Báo cáo y học: "Relaxin''''''''s induction of metalloproteinases is associated with the loss of collagen and glycosaminoglycans in synovial joint" ppsx
Báo cáo y học: "Relaxin''''s induction of metalloproteinases is associated with the loss of collagen and glycosaminoglycans in synovial joint" ppsx
... [39].ConclusionsRelaxin causes the targeted induction of collagenase-1 and stromelysin-1 in synovial joint and pubic symphysis fibro-cartilages but not in articular cartilage. This induction of MMPs in joint ... the amount of collagen in fibrocartilaginous tissues from different sites, including the pubic symphysis and synovial joints. These findings alsosuggest that in fibrocartilaginous tissues, including ... properties and the ability of joint tissues to func-tion normally, this modulation of MMPs and resulting matrix loss in the fibrocartilaginous TMJ disc by relaxin mightexplain the distinct age and...
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Báo cáo y học: " High sensitivity C-reactive protein is associated with lower tibial cartilage volume but not lower patella cartilage volume in healthy women at mid-life" pdf
... of the data. RB was responsible for analysis and interpretation of the data. AW performed data analysis. FC and SDavis were responsible for study design and data analysis and interpretation and ... This should be further assessed by alongitudinal study.IntroductionOsteoarthritis (OA) is a major cause of morbidity, affecting60% of men and 70% of women over the age of 65 years [1]. In ... wereexcluded if they had had any of the following: a clinical diagno-sis of knee OA as defined by American College of Rheumatol-ogy criteria, knee pain lasting for > 24 h in the last 5 years, aprevious...
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Báo cáo y học: "α Anti-α-fodrin antibodies do not add much to the diagnosis of Sjögren’s syndrome" pot
... autoimmuneexocrinopathy of unknown origin. Therefore the diagnosis of SjS, in the absence of a gold standard, is based on cri-teria containing a number of subjective and objectivesigns and symptoms. In the ... indicating a disease sensitivity of IgG anti-bodies against α-fodrin of 48%. Nine (43%) of the 21 primary SjS sera were found to contain IgA antibodiesagainst α-fodrin (Table 1) and 3 (14%) of the ... A blinded set of serum samples was therefore analyzed in Hanover.ResultsAnalysis for anti-αα-fodrin, anti-La, and anti-Ro60 by ELISAUsing the purified α-fodrin–GST protein encoded by the cDNA...
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Báo cáo Y học: Amphibian peptides that inhibit neuronal nitric oxide synthase The isolation of lesueurin from the skin secretion of the Australian Stony Creek Frog Litoria lesueuri docx
... with Ca2+calmodulin, they should also inhibit the activity of calcineurin. The four model peptides lesueurin, citropin 1.1,frenatin 3 and caerin 1. 9, all inhibit the activity of calcineu-rin, but at ... the presence of increasing concentrations of Ca2+calmodulin, the inhibition dropped by 50% in each case. In addition,these peptides also inhibit the activity of calcineurin, anotherenzyme that ... to inhibit nNOS by displacingCa2+calmodulin from the calmodulin b inding domain of nNOS. In this p rocedure, the nNOS inhibition experimentswere carried out with citropin 1.1, frenatin 3, and...
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Báo cáo y học: "A second-generation autologous chondrocyte implantation approach to the treatment of focal articular cartilage defects" ppsx
... biochemicalcharacteristics, is poorly organized, contains significantamounts of collagen type I, and is susceptible to injury. The breakdown of this inferior repair tissue with time and loadingeventually leads ... developing three-dimensional constructs using native and synthetic biomaterials. Clinically significant and satisfactory resultsfrom applying autologous chondrocytes seeded in fibrin within abiodegradable ... reportedhave included periosteal hypertrophy, ablation, uneven celldistribution, and loss of cells into the joint cavity [15,16],resulting in repetition of surgery in up to 25% to 36% of patients...
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Báo cáo y học: "What magnetic resonance imaging has told us about the pathogenesis of rheumatoid arthritis - the first 50 years" doc
... autonomous of inflammation[5]. At the dawn of the era of biological therapy in RA, thistheory led to the concept of a dual-therapeutic strategy,including anti-inflammatory biological therapy, on ... final common pathway of an array of inflammatory, crystal, and degenerative arthritis. The advan-tage of seeing patients early in the course of disease is thatabnormalities evident in imaging ... autoantibody- associated RA is primarily a disorder of synovium. Thisemphasises the importance of the effective treatment of synovitis as being the only necessary and sufficient thera-peutic...
