Báo cáo y học: "Osteoporosis in experimental postmenopausal polyarthritis: the relative contributions of estrogen deficiency and inflammation" potx

... scoring 1 to 3 in each paw (maximum of 12 points per mouse) as follows: 1, swelling or erythema in one joint; 2, swelling or erythema in two joints; 3, severe swelling of the entire paw or ankylosis. Tissue ... demonstrated. Phenotypes of bone marrow lymphocytes are influenced both by OVX and by arthritis Flow cytometry analysis was performed to evaluate the effects of OV...

Ngày tải lên: 09/08/2014, 06:23

... accompanying images. A copy of the written consent is available for review by the Editor -in- Chief of this journal. Competing interests The authors declare that they have no competing interests. Authors' ... Collaboration Group. University of Zaragoza (Spain). PGR-1 Hot-Dog: a new rat model for the study of the experimentally-induced endometriosis in rats. Proceeding...

Ngày tải lên: 11/08/2014, 17:21

... vicinity of the injected cells was also observed 1 week following injection, and the intensity of the matrix staining increased with time in culture (Figures 4 and 5b). Weak staining for type ... within a small number of cells in monolayer culture. Following injection into NP tissue explants, MSCs stained strongly positive for type II collagen and matrix staining in t...

Ngày tải lên: 09/08/2014, 01:22

Ngày tải lên: 09/08/2014, 08:22

... pathway rather than the MEK/ MAPK pathway. Cyclin B 1 and cyclin D 1 Consistent with the increased chondrocyte growth, the expression of the cell proliferation markers cyclin D 1 and cyclin B 1 ... this staining between these two groups (Figure 3a to 3d). Type-IX collagen antibody staining of the culture specimens showed the intensity of this staining in the chondroc...

Ngày tải lên: 09/08/2014, 10:23

... of intracellular signaling of the Jak–STAT pathway used by several cyto- kines. They act by inhibiting the kinase activity, by competing with substrates needed for signal transduction, and by targeting ... exclusively by stromal cells in the thymus and lymph nodes, by lymph vessels in the intestine and by the epidermis [32]. In CCX-CKR –/– mice, trafficking of dend...

Ngày tải lên: 09/08/2014, 14:22

... chains of Phe9, Tyr10 and Phe21 facing the Pro18 ring and the hydrophobic side chains of Val17 and Ile7, respectively. Therefore, the peptide region that contains both the 8–10/17–19 b-sheet and the ... thermolysin-linearized form. In the cyclic MccJ25, the stability is likely to be reinforced by the constraining strength of the circular backbone. Interesting...

Ngày tải lên: 23/03/2014, 21:20

... contributed to the clinical and rating evaluations dur- ing the follow-up periods. KH conceived of the study and participated in its study and coordination. Both authors read and approved the final manuscript. References 1. ... antipsychotic drugs altogether because of the risk of extrapyramidal side effects (EPS) in patients with psychotic depression treated with...

Ngày tải lên: 08/08/2014, 23:21

... hairpin sequences conserved in C. savignyi so that both miR and miR* products are conserved. Interestingly, only 11 of these correspond to the 41 known C. intestinalis family members. The remaining ... strat- egy: the application of the known mechanisms of miR biogenesis and the elimination of false positives by exam- ining small RNA sequencing reads from the antisen...

Ngày tải lên: 09/08/2014, 20:21

... domain and the C domain are the least conserved domains of MIKC-type proteins [5]. Besides structural diff erences in the K domain, the length of the sequence and the number of exons encoding the ... gametophyte (pollen) development is dominated by the activity of MIKC*-group genes (blue) and the development of the female gametophyte (embryo sac), embry...

Ngày tải lên: 09/08/2014, 20:22