Báo cáo y học: "Clinical response to discontinuation of anti-TNF therapy in patients with ankylosing spondylitis after 3 years of continuous treatment with infliximab" ppsx

... to 3 years [5,6]. Our study is the first to examine the clinical response to discontinuation of long-term infliximab therapy Table 1 Clinical and laboratory findings for 42 patients with ankylosing ... Bath Ankylosing Spondylitis Disease Activity Index; BASFI, Bath Ankylosing Spondylitis Function Index; BASMI, Bath Ankylosing Spondylitis Metrology Index; CR...

Ngày tải lên: 09/08/2014, 06:22

Ngày tải lên: 09/08/2014, 06:23

... (kg/m 2 ) 29. 039 6±4.0172 27.9001 3. 5504 0 .30 9 Smoking (%) 19 (% 63. 3) 11 (% 55) 0 .38 3 Hypertension (%) 19 (% 63. 3) 7 (% 35 .0) 0.082 Diabetes mellitus (%) 13 (% 43. 3) 5 (% 25.0) 0. 237 Total cholesterole ... vitamins and trace elements in study population. Patients with CAD (n =30 ) Control group (n=20) P value Retinol (mmol/I) 0 .35 21±0. 131 9 0. 431 3±0.0465 0....

Ngày tải lên: 25/10/2012, 10:51

... brain after single oral administration of fluvoxamine: a positron emission tomography study using [ 11 C]SA45 03. Biol Psychiatry 2007, 62:878-8 83. 8. Trzepacz PT, Baker RW, Greenhouse J: A symptom ... glutamate, g-aminobutyric acid, dopamine, serotonin, norepinephrine) and, ulti- mately, to the development of delirium [1]. The endoplasmic reticulum protein sigma-1 receptors play a...

Ngày tải lên: 08/08/2014, 23:21

... (19%) History of diabetes mellitus, n (%) 3 (10%) History of hyperlipidaemia, n (%) 2 (6.5%) History of myocardial infarction, n (%) 1 (3. 2%) History of angina, n (%) 2 (6.5%) History of stroke ... attack at 52 years of age, two males with a history of angina at the ages of 48 and 64 years, and one patient with myocardial infarction (MI) at age 48 years. Twenty...

Ngày tải lên: 09/08/2014, 14:20

... 12 months in 10 patients (1 to 2 years in four patients, 2 to 5 years in five patients, and 16 years in one patient). Lupus treatment at the time of serum sampling in the 15 patients with subsequent ... longer median duration of SLE in the nephritis group (6 years; range, 0.25 to 36 years) compared with the group without nephritis (2.1 years; range,...

Ngày tải lên: 09/08/2014, 14:21

... frequency of CTX-II immunoreactivity within the zones of interest two and six weeks after ovariectomyEffect of treatment on the frequency of CTX-II immunoreactivity within the zones of interest ... 48 to 73 years, mean age 59 years) were included in the study. None of the patients had symptomatic OA, and this was confirmed by WOMAC index (Western Ontario and McMaster...

Ngày tải lên: 09/08/2014, 01:22

... Clin Invest 1999, 104: 139 3-1401. 21. Yamamura M, Kawashima M, Taniai M, Yamauchi H, Tanimoto T, Kurimoto M, Morita Y, Ohmoto Y, Makino H: Interferon-gamma- inducing activity of interleukin-18 in ... The same tendency was observed for the response to Th1-inducing cytokines in RA. These results indicate that RA-PBMCs are defective in their response to Th1-inducing cytokines,...

Ngày tải lên: 09/08/2014, 01:23

... p38 mitogen-activated protein kinase (MAPK) diminish inflammatory arthritis in experimental animals. This may be effected by diminishing the production of inflammatory mediators, but this kinase ... beta. protein kinase activity, protein kinase B phosphorylation, and retinoblastoma hyperphosphorylation in IL-2-stimulated T cells independently of p38 mitogen-activated protein kinase. J...

Ngày tải lên: 09/08/2014, 01:23

... demonstrated efficacy in patients with active rheumatoid arthritis (RA) and an inade- quate response to methotrexate, and in those with an inade- quate response to anti-TNF therapy [1 -3] . Abatacept ... protein consisting of the extracellular domain of human cytotoxic T-lymphocyte-associated antigen-4 linked to the Fc (hinge, CH2 and CH3 domains) portion of huma...

Ngày tải lên: 09/08/2014, 10:20