Báo cáo y học: "Amplification of autoimmune disease by infection" potx
Báo cáo y học: "Amplification of autoimmune disease by infection" potx
... with MHV-68 in the synovium
involving all cell types including fibroblasts and synovial
lining cells [4]. By electron microscopy many of these cells
were lytically destroyed, extracellular free ... Indeed, the lymphoid organs of Waldeyer’s
ring, where EBV is thought to reactivate, are sites of
Review
Amplification of autoimmune disease by infection
David N Posnett
1,2
and Dmit...
Báo cáo Y học: Effect of the disease-causing mutations identified in human ribonuclease (RNase) H2 on the activities and stabilities of yeast RNase H2 and archaeal RNase HII pot
... works
binding affinity of the protein to the substrate is not
seriously affected, or only slightly affected, by the
mutation of Gly10 to Ala or Ser, but is greatly
decreased by that to Leu or Pro.
The ... proteins exhibited enzymatic activ-
ity. However, only the enzymatic activity of Sc-G42S* was greatly reduced
compared to that of the wild-type protein. Gly42 is conserved as Gly1...
Báo cáo y học: "Genetics of rheumatic disease" pdf
... J:
Re-evaluation of putative rheumatoid arthritis susceptibility
genes in the post-genome wide association study era and
hypothesis of a key pathway underlying susceptibility. Hum
Mol Genet 2008, ... necessary to type so-called tag SNPs, which identify
these areas of limited variability [2], to achieve good
representation of the total amount of genetic variation. Most
typed SNPs are...
Báo cáo y học: "Determinants of late disease-stage presentation at diagnosis of HIV infection in Venezuela: A case-case compariso" ppt
... Sexually Transmitted
Diseases and HIV/AIDS, National Program of HIV/AIDS, Ministry of Health and Social Development, Valencia, Venezuela,
4
Department of
Biology and Society, Faculty of Earth ... University of Amsterdam, Amsterdam, The Netherlands,
5
Department of Parasitology,
Faculty of Health Sciences, University of Carabobo, Valencia, Venezuela and
6
Centre of Info...
Báo cáo Y học: Repression of FasL expression by retinoic acid involves a novel mechanism of inhibition of transactivation function of the nuclear factors of activated T-cells pptx
... whereby it i s translocated back to the
cytoplasm [19,39]. While NFAT dephosphorylation is
mediated by calcineurin, rephosphorylation is catalyzed by
a variety of serine kinases, such as glycogen ... binding specificity of plant lectins to yeast cells by biotin-avidin
system and its application to the classification of yeast cells. Anal.
Biochem. 254, 41–48.
31. Na, S .Y. , Kang, B...
Báo cáo Y học: Characterization of heparin binding by a peptide from amyloid P component using capillary electrophoresis, surface plasmon resonance and isothermal titration calorimetry ppt
... all types of
amyloid deposits [1–5]. Because of its largely unknown
physiological function [6], its affinity for amyloid, and
possible involvement in the pathogenesis of systemic lupus
erythematosus ... the
specificity of the glycosaminoglycan interaction with regard
to peptide sequence by applying two additional biophysical
techniques and showing that the N-terminal part of the
pep...
Báo cáo y học: " Regulation of Sox9 activity by crosstalk with nuclear factor-κB and retinoic acid receptors" pptx
... were analyzed by densitometry using Kodak
Digital Science software (Eastman Kodak, Rochester, NY,
USA). Data were analyzed by paired t-tests, or by analysis of
variance followed by Tukey's multiple ... command of p300, because Sox9 activity was
reduced by approximately 50% when NF-κB was activated.
However, the demand for p300 is controlled not only by rela-
tive affinity...
Báo cáo y học: "Imaging of gout: findings and utility" potx
... to
an attack of acute gout [29]. Erosions were detected three
times more frequently by high-resolution US than on X-ray
imaging. In this study, US aided in the diagnosis of gout by
identifying sonographic ... study using US
is the first to link the gap between asymptomatic hyper-
uricemia and symptomatic deposition of urate, namely gout.
Could we call this stage asymptomatic deposit...
Báo cáo y học: " Regulation of cardiac microRNAs by serum response factor" potx
... expression of a number of microRNAs. Interestingly, downregulation
of miR-1, miR-133a and upregulation of miR-21 occurred by 7 days of age in these mice, long before the onset of
cardiac hypertrophy, ... activity, respectively (p < 0.05, n = 3).
Myocardin (MYOCD) strongly activated the mir-21 promoter activity (p < 0.05). p49 also repressed mir-21-luciferase reporter activ...
Báo cáo y học: "Inhibition of NFκB by the natural product Withaferin A in cellular models of Cystic Fibrosis inflammation" pps
... anti-
inflammatory agent in models of CF related inflammation mediated by NFκB.
Findings
Cystic Fibrosis (CF) is one of the most common lethal
autosomal recessive diseases in humans. It is caused by
mutations ... immortalized CF
airway cell line homozygous for ΔF508 mutation and the
CF 14 clinically isolated mucoid strain of PA (originally
from the laboratory of Dr. M.C. Wolfgang,...
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