Báo cáo y học: "Early rheumatoid arthritis is characterized by a distinct and transient synovial fluid cytokine profile of T cell and stromal cell origin" pptx
Báo cáo y học: "Early rheumatoid arthritis is characterized by a distinct and transient synovial fluid cytokine profile of T cell and stromal cell origin" pptx
... from that of other early inflammatory arthritides and of established RA. The nature of the cytokines present in the synovial fluid of patients with early RA suggests that this response is likely to influence ... early inflammatory arthritis who subsequently developed RA had a distinct but transient synovial fluid cytokine profile. The levels of a range of...
Ngày tải lên: 09/08/2014, 06:22
Báo cáo y học: "Collagen-induced arthritis is exacerbated in IL-10-deficient mice" pps
... play a dual role in disease activity. Anti-IFN-γ treatment early in the course of disease suppresses arthritis, whereas neutralization of IFN-γ late in disease exacerbates arthritis. In addition, IFN-γ ... to rheumatoid arthritis. Keywords: antibody, arthritis, autoimmunity, cytokines Open Access Although CIA is considered a Th1-type disease mediated by IFN-γ, the role of...
Ngày tải lên: 09/08/2014, 01:21
Báo cáo y học: "Fibroblast activation protein is expressed by rheumatoid myofibroblast-like synoviocytes" ppt
... was gen- erated with 5'-GTTATTGCCTATTCCTATTATG-3' and 5'- GTCCATCATGAAGGGTGGAAA-3'. The MMP-1 PCR prod- uct was generated with 5'-CTGAAGGTGATGAAGCAGCC- 3' and 5'-AGTCCAAGAGAATGGCCGAG-3'. ... 4 Immunohistochemical analysis of activation markers in synovial membranes of rheumatoid arthritisImmunohistochemical analysis of activation markers i...
Ngày tải lên: 09/08/2014, 08:23
Báo cáo y học: "Human rheumatoid arthritis tissue production of IL-17A drives matrix and cartilage degradation: synergy with tumour necrosis factor-α, Oncostatin M and response to biologic therapies" ppt
... L, Danisit TIRA Group: Connective tissue metabolism in patients with unclassified polyarthritis and early rheumatoid arthritis. Rela- tionship to disease activity, bone mineral density, and radio- graphic ... MMP-1: TIMP-1 ratio in rheumatoid arthritis synovial explant culturesIL-1 7A significantly shifts the MMP-1: TIMP-1 ratio in rheumatoid arthritis synovial explant cul...
Ngày tải lên: 09/08/2014, 14:22
Báo cáo y học: "Early innate immune events induced by prolonged cold ischemia exacerbate allograft vasculopathy" potx
... R, Kucheryavaya AY, Rahmel AO, Hertz MI: Registry of the International Society for Heart and Lung Transplantation: Twenty-sixth official adult heart transplant report-2009. J Heart Lung Transplant 2009, ... DD, Argenziano M, Stewart AS, Oz MC, Naka Y: The effect of ischemic time on survival after heart transplantation varies by donor age: An analysis of the United Devitt et al. Jou...
Ngày tải lên: 10/08/2014, 09:23
Báo cáo y học: "Early onset pauciarticular arthritis is the major risk factor for naproxen-induced pseudoporphyria in juvenile idiopathic arthritis" pdf
... informa- tion was obtained by review of follow-up visits and by stand- ardized telephone interviews. Statistical analysis was done by χ 2 test and linear multiple discriminant analysis for categorial data ... naproxen dosage and use of comedications are mostly a consequence of increased disease activity. As indicated in the present study JIA disease activity, as indicated...
Ngày tải lên: 09/08/2014, 10:20
Báo cáo y học: "Early and long-standing rheumatoid arthritis: distinct molecular signatures identified by gene-expression profiling in synovia" pot
... full access to all of the study data and takes responsi- bility for the integrity of the data and the accuracy of the data analysis. He helped conceive of the study and participated in its design ... RA stage might help to choose the most appropriate treatment. Introduction Rheumatoid arthritis (RA) is a chronic, autoimmune, and inflammatory polyarthritis that induces...
Ngày tải lên: 09/08/2014, 14:22
Báo cáo y học: "Adalimumab clinical efficacy is associated with rheumatoid factor and anti-cyclic citrullinated peptide antibody titer reduction: a one-year prospective study" potx
... M, Emery P, Feldmann M, et al.: Infliximab and methotrexate in the treatment of rheumatoid arthritis. Anti-Tumor Necrosis Factor Trial in Rheumatoid Arthritis with Concomitant Therapy Study Group. ... show any manifestation potentially related to a full-blown lupus disease. Accordingly, IgG anti-dsDNA autoantibodies seemed to be at low titers and to display low affinity, as dem...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo y học: "Pro-apoptotic Bid is required for the resolution of the effector phase of inflammatory arthritis" pdf
... degra- dative phase of apoptosis through the activation of caspases 3 and 7 [23]. An additional pathway of death receptor-induced cell death may proceed through the mitochondrial pathway by activating ... numbers are associated with articular destruction in RA patients [2,3] and these macrophages are highly activated and contribute directly to synovial inflammation and des...
Ngày tải lên: 09/08/2014, 10:20
Báo cáo y học: "Collagen-induced arthritis in C57BL/6 mice is associated with a robust and sustained T-cell response to type II collagen" pot
... activation of Toll-like receptors. The therapeutic profile of CIA in the B6 mouse was similar to that of RA, with a therapeutic action of methotrexate at a dose comparable to human therapy. This ... vehicle alone. Each experiment was performed twice. Statistical analysis Statistical analysis was performed by one-way analysis of var- iance followed by Dunnett multiple compa...
Ngày tải lên: 09/08/2014, 10:21