Báo cáo y học: "MMP-3 expression and release by rheumatoid arthritis fibroblast-like synoviocytes induced with a bacterial ligand of integrin α5β" pdf

... Yli-Jama T, Jal- ava J, Vainio O, Toivanen P: Bacterial components in the syno- vial tissue of patients with advanced rheumatoid arthritis or osteoarthritis: analysis with gas chromatography-mass ... (RA) and osteoarthritis (OA) fibroblast-like synoviocytes (FLSs)Gene expression patterns in rheumatoid arthritis (RA) and osteoarthritis (OA) fibroblast-like synovioc...

Ngày tải lên: 09/08/2014, 06:22

... promoter TGA AGC TGG AAA CCA TCA TTC AAA ACA TTA GCA GGA ATT TTC 52 343 Lower promoter GGA GTT CTG CCA GGG AAC CAC GAC AGG GGA GAA CGC CAC TTA 57 587 Exon 1 GTG CTG CCT GAG AAG GAT TG GAA AGT GCC ... exactly with the mobilities of di-, mono- and unglycosylated forms of recombinant cystatin F previously characterized by enzymatic removal of N-linked carbohydrate and carbohydrate...

Ngày tải lên: 21/02/2014, 01:21

... cytoplasmic fraction (20 lg, lane 1) and of CCT purified from rabbit reticulocyte lysate (2 lgand6lg in lanes 2 and 3, respectively). Lanes 1 and 2 were Western blotted and immunostained by an ... CCT were quantitated by the use of a phosphori- mager and expressed as a fraction of the maximum amount of bound labeled tubulin and plotted as a function of the ratio...

Ngày tải lên: 23/03/2014, 21:20

... recombinant NaoA after DEAE-Sepharose Fast Flow chromatography; lane 6, standard molecular mass markers (phosphorylase b,97kDa;BSA,66kDa; ovalbumin, 45 kDa). Fig. 3. Assay of NaoA activity. (A) Protein ... NaoA was determined from a standard curve of pI and migration distance (cm) of protein standards. Enzyme assay and analytical methods E. coli BL21(DE3) containing plasmid pNA101...

Ngày tải lên: 31/03/2014, 08:20

... This paw was designated as acute arthritic (AA), and contralateral or ipsilateral paws that were Arthritis Research & Therapy Vol 7 No 2 Adarichev et al. R199 with cartilage PG, and live lymphocytes ... course of the adoptively transferred arthritis, RNA was isolated from pre-arthritic paws (PA) and diseased paws (AA and CA) (Table 1). In addition, RNA was isolated from nor...

Ngày tải lên: 09/08/2014, 06:22

... (tetrasaccharides and hexasaccharides of hyaluronate and heparan sulphate) [39-41]. Interestingly, all known carbohydrate TLR ligands fall into the category of oli- gosaccharides generated by endoglycosidases, ... in arthritis patients' syno-vial membrane and fibroblast samplesHc-gp 39, HexA and HexB gene expression in arthritis patients' syno- vial membrane and...

Ngày tải lên: 09/08/2014, 14:20

... 5'-CACAGTGAGGAATGTCCACAAAC 5'-6-FAM-TCGGCAAACCTAGTGTGCTATGCCTAAGCA-TAMRA TNF-α 5'-CCAGGTTCTCTTCAAGGGACAA 5'-CTCCTGGTATGAAATGGCAAATC 5'-6-FAM-CCCGACTATGTGCTCCTCACCCACA-TAMRA GRO1 ... 5'-6-FAM-TTCTATGCGCGGGGGCGGAA-TAMRA CD3 5'-GGATGGAGTTCGCCAGTCAA 5'-GGTTTCCTTGGAGACGGCTG 5'-6-FAM-ACAGGTCTACCAGCCCCTCAAGGACCG-TAMRA Ubiquitin 5'-CGAGAACGTGAAGGCCAAG...

Ngày tải lên: 09/08/2014, 06:22

... scores by age, gender and study groupAdjusted mean visual analog scale pain scores by age, gender and study group. Significant increases in pain scores for female and male community controls and ... pro- duce covariate-adjusted mean VAS pain by exercise group and by study year for statistically significant predictors that y yy t t tt = + ∈ −1 2 , Available online http:/ /...

Ngày tải lên: 09/08/2014, 07:20

... combination of the T variant and HLA- SE (OR = 7.85). The PTPN22 1858T variant was associated with future development of RA. There was an association between the T variant and anti-CCP antibodies and ... was significantly associated with carriage of the T variant and there was a greatly increased relative risk for the development of RA Available online http:/ /arthritis-...

Ngày tải lên: 09/08/2014, 07:20

... frequency-matched by gender and birth year were randomly selected from the Danish population by means of the Civil Registration System, a national database that keeps track of all demographic changes ... birth year, and year or pseudo-year of RA diagnosis. b Adjusted for gender, birth year, year or pseudo-year of RA diagnosis, place of residence, educational status, hist...

Ngày tải lên: 09/08/2014, 08:22