Báo cáo y học: "Reliability of computerized image analysis for the evaluation of serial synovial biopsies in randomized controlled trials in rheumatoid arthritis" pps
Báo cáo y học: "Reliability of computerized image analysis for the evaluation of serial synovial biopsies in randomized controlled trials in rheumatoid arthritis" pps
... study determined the intraraterand inter-rater reliability of digital image analysis (DIA) of synovial biopsies from RA patients participating in clinical trials. Arthroscopic synovial biopsies ... reliability holdstrue for determination of changes in secreted proteins, such ascytokines and chemokines.Conclusion In conclusion, the findings of the present study show the relia-bility of ST analysis ... wererandomly analyzed by computer-assisted image analysis (Fig.1). For all markers, 18 high-power fields were analyzed. The images of the high-power fields were analyzed using the Qwin analysis system...
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Tài liệu Báo cáo Y học: Interallelic recombination is probably responsible for the occurrence of a new as1-casein variant found in the goat species potx
... otypic analysis (at the p rotein level), the f ewanimals yielding in their milk the as1-CasM variant wereexclusively heterozygous M/F a t the as1-Cas locus. There-fore, analysis o f their ... 3 in the 9thexon of the A alle le, which is deleted in the F allele, ismutatedtoTintheMallele, giving rise to a Ser fi Leusubstitution. Analysis of the intronic flanking sequences The flanking ... the intensity of the isoelectrofocusing bands and the surface of the relevant peak in RP-HPLC.Fig. 6. Nucleotide sequence of the expected as1-CasM cDNA obtained by genomic e xon sequencing analysis: ...
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Báo cáo y học: "Pro-apoptotic Bid is required for the resolution of the effector phase of inflammatory arthritis" pdf
... phase of inflammatory arthritis [27,28]. Since the pro-apoptotic pro-tein Bid links the extrinsic to the intrinsic pathway, we exam-ined the affect of inducing experimental inflammatory arthritis in ... & Therapy Vol 9 No 3 Scatizzi et al.Page 4 of 10(page number not for citation purposes)invasion of leukocytes, proliferation of synoviocytes resulting in the thickening of the synovial lining, ... progression of RA because they arecapable of inducing other pro-inflammatory cytokines and acti-vating matrix metalloproteinases in autocrine and paracrinefashions [56]. Inhibitors of IL-1β and...
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Báo cáo y học: "Adherence with urate-lowering therapies for the treatment of gout" pps
... was involved in the analysis of data from this study and interpretation and presentation of results. RY was involved in the interpretation of the data, anddrafting of this article. IO was involved ... was involved in the design of this project, data acquisition and analysis, interpretation of the data, and critiquing of drafts of this article. BB wasinvolved in the design of this project, analysis ... to ULD initiation, we looked separately at dis-pensings of NSAIDs, colchicine and glucocorticoids in the 30days prior to and including the date of the first ULD dispens-ing.Analyses The characteristics...
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Báo cáo y học: " Peripheral blood and neuropsychological markers for the onset of action of antidepressant drugs in patients with Major Depressive Disorder" pps
... role in the currently ongoing collection of data.Author details1Department of Psychiatry and Psychotherapy, University Medical Centre,Mainz, Germany.2Interdisciplinary Centre for Clinical Trials ... UniversityMedical Centre, Mainz, Germany.3Clinic for Psychiatry and Psychotherapy,Katzenelnbogen, Germany.4Clinic for Psychiatry and Psychotherapy, Dr.Horst-Schmidt-Kliniken, Wiesbaden, Germany.Authors’ ... immuno-inflammatory system with the aetiology and the pathophysiology of MDD.Recently, a larger panel of pro- a nd anti-inflammatorycytokines was measured in a case/control population of MDD showing...
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Báo cáo y học: "Are serum cytokines early predictors for the outcome of burn patients with inhalation injuries who do not survive" pot
... hospitalmanagement. Because of the relevance of inflammatory medi-ators as biomarkers in acute lung injury, we hypothesized that the levels of various cytokines were elevated early during the course of hospitalization ... the beads were incubated with streptavidin-phycoerythrin for 10minutes, washed, and placed in the array reader for determina-tion of the respective cytokine concentration.Statistical analysis Unpaired ... within 24 hours of admission and 5 to 7days later. Cytokine levels were profiled using multiplex antibodycoated beads. Inhalation injury was diagnosed by bronchoscopyduring the initial surgery....
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Báo cáo y học: " How to select a chiropractor for the management of athletic condition" potx
... it is likely that the sports specific his-tory and examination should include analysis of trainingand competition needs, including specific biomechanical analysis/ investigation of function ... MW: Overview of Survey Response. In: Job Analysis of Chiropractic: A Project Report, Survey Analysis and Summary of the Practice of Chiropractic within the United States. Greeley, Colorado. National ... original contributions to the content of the final manuscript. All of the authors par-ticipated in the editing and revisions of the multiple draftsthat existed between the initial and final...
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Báo cáo y học: "Mechanical complications and reconstruction strategies at the site of hip spacer implantation"
... osteosynthesis [4]. The major advantages of a hip spacer implantation are: (i) immediate treatment of the infection source by locally reaching high antibiotic levels, (ii) maintance of joint ... Generally, the surgical treatment of these fractures should be planned taking into consideration any further surgical revisions or the later prosthesis reimplantation. If possible, the insertion of ... and evaluate the effect of a metallic endo-skeleton on the pharmacokinetic properties of the interim prosthesis. Conflict of Interest The authors have declared that no conflict of in- terest...
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Tài liệu Báo cáo Y học: Interallelic complementation provides genetic evidence for the multimeric organization of the Phycomyces blakesleeanus phytoene dehydrogenase doc
... 2002understanding of the function and organization of the enzyme complex, the analysis of mutant a lleles of the ge nesinvolved in the biosynthetic pathway c an certainly providevaluable information. In ... addition of Tween 40 [39], i t can be concluded that the 482 Gly residue is important for the activity of the enzyme, likely being one of the residues m ediating substratebinding. In strain C5, ... been described for bothZygomycetes. In Phycomyces they complement neither the carR nor the carA mutants, and i n Mucor they complementneither the carP nor the carR mutants. They are white, l...
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Báo cáo y học: "What do biomarkers tell us about the pathogenesis of ankylosing spondylitis" ppsx
... MRIexamination even shows that while inflammatory changes in the spine predict the development of new syndesmophytes,complete resolution of inflammation at a vertebral cornerfollowing the institution ... pathogenesis of ankylosing spondylitis?Walter P MaksymowychDepartment of Medicine, University of Alberta, Edmonton, Alberta T6G 2S2 CanadaCorresponding author: Walter P Maksymowych, walter.maksymowych@ualberta.caSee ... investigation in AS because of the generally slow rate of progression of radiographic change [2]. Such a biomarker could then beused to enrich for rapid progressors in trials of diseasemodifying therapies....
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