Báo cáo y học: "Intra-articular injections of high-molecular-weight hyaluronic acid have biphasic effects on joint inflammation and destruction in rat antigen-induced arthritis" ppt

... 3 Research article Intra-articular injections of high-molecular-weight hyaluronic acid have biphasic effects on joint inflammation and destruction in rat antigen-induced arthritis Andreas Roth 1 , ... total score of 8 for acute inflammation. Chronic joint inflammation – based on the parameters hyper- plasia of synovial lining cells, infiltration by...

Ngày tải lên: 09/08/2014, 06:22

... the effects of the intervention, beyond any seasonal effects. It is encourag- ing that findings indicate improvements in a number of self-reported measures including aspects relating to con- centration, ... during the daytime affects circadian rhythms of urinary melatonin and salivary immunoglobulin A. Chronobiol Int 1999, 16:359-371. 28. Wakamura T, Tokura H: Influence of brig...

Ngày tải lên: 10/08/2014, 09:20

... solution of FITC was added to the final concentration of 0.05 mgÆmL )1 and the incubation was continued for 40 min at 28 °C. The reaction was quenched by addition of 2 M NH 4 Cl (final concentra- tion ... channeling; eukaryotic protein synthesis; BIAcore analysis. Aminoacyl-tRNA synthetase (ARS) and eEF1A are the proteins that advance the translation elongation cycle. ARS binds ATP, a...

Ngày tải lên: 21/02/2014, 15:20

... effective in inhibiting the activity of purified recombin- ant MTE-I in an in vitro assay performed in a Hepes-based buffer containing only KCl. Information about the tertiary structure and of ion requirements ... I., Finkielstein, C.F. & Podesta ´ , E.J. (1997) Involvement of arachidonic acid and the lipoxygenase pathway in mediating luteinizing hormone-induced testo...

Ngày tải lên: 08/03/2014, 09:20

... wash and eluate fractions were analyzed by Western blotting. First we examined the binding of MCMs to the H3/H4 resin using an antibody against the conserved ATP binding domain of all MCM proteins ... Preliminary experiments also indicate consistent inhibition of the expression of a plasmid-borne reporter gene upon overexpression of MCM2 with muta- tions in the holoenzyme intera...

Ngày tải lên: 17/03/2014, 10:20

... bound weakly (1–2% of input) to the N- and C-terminal regions of CBP, and binding to the correspond- ing regions of p300 was even weaker ( 0.5–1% of input). By contrast, binding of either IRF-3E5 ... C-terminal end-point of this interaction domain is located between amino acids 370 and 388. By contrast, binding to the N2 region of CBP could be achieved with only the first...

Ngày tải lên: 17/03/2014, 10:20

... enzymes points to conservation of three separate domains. Domain 1 contains Lys353 and Arg360; domain 2, Ser402, Gly403, His404, and domain 3, Arg490 and His496. This shows clearly that the binding ... Software. Assay of PhoN-Se brominating activity. The brominating activity of PhoN-Se was measured by the phenol red assay as mentioned above but using sodium acetate (pH 4.6) instea...

Ngày tải lên: 24/03/2014, 03:21

... reactants, might in fact be due to the consumption of CRP by ICs [35]. With this in mind we find the high fre- quency (4 of 4) of anti-CRP in patients with ongoing kidney involvement interesting, given ... of immune complexes to erythrocyte CR1 (CD35): difference in requirement of classical pathway components and indication of alternative pathway-mediated binding in C2...

Ngày tải lên: 09/08/2014, 01:23

... marked suppression of joint destruction and osteoclast activity by intra-articular injection of RNODN. These results suggest the inhibitory effect of RNODN on the induction and activity of osteoclasts. ... intra-articular injection of RNODN on joint destruction and osteoclast activity in rats with CIA To evaluate the effect of RNODN on joint destruction...

Ngày tải lên: 09/08/2014, 08:22

... interdisciplinary collaboration. As pointed out by the director of the institute, Marc Feldmann, following the rapidly growing activity in the past few years in defining stem cell participation in autoimmune ... inhibitory effects of MSCs on T-cell proliferation, there were only relatively minor and reversible effects on the T-cell effector function, as measured by IFN-γ p...

Ngày tải lên: 09/08/2014, 08:23