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Báo cáo y học: "The differential contribution of tumour necrosis factor to thermal and mechanical hyperalgesia during chronic inflammation" pps

Báo cáo y học:

Báo cáo y học: "The differential contribution of tumour necrosis factor to thermal and mechanical hyperalgesia during chronic inflammation" pps

... Nociceptive and inflammatory effects of subcutaneous TNFalpha. Pain 2000, 85:145-151.Figure 6Actions of tumour necrosis factor (TNF) on hyperalgesia in health and in chronic inflammationActions of tumour ... http://arthritis-research.com/content/7/4/R807R807Vol 7 No 4Research articleThe differential contribution of tumour necrosis factor to thermal and mechanical hyperalgesia during chronic inflammationJulia J Inglis1, Ahuva ... Allchorne A, Safieh-Garabedian B, Poole S: Cytokines,nerve growth factor and inflammatory hyperalgesia: the contri-bution of tumour necrosis factor alpha. Br J Pharmacol 1997,121:417-424.4....
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Báo cáo y học: "The differential expressions of 78-kDa glucose-regulated protein of infiltrating plasma cells in peripheral joints with the histopathological variants of rheumatoid synovitis" pptx

... in RA synovium relative to those in OAsynovium (P < 0.001) and in synovium with follicular synovitisrelative to that with diffuse synovitis (P < 0.001). Analyses byflow cytometry and immunoblotting ... production of pathogenic autoantibodies.Methods The variants of rheumatoid synovium werehistopathologically classified into follicular and diffuse synovitis.Immunohistochemical and double-immunofluorescent ... production of patho-genic autoantibody such as anti-CCP.Materials and methodsPatients and samplesSynovium and synovial fluid were taken at total knee arthro-plasty or arthroscopic synovectomy for...
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Báo cáo khoa học: The relative contribution of mannose salvage pathways to glycosylation in PMI-deficient mouse embryonic fibroblast cells pdf

Báo cáo khoa học: The relative contribution of mannose salvage pathways to glycosylation in PMI-deficient mouse embryonic fibroblast cells pdf

... disorders of glycosylation (CDGs)are metabolic syndromes with a wide symptomatology and severity, stemming from deficient N-glycosylation of proteins [11]. CDG type I defects are due to insuffi-cient ... pathways to glycosylation may be substantial[13–16], mannose salvage pathways have received rela-tively little attention and have yet to be systematicallyinvestigated [17]. Sources of salvaged ... se-quon seemed to reflect the glycosylation capability of the cells.Glycosylation efficiency of mutant DNase Iexpressed in CDG-Ib fibroblast cellsWe measured the glycosylation efficiency of DNase Iin...
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Báo cáo y học: "The evolving story of medical emergency teams in quality improvement"

... development of METs rose from observations that, in the majority of patients, premonitory signs and symptoms of cardio-pulmonary instability are often present hours before clinicaldeterioration [6]. By ... Sunnybrook Health Sciences Centre, University of Toronto, 2075 Bayview Avenue, Room D108, Toronto, ON M4N 3M5, Canada2Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto ... patient and a weekly 1-hourCommentaryThe evolving story of medical emergency teams in qualityimprovementAndré Carlos Kajdacsy-Balla Amaral1 and Kaveh G Shojania21Department of Critical...
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Báo cáo y học: "The Versatile Use of Temporoparietal Fascial Flap"

... University, Faculty of Medicine, Izmir, TURKEY. 2. Clinic of Plastic Reconstructive and Aesthetic Surgery, Public Hospital, Mus, Turkey. 3. Clinic of Plastic Reconstructive and Aesthetic Surgery, ... aim of this study is to report our experience in versatile use of temporo-parietal fascial flap (TPFF) and discuss the surgical anatomy and technique. Patients and Methods: A total number of ... injury may be seen. Patient reports Patient 1 A 71-year old male with a history of penetrating trauma, admitted to Ophthalmology clinic for slowly growing mass on his left eye (Figure 2 and...
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Báo cáo y học: "The Natural History of Hepatitis C Virus (HCV) Infection"

