Báo cáo y học: "Inhibition of antithrombin by hyaluronic acid may be involved in the pathogenesis of rheumatoid arthritis" potx
... pathogenesis of RA. The principal plasma inhibitor of thrombin is antithrombin, a single-chain 51 kDa glycoprotein that is synthesized in liver. The inhibitory activity of antithrombin on thrombin is ... presence of HA, supporting the notion that HA could compete with heparin for the heparin-binding region of antithrombin. Remarkably, HA affected the inhibition b...
Ngày tải lên: 09/08/2014, 06:22
... publication of this case report and any accompanying images. A copy of the written consent is available for review by the Editor -in- Chief of this journal. Acknowledgements The author expresses sincere ... histopathological examination of the mass. The author read and approved the final manuscript. Competing interests The author declares that the y have no competi...
Ngày tải lên: 10/08/2014, 23:21
... at the final stage of starch synthesis in the absence of concomitant amylopectin synthesis (reviewed in [41]). In vitro synthesis of amylose Because in Chlamydomonas amylose synthesis remains active ... rates of amylose synthesis and we can only state that the latter certainly does not exceed the rate of amylopectin synthesis. The increase in crystallinity wit- ne...
Ngày tải lên: 22/02/2014, 07:20
Báo cáo y học: "Indoleamine 2,3-dioxygenase-expressing dendritic cells are involved in the generation of CD4+CD25+ regulatory T cells in Peyer''''s patches in an orally tolerized, collagen-induced arthritis mouse model" ppt
... Hayaishi O: Regulation of indoleamine 2,3-dioxygenase activity in the small intestine and the epididymis of mice. Arch Biochem Biophys 1980, 203:343-351. 33. Malina HZ, Martin XD: Indoleamine ... approved by the Animal Research Ethics Committee at the Catholic University of Korea. Preparation of type II collagen Bovine CII was kindly provided by Professor Andrew Kang of...
Ngày tải lên: 09/08/2014, 10:22
Báo cáo y học: " High-mobility group box protein 1 (HMGB1): an alarmin mediating the pathogenesis of rheumatic disease." docx
... functions in vivo to enhance inflammation by binding PAMPs, DAMPs, and cytokines to promote dual- receptor interactions that may be especially effective because of their proximity. These receptors include ... consistently influenced by TNF blocking therapy with infliximab in nine studied RA patients [76]. These findings could suggest that HMGB1 acts upstream of TNF in the...
Ngày tải lên: 09/08/2014, 10:23
Báo cáo y học: "Rho kinase inhibitors Y27632 and H1152 augment neurite extension in the presence of cultured Schwann cells" pdf
... cones by increasing the net phos- phorylation of the myosin regulatory light chain. It also activates Rho kinase (ROCK) which directly phosphor- ylates the regulatory light chain of the major cytoplasmic myosin, ... H1152 altered the morphology of the SC. These changes were similar to those observed by Melendez et al [15]. They also described a shortening of the myel...
Ngày tải lên: 10/08/2014, 10:20
báo cáo khoa học: " Field transcriptome revealed critical developmental and physiological transitions involved in the expression of growth potential in japonica rice" potx
... autono- mously starts independent of the development of the sink, but is accelerated by the sink formation. Delaying leaf senescence in order to maintain the photosynthetic activity for as long ... for increasing the number of til- lers, one of the components of grain yield. The high demand for Pi during vegetative stage may be vital for proper development of...
Ngày tải lên: 11/08/2014, 11:21
Báo cáo y học: " Protein kinase A-dependent Neuronal Nitric Oxide Synthase Activation Mediates the Enhancement of Baroreflex Response by Adrenomedullin in the Nucleus Tractus Solitarii of Rats" pps
... the possibility that the activ ation of iNOS and eNOS may be involved in ADM-induced BRR-enhancing effect is deemed unlikely (Figure 1C &1D). Moreover, several lines of evidence support the ... activation by ADM and in NTS Since PKG can be activated by nNOS-derived NO [18], we next examined the role of PKG in the BRR enhance- ment response induced by AD...
Ngày tải lên: 10/08/2014, 05:21
Báo cáo y học: " HIV-1 neutralization by monoclonal antibody against conserved region 2 and patterns of epitope exposure on the surface of native viruses" pot
... results in the presence of highly immunogenic amino acids (His, Lys, Ala, Leu, Asp and Arg) within this epitope. These amino acids occur at a greater frequency than in the C1E pep- tides. The C2E ... [25-27]. Indeed, the epitopes around amino acids 93-112 and 218- 239 have been previously described, including epitopes at amino acids 90-100 of C1 and 222-231 of C2. Several MA...
Ngày tải lên: 11/08/2014, 08:21
Báo cáo Y học: Guanosine diphosphate-4-keto-6-deoxy-D-mannose reductase in the pathway for the synthesis of GDP-6-deoxy-D-talose in Actinobacillus actinomycetemcomitans potx
... extract was obtained by centrifugation at 20 000 g for 30 min at 4 °C. Binding of the fusion proteins to chitin beads via the intein/ chitin binding domain, cleavage of the fusion protein (in 20 m M Tris/HCl, ... content of 48.0% [43]. The GC content of the region essential for the biosynthesis of SPA in the other serotype strains (b–e) of A. actinomycetemcomita...
Ngày tải lên: 17/03/2014, 10:20