Báo cáo y học: "The P2X7 receptor is a candidate product of murine and human lupus susceptibility loci: a hypothesis and comparison of murine allelic products" potx

... 3 Research article The P2X 7 receptor is a candidate product of murine and human lupus susceptibility loci: a hypothesis and comparison of murine allelic products James I Elliott, John H McVey and ... PS and associated proteins are major targets of autoantibodies in SLE [8], cells stimulated via the P2X 7 receptor may be a significant source of...

Ngày tải lên: 09/08/2014, 06:22

... GPVI was functional, we measured tyrosine phosphorylation of the FcR c-chain and the tyrosine kinase Syk, which is tyrosine phosphorylated and activated early after GPVI engagement. Phosphorylation ... c-chain in COS-7 and K562 cells, and that the transmembrane arginine and cytoplasmic domain of GPVI are necessary for association with the FcR c-chain. Moreover, the FcR c-chain...

Ngày tải lên: 22/02/2014, 07:20

... Janwityanujit 1 1 Division of Allergy, Immunology and Rheumatology, Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Rama 6 Road, Bangkok10400, Thailand 2 Research ... genotype and clinical manifestation or laboratory profiles of SLE also cannot be statistically demonstrated. In conclusion, we cannot verify any association between VDR gene Bs...

Ngày tải lên: 09/08/2014, 07:20

... Instrumental Analysis, Niigata University, Japan Binding of lamin B receptor (LBR) to chromatin was studie d by means o f an in vitro assay system involving recombinant fragments of human LBR and Xenopus ... Biochemistry, Faculty of Science, Niigata University, Japan; 4 Laboratory of Applied Molecular Biology, Department of Applied Biochemistry, University of Osaka Prefectur...

Ngày tải lên: 22/02/2014, 04:20

... containing NBD2 is mutated in persistent hyperinsulinaemic hypoglycaemia of infancy. The disease is autosomal recessive and is characterized by profound neonatal hypoglycaemia and inappropriate ... 28079– 28082. 34. Matsuoka, T., Matsushita, K., Katayama, Y. , Fujita, A. , Inageda, K., Tanemoto, M., Inanobe, A. , Yamashita, S., Matsuzawa, Y. & Kurachi, Y. (2000) C-termina...

Ngày tải lên: 31/03/2014, 08:20

... in Diagrammatic representation of the interplay between inflammatory mediators and cellsFigure 3 Diagrammatic representation of the interplay between inflammatory mediators and cells. Tissue damage ... the production of the pro-inflamma- tory cytokines IL-1β and IL-18, and potentially the innate immune response, was recently and beautifully described by Mariathasan and colle...

Ngày tải lên: 11/08/2014, 08:21

... positively skewed; therefore, they were transformed logarithmically to approximate normal distribution, and such data were analysed statistically. Statistical analysis of the data analysis was carried ... Mukawa H, Tomida T, Suzuki T, Kamiya H, Matsui H, Hayakawa T. Relation of a common methylenetetrahydrofolate reductase mutation and plasma homocysteine with intimal hyperplas...

Ngày tải lên: 03/11/2012, 09:49

... and is predominantly linear. Potato arabinogalactan consists of 86% D -galactose and 6.6% L -arabinose, while soy arabinogalactan consists of 57% D -galactose and 38% L -arabinose. Methylation analysis demonstrated ... duplicate. The hydrolysis activity of GALA with different arabino- galactans was measured in duplicate by HPAEC and MALDI-TOF MS after incubation of 1 mgÆmL )...

Ngày tải lên: 21/02/2014, 01:21

... n and chromato graphy was perfo rmed as describe d in Materials a nd methods. Enzyme activity was a nalysed by the standard assay and the i mmunoreactivity was detected by Western blot analysis and ... variants of TPP II ( i.e. rat, mouse, fruit y, Arabidopsis thaliana, Caenorhabdit is elegans and Schizosaccharo myces pombe), and at least three human EST-clones covering th...

Ngày tải lên: 21/02/2014, 15:20