... information greatlyfacilitated the discovery of novel disease-related genes and the mapping of signature genes for early diagnosis. Morespecifically, polynucleotide or oligonucleotide arrays havebeen ... 2000,233:131-140.4. Watanabe N, Ando K, Yoshida S, Inuzuka S, Kobayashi M, MatsuiN, Okamoto T: Gene expression profile analysis of rheumatoid synovial fibroblast cultures revealing the overexpression of genes ... CL: Discovery of distinctive gene expression profiles in rheumatoid synovium using cDNAmicroarray technology: evidence for the existence of multiplepathways of tissue destruction and repair....