... K, Itoh K, IshiyamaS, Saito S, Inoue K, Kamatani N, Gillespie MT, Martin TJ, Suda T:IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis. ... synoviocytes in rheumatoid arthritis. Arthritis Rheum 2000, 43:259-269.37. Shigeyama Y, Pap T, Kunzler P, Simmen BR, Gay RE, Gay S:Expression of osteoclast differentiation factor in rheumatoid arthritis. ... that a therapeutic vaccine approach targetingRANKL may be useful for inhibiting bone destruction in avariety of pathological bone diseases.Inhibitory cytokines produced by T cells onosteoclast...