Báo cáo y học: "Natural killer T cells and rheumatoid arthritis: friend or foe" ppt
Báo cáo y học: "Natural killer T cells and rheumatoid arthritis: friend or foe" ppt
... communication network that results in
TGF-β1 secretion is only partially understood. Kim et al.,
propose that Vαi NKT cells suppress the production of
TGF-β1 by synovial cells through the production ... the precise mechanism(s) by
which Vαi NKT cells are attracted to synovial tissue and
the reason(s) why they get activated locally in the K/BXN
serum transfer model to induce TGF-β1 hav...
Báo cáo y học: "Androgen conversion in osteoarthritis and rheumatoid arthritis synoviocytes – androstenedione and testosterone inhibit estrogen formation and favor production of more potent 5α-reduced androgens" ppt
... as to how
ASD and testosterone are able to inhibit these two important
proinflammatory enzyme pathways in synovial cells of RA and
OA patients.
Competing interests
The author(s) declare that they ... gender and therapy. These stimulated, cen-
tral enzyme pathways can be inhibited by administration of the
two androgens ASD and testosterone. This study provides a
further rationale to...
Báo cáo y học: "The relationship between cancer and rheumatoid arthritis: still a large research agenda" ppsx
... long-term tobacco histories. Third, as
we learn to subtype RA, it would be important to look at the
relationship between anti-cyclic citrullinated peptide antibody
status and malignancy. Is the ... Bongartz T, Sutton AJ, Sweeting MJ, Buchan I, Matteson EL,
Montori V: Anti-TNF antibody therapy in rheumatoid arthritis
and the risk of serious infections and malignancies: system-
atic re...
Báo cáo y học: "Natural killer cells and autoimmunity" doc
... activation receptors, allowing them to respond to
ligands on potential target cells [17–20]. The ligands for
activation receptors are often closely related to the ligands
for inhibitory receptors. ... ability to lyse tumor cells without prior
sensitization, more recent work has demonstrated that
they have a crucial role in the initial defense against
pathogens and are particularly impor...
Báo cáo y học: "CD25brightCD4+ regulatory T cells are enriched in inflamed joints of patients with chronic rheumatic disease" potx
... production,
indicating a potential role for regulatory T cells to influence
the inflammatory processes in the joint. These features
were apparent in the vast majority of the patients despite
the different treatments ... patients with JIA it
has been reported that T cells in synovial fluid are not in
active cell cycle [28].
This study is the first to demonstrate that CD25
bright
CD4
+...
Báo cáo y học: "Natural killer cell dysfunction is a distinguishing feature of systemic onset juvenile rheumatoid arthritis and macrophage activation syndrome" pot
... cytolytic activity in patients with juvenile rheumatoid arthritis (JRA)NK cell cytolytic activity in patients with juvenile rheumatoid arthritis
(JRA). Activity of NK cells was determined after ... NK cytolytic activity and perforin/
granzyme B expression between the patient and control
groups. The rank correlation test was used to characterize
the relationship between NK cell acti...
Báo cáo y học: "Recruitment of dendritic cells and macrophages during T cell-mediated synovial inflammation" doc
... These
observations provide qualitative support to the quantitative
studies on inflammatory cells obtained from SRT by enzymatic
digestion (Figure 3c). Importantly, they show that Mϕ are a
numerically small ... [12,43], there-
fore, may result from the encounter between autoreactive
effector T cells and immature DCs and these cells may exac-
erbate disease by permitting recursive c...
Báo cáo y học: "Adult mesenchymal stem cells and cell-based tissue engineering" doc
... populations with more
limited capacity for differentiation; specifically, monopo-
tent or bipotent cells may have differentiation potentials
developmentally adapted to (and perhaps restricted to)
the ... undiffer-
entiated cells. Constitutive expression of cytokines, such
as granulocyte-colony stimulating factor, stem cell factor,
leukemia inhibitory factor, macrophage-colony stimulatin...
Báo cáo y học: "dentification of blood biomarkers of rheumatoid arthritis by transcript profiling of peripheral blood mononuclear cells from the rat collagen-induced arthritis model" doc
... were
among the genes that best correlated with laboratory indices.
The gene that exhibited the strongest correlation with total
white cell, and total and percentage neutrophil counts was
Versican, ... follows: forward,
5'-CGCCTAAGACACTACGTATGCTTGT-3'; reverse, 5'-
TTGGTCCTATGTTGACTGTTTCTCA-3'; and probe, 5'-
AGCATAGTCATTCCCTCTAAGCCAAAGAAGGTTC-3',
labeled wi...
Báo cáo y học: "Class effect of pharmacotherapy in bipolar disorder: fact or misbelief" pptx
... that combination treatment does
better than monotherapy. However, patients stabilized
on combination treatment might do worse if shifted to
monotherapy, and patients refractory to monotherapy
could ... interpreted the results and wrote the
first draft, and commented on following drafts. XG contributed to the
interpretation of results, wrote subsequent drafts. EV contributed to the
liter...
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