Báo cáo y học: "A2B adenosine receptor activity is reduced in neutrophils from patients with systemic sclerosis" ppt
Báo cáo y học: "A2B adenosine receptor activity is reduced in neutrophils from patients with systemic sclerosis" ppt
... SSc.
Keywords: adenosine, A
2
adenosine receptors, neutrophils, receptor binding, systemic sclerosis
Introduction
Systemic sclerosis (SSc), also known as scleroderma, is a
connective tissue disease ... described in patients
with SSc, suggesting an alteration in adenosine control
mechanisms in this disease [16,17].
In the present study we analyzed A
2A
and A
2B
AR s...
Báo cáo y học: "Three novel beta-galactosidase gene mutations in Han Chinese patients with GM1 gangliosidosis are correlated with disease severity" ppsx
... transcript, leading to in- frame deletion of an
amino acid, p.Ser95del, in the elastin/laminin-binding
domain of EBP. This variation i n the elastin-binding
domain of the EBP protein may directly impair ... usually occurring within the first two years of
life. Cardiomyopathy is an atypical clinical feature in
some Caucasian patients with infantile GM1 gangliosido-
sis. The residual...
Báo cáo y học: "Vitamin D receptor gene BsmI polymorphisms in Thai patients with systemic lupus erythematosus" potx
... clinical manifestations or laboratory
profiles. In our study, the BB genotype is low in both 194
healthy controls and 101 patients with SLE. However, this is
in accordance with previous findings ... arthritis [4] and rheuma-
toid arthritis [5].
Polymorphism of the vitamin D receptor (VDR) gene was
found to be associated with many diseases, including oste-
oporosis [6], hyp...
Báo cáo khoa học: Protein kinase Ch activity is involved in the 2,3,7,8tetrachlorodibenzo-p-dioxin-induced signal transduction pathway leading to apoptosis in L-MAT, a human lymphoblastic T-cell line potx
... apoptosis.
TCDD induces nPKC kinase activity in L-MAT
cells
To establish whether TCDD increases nPKC kinase
activity, we examined nPKC kinase activity by using
PKCh pseudo-substrate, which is preferentially ... induced by TCDD was com-
pletely inhibited in the presence of 20 lm myr-PKCh
PPI, as shown in Fig. 4, confirming the involvement of
nPKCs.
PKCh kinase activity is compl...
Báo cáo y học: "Comparative responses to nasal allergen challenge in allergic rhinitic subjects with or without asthma" potx
... the pathophysiology of allergic rhinitis or its relationships
with asthma.
Trial registration: ClinicalTrials.gov NCT01286129
Background
Asthma and rhinitis are two airway inflammatory dis-
eases ... response in this study.
Conclusions
This study shows that multiple nasal challenges with
perennialallergensinducemorerhinorrheainrhinitic
subjects without asthma and more nasal obstruction...
Báo cáo y học: "Voxel-based structural magnetic resonance imaging (MRI) study of patients with early onset schizophrenia" potx
... positive symptoms.
This may be intriguing in view of the evidence, from a pos-
itron emission tomography (PET) study, showing dysreg-
ulation of dopaminergic transmission in the midbrain in
schizophrenia ... be
significantly correlated with the reduced GM volume in
the bilateral posterior cingulate gyrus, with the increased
WM volume in the cerebellum (vermis region), and w...
Báo cáo y học: "A cohort study of accidents occurring in mentally handicapped patients living in institutions" pot
... detect and/or treat predisposing factors
such as vitamin D deficiency, which is commonly found
in this type of patient.
The majority of the 1,497 minor injuries consisted of
bruising (40%), wounds ... Ozanne-Smith J: Injury risk in young people with
intellectual disability. J Intellect Disabil Res 2002, 46:6-16.
10. Konarski EA, Sutton K, Huffman A: Personal characteristics associate...
Báo cáo y học: "Local hyperhemia to heating is impaired in secondary Raynaud''''s phenomenon" pptx
... 0.06).
Discussion
Our study shows that hyperhemia to local heating is dramati-
cally altered in terms of kinetics and amplitude in patients with
SSc in comparison with patients with primary RP, ... prospectively discriminate
those patients presenting with RP who will develop clinical
signs of connective tissue diseases. We are also planning a
study to include patients...
Báo cáo y học: "Cartilage oligomeric matrix protein is involved in human limb development and in the pathogenesis of osteoarthriti" pptx
... defect from patients in the late stages of
OA, an increase in staining intensity was found in the pericel-
lular space (Figure 4b). In healthy cartilage, COMP staining
was also found in the territorial ... observed with COMP in other
instances. The smear in the blot of healthy cartilage tissue (Fig-
ure 2, lane 3) probably results from the high aggrecan content,
which i...
Báo cáo y học: " Synovial fluid leukocyte apoptosis is inhibited in patients with very early rheumatoid arthriti" pdf
... 2
Synovial fluid neutrophil and lymphocyte apoptosis in patients with very early inflammatory arthritisSynovial fluid neutrophil and lymphocyte apoptosis in patients with very early inflammatory ... 1
Apoptotic lymphocytes and neutrophils in synovial fluid cytospin preparations from patients with very early inflammatory arthritisApoptotic lymphocytes and neutrophils i...