Báo cáo y học: "Early and stable upregulation of collagen type II, collagen type I and YKL40 expression levels in cartilage during early experimental osteoarthritis occurs independent of joint location and histological grading" ppt

... upregulation of collagen type II, collagen type I and YKL40 expression levels in cartilage during early experimental osteoarthritis occurs independent of joint location and histological grading Helga ... increase inappropriate mechanical loading in many parts of the joint and, in keeping with this, col II and YKL40 expression ro...

Ngày tải lên: 09/08/2014, 06:22

... timing of the pain increases the PPV of the symptom "pain" to 75%, making it a much more useful piece of information in surgical planning. Potiential mechanisms of pain generation in ... some cases inhibit) the development of neuropathic pain in the setting of neuronal injury. This is of special significance to the present discussion given that a significant numb...

Ngày tải lên: 10/08/2014, 10:20

... association of this region in our rheumatoid arthritis family sample. Further investigation of this region, including detection and testing of all variants, is required to confirm rheumatoid arthritis ... SNPs in the sample investigated were in Hardy– Weinberg equilibrium in the control group. Test for association in RA trio families A total of 1,302 European individuals f...

Ngày tải lên: 09/08/2014, 14:20

... evidence of any inflammatory activity in their joints while they are off treatment. Persistence is the opposite of remission. There are problems in the literature regarding the definition of ... J, Eyre S, Symmons D, Worthington J, Silman A: Investigation of polymorphisms in the PADI4 gene in deter- mining severity of inflammatory polyarthritis. Ann Rheum Dis 2005, 64:1311-1...

Ngày tải lên: 09/08/2014, 08:22

... [13,15,18,28] in different intensity, but the factors determining the extent of insulin resistance are not known. Our observation that body mass index, which is certainly associated with insulin resistance ... patients were divided into three groups according to their primary admission diagnosis: i) sepsis (including severe sepsis and septic shock); ii) acute coronary syndrome (myocard...

Ngày tải lên: 25/10/2012, 10:02

... by imaging criteria. CT/MRI, which elegantly reveal the severity and location of the traumatic brain injury and the subsequent formation of a neoplasm at the same site, can provide convincing ... formation. Trauma probably acts as a cocarcinogen in the presence of an initiating carcinogen, i. e. it may induce the proliferation of in- itiated ” cells. Figure 1. MR...

Ngày tải lên: 25/10/2012, 11:48

... system. Redundancy is needed to maintain resiliency of a sys- tem. With diminishing redundancy, resiliency falters. In general, this is true in the early and latter phase of biologic entity’s ... complexity, and chaos with features of stability and instability, linearity and nonlinearity, bifurcation, attractor, etc., each constituting an impor- tant feature of one...

Ngày tải lên: 26/10/2012, 10:04

... lymphocyte proliferation in vitro [23]. Oral administration of You-Gui-Wan, a classical prescription of TCM containing AP, was shown to protect mice against hydrocoticoid-induced inhibition ... inhibition of IFN-γ, IL-2, IL-4 and IL-10 transcription [24]. In addition, vitamin B12, folinic acid and biotin identified in AP may also contribute to stimulated hematopoiesis [2...

Ngày tải lên: 02/11/2012, 10:19

... towards the design and synthesis of new molecules with higher binding affinity and enhanced stability against biological degradation and possibly biological activity. The impact of Aib introduction in the ... [47–49]. This limitation is imposed by the steric hindrance that arises from its gem-dimethyl group. The torsion angles for the main- chain conformation of Aib15 in the fa...

Ngày tải lên: 17/03/2014, 10:20

... number of disulphide bridges, the location of proline and arginine residues, and hydrophobic core interactions are generally recognized as key factors in determining the flexibility of the enzyme ... trilaurin, tripalmitin, tristearin and triolein, respectively. Fig. 5. Enzymatic activity of rPFL as a function of calcium concentra- tion. Fig. 2. Electrophoretic analysis sho...

Ngày tải lên: 24/03/2014, 04:21