
... frequent in obese patients with insulin resistance. These findings show that in young adults the only abdominal adiposity without insulin resistance, plays a scarce role in determining hepatic ... jj) the correlation between the entity of VAT and SAAT deposition and the severity of HS, all of them studied by US in basal condition, jjj) to find among the inflammat...
Ngày tải lên: 11/08/2014, 08:22
Báo cáo Y học: Nuclear proteins that bind to metal response element a (MREa) in the Wilson disease gene promoter are Ku autoantigens and the Ku-80 subunit is necessary for basal transcription of the WD gene ppt
... IR. Results of each values were expressed as the following ratio: intensity of WD cDNA/intensity of competitor and then divided by intensity of amplified actin cDNA. PC, the result of competitive ... (underlined bases denote the functional core of the MREs and the Sp1 binding element, and the mutated bases are indicated by italic type). Western blot analysis The...
Ngày tải lên: 17/03/2014, 23:20
Báo cáo y học: " TGF β-induced cartilage repair is maintained but fibrosis is blocked in the presence of Smad7" pps
... damage by injection of interleukin-1 (IL-1) into murine knee joints. After 2 days, we injected an adenovirus encoding TGFβ. On day 4, we measured proteoglycan (PG) synthesis and content. To examine ... overexpression of TGFβ stimulated repair of IL-1- and OA-damaged cartilage. TGFβ- induced synovial fibrosis was blocked by locally inhibiting TGFβ signaling in the synovial lining...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo y học: " Part I, Patient perspective: activating patients to engage their providers in the use of evidencebased medicine: a qualitative evaluation of the VA Project to Implement Diuretics (VAPID)" ppsx
... following instruction appears to be ingrained in their reasoning for bringing in the letter. These indivi- dualsstatedtheyweresimplydoingwhattheletter requested of them. ‘For one thing I was told and ... participating in the study and for bring ing in the letter for discussion. For sev eral patients it was their way of ‘paying back’ the military and other veterans, w...
Ngày tải lên: 11/08/2014, 05:21
Báo cáo y học: "B-lymphocyte stimulator/a proliferation-inducing ligand heterotrimers are elevated in the sera of patients with autoimmune disease and are neutralized by atacicept and B-cell maturation antigen-immunoglobulin" pdf
... similar binding proper- ties and in vitro activities to the BLyS and APRIL homo- trimers, and may be present in sera in similar amounts to APRIL and BLyS, we postulate that they may likely play similar ... of assay buffer. Wells were then resuspended in 100 μl of assay buffer and analyzed by using a Luminex 100 mac hine (Luminex Corporation, Austin, TX, USA). The tot...
Ngày tải lên: 12/08/2014, 12:20
Báo cáo y học: "Pro/con clinical debate: Is high-frequency oscillatory ventilation useful in the management of adult patients with respiratory failure" ppt
... What is the safety and efficacy of the device? As outlined in the following debate, there are several compelling arguments for and against the use of HFOV at this point in adults. Keywords acute ... oscillatory ventilation (HFOV) has become an increasingly common therapy. This may not have been the case if researchers had not persisted in investigating the therapy af...
Ngày tải lên: 12/08/2014, 18:21