Báo cáo y học: "Autoantibodies specific for apoptotic U1-70K are superior serological markers for mixed connective tissue disease" pdf
Báo cáo y học: "Autoantibodies specific for apoptotic U1-70K are superior serological markers for mixed connective tissue disease" pdf
... http://arthritis-research.com/content/7/2/R302
R302
Vol 7 No 2
Research article
Autoantibodies specific for apoptotic U1-70K are superior
serological markers for mixed connective tissue disease
Daniëlle Hof
1
, Kalok Cheung
1
, Dirk-Jan ... the E.F.G complex are more
specifically associated with SLE [7,8].
70K = U1-70K; 70K
apop
= apoptotic cleavage product of U...
Báo cáo Y học: Nuclear proteins that bind to metal response element a (MREa) in the Wilson disease gene promoter are Ku autoantigens and the Ku-80 subunit is necessary for basal transcription of the WD gene ppt
... were
incubated for 0.5, 4, 8, 12, 24, 30, 38 h and harvested in 200 lL lysis buffer. Whole-cell lysates (30 lg) were resolved by SDS/PAGE (10%
polyacrylamide), and immunoblotting was performed with ... were digested with 50 lL
70% formic acid at 37 °C for 48 h. The peptide fragments
generated by the formic acid treatment were lyophilized
completely and separated by electrophoresis. The Ku...
Báo cáo y học: "Allergen-specific T cell quantity in blood is higher in allergic compared to nonallergic individuals" pptx
... bone marrow, lymphoid and non-lymphoid
tissues like skin or mucosas. Th e non-blood tissues
might house the majority of allergen -specific memory
lymphocytes. So it is theoretically possible that ... cytokine production by carboxyfluorescein succinimidyl ester
dilution assay. Clin Exp Allergy 2006, 36:1538-45.
14. SS Tay, Clark AT, Deighton J, King Y, Ewan PW: T cell proliferation and
cytok...
Báo cáo y học: "Autoantibodies to low-density-lipoprotein-receptor-related protein 2 (LRP2) in systemic autoimmune diseases" pps
... Antilymphocyte antibodies and
systemic lupus erythematosus. Arthritis Rheum 1987, 30:225-
228.
4. Czyzyk J, Fernsten P, Shaw M, Winfield JB: Cell-type specificity
of anti-CD45 autoantibodies in systemic ... antilymphocyte antibodies, are often detected in the
sera of patients with systemic autoimmune diseases such
as systemic lupus erythematosus (SLE). Although the pres-
ence of antilymphoc...
Báo cáo y học: " Autoantibodies in vasculitis" pptx
... in
Otolaryngology: Proceedings of the First International Academic
Conference in Immunology and Immunopathology as applied to
Otology and Rhinology. Edited by Veldman JE, McCabe JE,
Huizing EH, Mygind ... by serum dilution is impossible if lympho-
cytes are absent. The use of HEp-2 cells for estimating
ANA levels, commonly set at a cutoff of 1:160, cannot be
compared with ANCA levels, whi...
Báo cáo y học: "Cartilage-specific autoimmunity in animal models and clinical aspects in patients – focus on relapsing polychondritis" ppsx
... cartilage and type II collagen in relapsing
polychondritis and other rheumatic diseases. Ann Rheum Dis
1981, 40:473-479.
12. Meyer O, Cyna J, Dryll A, Cywiner-Golenzer C, Wassef M, Rycke-
waert ... consisting mainly of neutrophils but also of lymphocytes, macrophages and
eosinophils. Hematoxylin and erythrosine staining. Reproduced with the permission of the American Society for Clinical In...
Báo cáo y học: "Autoantibodies in normals – the value of predicting rheumatoid arthrits" doc
... antibodies and IgM-RF
before the onset of RA. At a similar frequency, 10 of 16
patients who developed systemic lupus erythematosus or
mixed connective tissue disease were positive for
antinuclear antibodies ... 0.7–4.5 years before the onset of
symptoms [16]. In comparison, 82% of IDDM patients
have antibodies to glutamic acid decarboxylase 10 years
prior to the disease [17]. In the R...
Báo cáo y học: "Initial clinical trial of epratuzumab (humanized anti-CD22 antibody) for immunotherapy of systemic lupus erythematosu" ppt
... BILAG body stystem. Mean time to improvement (in days) of each BILAG body system during the follow-up of the
study (N denotes the number of patients available for analysis for each body system). ... activity at study entry
in each BILAG body system
Body system Number of
patients
Contributing signs/symptoms*
(number of patients)
I. General/
Constitutional
11 Fatigue/malaise/lethargy (1...
Báo cáo y học: "Relevance of the stroma and epithelial-mesenchymal transition (EMT) for the rheumatic diseases" docx
... in the synovium. Mast cells, important in
modifying ECM by elaborating proteases and tryptic
enzymes, are reviewed elsewhere [65]. Only in the past 10 to
15 years has the import of synovial fibroblasts, ... Cartilage 2003, 11:790-800.
88. Sakaguchi Y, Sekiya I, Yagishita K, Muneta T: Comparison of
human stem cells derived from various mesenchymal
tissues: superiority of synovium as a cell...
Báo cáo y học: "Autoantibodies against the replication protein A complex in systemic lupus erythematosus and other autoimmune diseases" pps
... preferentially rec-
ognize the phosphorylated form of RNAP II but are unreactive
with the unphosphorylated form of RNAP II [33]. In patients
with SSc, autoantibodies specific for the phosphorylated form
of ... has been shown that phophorylation is not nec-
essary for ribosomal P antigens to be recognized by autoanti-
bodies in SLE [35].
Both RNAP II and RPA are phosphorylated by exp...
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