... the cytoplasm of hepatocytes, but is not directly cytopathic. Persistent infection appears to rely on rapid production of virus and continuous cell -to- cell spread, along with a lack of vigorous ... by 6 months, and chronic hepatitis develops. The rate of chronic HCV infection is affected by many factors, including the age at time of infection, gender, ethnicity, and the development of ... Division of Gastroenterology and Hepatology, University of California-Irvine, Irvine, California USA. His clinical interests include natural history and management of hepatitis B and C. Timothy...
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Báo cáo y học: "The primary prevention of birth defects: Multivitamins or folic acid"

... pregnancy complications, and maternal diseases during pregnancy according to gestational month, and any family history of CAs. In order to standardize the answers, mothers were asked to read ... bbiiooggrraapphh y y Andrew E. Czeizel, MD, PhD is the scientific director of Foundation for the Community Control of Hereditary Diseases, Budapest, and professor of Faculty of Genetics, Eötvös ... Registry (HCAR) [18] which is a national-based registry of cases with CAs. Notification of CAs is mandatory for physicians, and most are reported by obstetricians (in Hungary practically all...
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Báo cáo Y học: The inhibitory region of troponin-I alters the ability of F-actin to interact with different segments of myosin pot

Báo cáo Y học: The inhibitory region of troponin-I alters the ability of F-actin to interact with different segments of myosin pot

... ability of tropo-myosin to extend the inhibitory activity of the troponin Imolecule from one to seven actin monomers.Correspondence to S. V. Perry, Department of Physiology, School of Medicine, ... Fattoum4, S. Victor Perry1 and Barry A. Levine1,21Department of Physiology, School of Medicine and 2School of Biosciences, University of Birmingham, Birmingham, UK;3School of Biological ... actomyosinATPase in situ by a steric mechanism [12–14] and it hasbeen suggested that the role of TnI is to induce thebinding of tropomyosin to actin [3]. Nevertheless theability of TnI to...
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Báo cáo Y học: The solution structure of gomesin, an antimicrobial cysteine-rich peptide from the spider pptx

Báo cáo Y học: The solution structure of gomesin, an antimicrobial cysteine-rich peptide from the spider pptx

... Ha-Ha peaks to be obtainednear the r esidual water diagonal, especially between Cys2 and C ys15, Cys6 and Cys11, Arg 4 and Thr13. The splitting of the resonance of backbone NH and Ha protons allowscomplete ... (Arg5, Lys8, and Lys19) distributed oneach side of the s heet reduces considerably the hydropho-bicity of the surface of androctonin when compared to thetwo other peptides (Fig. 5 ).Mode of actionThe ... theother face of gomesin. The central portion of PG-1 isparticularly hydrophobic as it contains only a polar residuesLeu5, Cys6, Tyr7, Cys8, Phe12, Cys13, Val14, Cys15 and Val16 alternatively distributed...
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Báo cáo Y học: The phosphotransferase system of Streptomyces coelicolor IIACrr exhibits properties that resemble transport and inducer exclusion function of enzyme IIAGlucose of Escherichia coli pptx

Báo cáo Y học: The phosphotransferase system of Streptomyces coelicolor IIACrr exhibits properties that resemble transport and inducer exclusion function of enzyme IIAGlucose of Escherichia coli pptx

... radiolumi-nography on a phosphoimager (Fuji).Enzyme assaysIIACrractivity was assayed by complementation of theglucose-specific PTS of E. coli measuring phosphoenolpyru-vate-dependent phosphorylation of ... significantsimilarity to enzyme IIAGlc of E. coli, a global-acting factor of carbon metabolism. We provided evidence that the geneis expressed in vivo and that IIACrris phosphorylated in vitroby the general ... 75 and the experimentally provenphosphorylation site histidine 90 of E. coli IIAGlc[27,28].Overexpression and purification of S. coelicolorIIACrr and IIACrr(H72A) To study the function of...
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