Báo cáo y học: "Endothelin-1 in osteoarthritic chondrocytes

Báo cáo y học: "Aciculatin inhibits lipopolysaccharide-mediated inducible nitric oxide synthase and cyclooxygenase-2 expression via suppressing NF-B and JNK/p38 MAPK activation pathways" pot

... aciculatin (8-((2R,4S,5S,6R)-tetrahydro-4,5-dihydroxy-6-methyl-2H-pyran-2-yl)-5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-4H- chromen-4-one), one of main components of Chrysopogon aciculatis, by examining ... endoperoxide synthase and prostaglandin biosynthesis. FASEB J 1999, 13:1121-1136. 9. Kim SF, Huri DA, Snyder SH: Inducible nitric oxide synthase binds, S- nitrosylates, and activates...

Ngày tải lên : 10/08/2014, 05:21

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Báo cáo y học: "Endothelin-1 in osteoarthritic chondrocytes triggers nitric oxide production and upregulates collagenase production" pps

... osteoarthritis chondrocytesEffect of protein kinase inhibitors and LY83583 on endothelin-1 (ET-1)- induced MMP-13 and MMP-1 production by human osteoarthritis chondrocytes. Confluent monolayer chondrocytes ... ET-1-induced NO production was partially suppressed by the p38 kinase inhibitor and was completely suppressed by the protein kinase A kinase inhibitor KT5720 and by LY835...

Ngày tải lên : 09/08/2014, 06:22

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Báo cáo Y học: Variations in receptor site-3 on rat brain and insect sodium channels highlighted by binding of a funnel-web spider d-atracotoxin pdf

... speciﬁed in the ﬁgure legends. Equilibrium and kinetic analysis of binding The median inhibitory concentration (IC 50 ) values for the inhibition of toxin binding were determined by nonlinear regression ... The binding of 125 I-labelled d-ACTX-Hv1a to rat brain syna- ptosomes is inhibited c ompetitively by classical ScaTxs and allosterically by brevetoxin-1, similar to ScaTx binding. Ho...

Ngày tải lên : 08/03/2014, 16:20

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Báo cáo y học: " Decrease in expression of bone morphogenetic proteins 4 and 5 in synovial tissue of patients with osteoarthritis and rheumatoid arthritis" ppt

... purposes) lage by the release of inflammatory cytokines and destructive proteases [2]. Increases in knowledge about inflammatory cytokines and cytokine networks in chronic joint diseases has ... of BMPs in the lining and sublining layer. BMP-4 and BMP-5 are expressed in normal synovial tissue and were found decreased in OA and RA. This may suggest a role of distinct BMPs...

Ngày tải lên : 09/08/2014, 07:20

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Báo cáo y học: " Protein kinase A-dependent Neuronal Nitric Oxide Synthase Activation Mediates the Enhancement of Baroreflex Response by Adrenomedullin in the Nucleus Tractus Solitarii of Rats" pps

... adrenomedullin; ADMR: adrenomedullin receptor; GC: guanylate cyclase; Gs: stimulatory GTP-binding protein; nNOS: neuronal nitric oxide synthase; PKA: protein kinase A; PKG: protein kinase G. Yen et ... increase in protein levels of phos- pho-nNOS (Ser1416) in NTS. The ADM-induced increase in phosphorylation of nNOS at Ser1416 maximizedat30minandgradually declined within 60 min after...

Ngày tải lên : 10/08/2014, 05:21

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Báo cáo Y học: Amphibian peptides that inhibit neuronal nitric oxide synthase The isolation of lesueurin from the skin secretion of the Australian Stony Creek Frog Litoria lesueuri docx

... of nitric oxid e by nNOS. Nitric oxide has many roles in animals and plays important roles in t he nervous, muscular, cardiovascular and immune systems [68]. In anurans, nitric oxide is already ... from changes in enzyme velocities in the presence of increasing amounts of the peptides citropin 1.1 (A), lesueurin (B), caerin 1.9 (C)andfrenatin3 (D). Enzyme k inetics dat...

Ngày tải lên : 31/03/2014, 15:20

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Báo cáo y học: "T1-nerve root neuroma presenting with apical mass and Horner''''s syndrome" pps

... hand weakness and tingling in his fingers a few months later. During the subsequent two years following his initial traumatic episode, his hand weakness worsened, particu- larly in the winter and subsided ... exposure includes unilat- eral hemilaminectomy of the adjacent laminas and unilat- eral facetectomy for full exposure of the intraspinal and intraforaminal tumor [10], but co...

Ngày tải lên : 10/08/2014, 09:22

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Báo cáo y học: "Advanced glycation end products induce cell cycle arrest and proinflammatory changes in osteoarthritic fibroblast-like synovial cells" doc

... tissue into the synovium may play a role in the initiation and perpetuation of inflammation and degradation processes. RAGE as well as AGEs are present in the synovial lining, sublining and endothelium ... described by Zimmermann and col- leagues [20]. Briefly, synovial tissue was minced and digested at 37°C in PBS containing 0.1% trypsin for 30 minutes followed by 0.1% col...

Ngày tải lên : 09/08/2014, 14:22

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Báo cáo y học: "The epidemiology of intensive care unit-acquired hyponatraemia and hypernatraemia in medical-surgical intensive care unit"

... hyponatraemia and hypernatraemia are common in critically ill patients and are associated with increased risk of hospital mortality. Introduction Sodium disturbances, leading to hyponatraemia and hypernatraemia, ... (11%) patients and hypernatraemia in 2157 (26%) patients with an incidence density of 3.1 and 7.4 per 100 days of ICU admission, respectively, during 29,142 ICU ad...

Ngày tải lên : 25/10/2012, 10:31

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Báo cáo y học: " Effect of Weight Reduction on Cardiovascular Risk Factors and CD34-positive Cells in Circulatio"

... B12, and hCG for two days prior to beginning a 36-day very low calorie diet. This was followed by a 35 day maintenance period during which calorie in- take was gradually raised while restricting ... restriction in combination with the following: 1. Daily sublingual treatments by vitamin B12 (1,000 g per day). 2. Oral supplements consisting of the following nutrients: 250 mg tyro...

Ngày tải lên : 25/10/2012, 10:51

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Báo cáo y học: "Endothelin-1 in osteoarthritic chondrocytes triggers nitric oxide production and upregulates collagenase production" pps

Báo cáo y học: "Aciculatin inhibits lipopolysaccharide-mediated inducible nitric oxide synthase and cyclooxygenase-2 expression via suppressing NF-B and JNK/p38 MAPK activation pathways" pot

Báo cáo Y học: Variations in receptor site-3 on rat brain and insect sodium channels highlighted by binding of a funnel-web spider d-atracotoxin pdf

Báo cáo y học: "Aciculatin inhibits lipopolysaccharide-mediated inducible nitric oxide synthase and cyclooxygenase-2 expression via suppressing NF-B and JNK/p38 MAPK activation pathways" pot