Báo cáo y học: "Tapasin gene polymorphism in systemic onset juvenile rheumatoid arthritis: a family-based case–control study" pot

... HLA -A1 , HLA-B8, HLA-DR3 haplotype, in at least one healthy Caucasian population [11]. Furthermore, using a large UK Caucasian sample, Ahmad and coworkers [12] recently reported that TPSN polymorphisms ... in systemic onset juvenile rheumatoid arthritis: a family-based case–control study Hulya Bukulmez 1,2,3,4 , Mark Fife 5 , Monica Tsoras 1 , Susan D Thompson 1 , Natal...

Ngày tải lên: 09/08/2014, 06:22

... serum amyloid A (SAA) [16]. Since SAA is a known biomarker of active SJIA [17], we compared the intensity of the 11.6-kDa peak with SAA levels in the sera, as determined by latex agglu- tination. As ... Medicine, Yokohama, Japan. All the patients were Asian and their mean age at the start of the study was 7.25 ± 0.92 years. Eight of them had obtained a clinical response to conventiona...

Ngày tải lên: 09/08/2014, 06:22

... psoriasis study analyzed a region previously identified by linkage in sibling pairs, and by thorough haplotype analysis narrowed it down to a single polymorphism (having excluded the remaining nine ... so far in humans include the RUNX1 protein previously known as AML 1a. AML 1a was originally identified because it is frequently involved in mutations and translocations associated...

Ngày tải lên: 09/08/2014, 01:23

... Medical Psychology, University of Navarra, Pamplona, Spain. 8 Child And Adolescent Psychiatry Unit, Department of Psychiatry, Valdecilla Universiy Hospital, Santander, Cantabria, Spain. 9 Department ... Yao JK, Reddy R, van Kammen DP: Abnormal age-related changes of plasma antioxidant proteins in schizophrenia. Psychiatry Res 2000, 97:137-151. 40. Machado-Vieira R, Andreazza AC, Viale CI, Z...

Ngày tải lên: 11/08/2014, 16:23

... 5’-GGAAGTGTTAGGGTTTGGTTTCT-3’ 60 capn4 5’-CCACAAGCTTTTGTTCTCTCAGTA-3’ 5’-CACAGGTACAGGGGAGAGGTTAC-3’ 60 pub 5’-TACTGACCGAGTGCTGAGACTACT-3’ 5’-GCAATTTGCCATATCAATAAAGAA-3’ 60 Northern blot analysis ... named 16S RNA most probably relates to the humanin gene [17], since its transcript contains poly (A) . According to our data (Tab. 5) a- myb was overexpressed in all AIDS-relate...

Ngày tải lên: 02/11/2012, 11:08

... (Qiagen, Valencia, CA, USA). The purity and concentration of RNA was determined by A 260/280 analysis and the RNA quality was analyzed by agarose gel electrophoresis. Affymetrix analysis Total ... microarray analysis may be a valuable tool for cloning arthritis controlling genes and improving our understanding of their biological pathways. Therefore, microarray analysis of animal models h...

Ngày tải lên: 09/08/2014, 01:23

... events. RNA and quantitative PCR In al l RNA isolatio ns, the total RN A quality w as assessed by using an Agilent 2100 Bioanalyzer (Agilent Technologies, Palo Alto, CA). RNA integrity numbers (RIN) ... types–makesthisapproach particularly appealing in the study of compensatory growth. In tissue-scale networks, any measura ble or quantifiable property can be considered a variable of...

Ngày tải lên: 12/08/2014, 13:22

... repairing ciga- rette smoke induced lung damage. This repair process appears inadequate in a subset of smokers, leading to gradually increasing parenchymal ECM destruction and emphysematous changes ... hand can affect this pathway by inhibiting phosphorylation of Smad2 and Smad3 and inducing ubiquination of their receptors. Additionally, Smad7 can induce TGFβ-production by fibroblasts upo...

Ngày tải lên: 12/08/2014, 14:20

... Hirai M, Tominaga N, Nakajima H, Elisseeva OA, Masuda T, Nakano A, Kawakami M, Oji Y, Ikegame K, Hosen N, Udaka K, Yasukawa M, Ogawa H, Kawase I, Sugiyama H: Wilms tumor gene peptide-based ... Manabu Kawa- kami 5 , Yoshihiro Oka 6 , Haruo Sugiyama 6 and Masuhiro Takahashi 1 1. Laboratory of Hematology and Oncology, Graduate School of Health Sciences, Niigata University, Niigata, .....

Ngày tải lên: 26/10/2012, 09:39

... Matsui T, Shimada K, Ozawa N, Hayakowa H, Hagiwara F, Nakyama H, Sugii S, Ozawa Y, Tohma S: Diagnostic utility of anti-cyclic citrullinated peptide antibodies for very early rheu- matoid arthritis. ... formed by post-transcriptional modification of arginine by peptidy- larginine deiminase [5]. Enzyme immunoassays (EIAs) based on synthetic cyclic citrullinated peptides (CCP2) are available fo...

Ngày tải lên: 09/08/2014, 01:22