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Báo cáo y học: "Dual energy x-ray absorptiometry analysis contributes to the prediction of hip osteoarthritis progression" pdf
... participated in the design of the study, analysis of DXAimages, performed the statistical analysis and drafts the man-uscript. JL conceived the study and elaboration of the programused to analyse the ... of the various models. R is a programming lan-guage and open source software environment for statisticalcomputing and graphics widely used for data analysis. AIC is an index of the amount of ... middle of the femoral neck, bisect-ing the centre of the neck. The femoral axis was determined asa line parallel to the femoral shaft passing through the middleArthritis Research & Therapy...
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Báo cáo y học: "Retinoic acid induces HL-60 cell differentiation via the upregulation of miR-663" docx
... properly cited. and plays a key role in OS-induced inflammatoryresponses by mediating the expression of inflammatorygenes in HUVECs [33]. Downregulation of miR-663 in tumor cells may contribute ... arrest and induction of differentiation of HL-60 cells in response to Sch 52900 is due to induc-tion of the cell cycle inhibitor p21WAF, and inhibition of the extracellular signal-regulated kinase ... miR-663,whichisofinterestasTBF-b is an important molecule with roles in many signaling pathways. These findingsindicate miR-663 expression is upregulated duringATRA-induced differentiation, and lentivirus...
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Báo cáo khoa học: Comparative proteomic analysis identifies proteins associated with the development and progression of colorectal carcinoma pot
... electro-phoresis ⁄ MS and immunohistochemistry in combina-tion, the aim of this study was to investigate the genesis- and metastasis -associated proteins, and toKeywordscarcinogenesis; colorectal carcinoma;proteomics; ... byextracting Rho family GTPases from membranes and solubilizing them in the cytosol. Moreover, they interactonly with prenylated Rho proteins both in vitro and in vivo [11,12]. They also inhibit ... S100A9 and LASP-1 may play animportant role in the development and progression of CRC. Further functional and clinical analysis of the proteins is necessary to elucidate their precise role in the...
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Báo cáo khoa học: Direct CIII–HflB interaction is responsible for the inhibition of the HflB (FtsH)-mediated proteolysis of Escherichia coli r32 by kCIII docx
... have any role in the proteolysis of substrateslike SecY or YccA by HflB. We think that the primaryrole of CIII is associated with k lysogeny. In thisrespect, the antiproteolytic activity of CIII ... substrates. The relative binding affinityfor r32–HflB interaction and CIII–HflB interactionwould play an important role in the inhibition of proteolysis of r32by HflB.Interestingly, both CII and r32are ... interaction.Results In vitro proteolysis of r32by HflB requires ATP The proteolysis of r32by HflB is very rapid and requires the DnaK–DnaJ–GrpE chaperone machine in vivo [18–20]. However, this proteolysis is...
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Từ khóa: báo cáo y họcbáo cáo y học cổ truyềnmẫu báo cáo y học cổ truyềnbao cao y hoc colchicinphan ban luan trong bao cao y hoc co truyenschuam apos s outline of theory and problems in advanced calculuswhat indian tribe is associated with the trail of tearsis associated with the therapeutic benefits of immunotherapyphenotype freeze tolerance is associated with the differential expression of the aquaporin gene aqy2cytokines chemokines and growth stimulating factors is associated with the depletion of tia proteinsbáo cáo khoa học y họcbáo cáo y tế học đườngmẫu báo cáo y tế học đườngbáo cáo y tế học đường cuối nămbáo cáo y tế học đường năm 2012Báo cáo thực tập tại nhà thuốc tại Thành phố Hồ Chí Minh năm 2018chuyên đề điện xoay chiều theo dạngNghiên cứu tổ chức pha chế, đánh giá chất lượng thuốc tiêm truyền trong điều kiện dã ngoạiNghiên cứu vật liệu biến hóa (metamaterials) hấp thụ sóng điện tử ở vùng tần số THzGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANPhối hợp giữa phòng văn hóa và thông tin với phòng giáo dục và đào tạo trong việc tuyên truyền, giáo dục, vận động xây dựng nông thôn mới huyện thanh thủy, tỉnh phú thọPhát triển mạng lưới kinh doanh nước sạch tại công ty TNHH một thành viên kinh doanh nước sạch quảng ninhPhát triển du lịch bền vững trên cơ sở bảo vệ môi trường tự nhiên vịnh hạ longNghiên cứu, xây dựng phần mềm smartscan và ứng dụng trong bảo vệ mạng máy tính chuyên dùngĐịnh tội danh từ thực tiễn huyện Cần Giuộc, tỉnh Long An (Luận văn thạc sĩ)Thơ nôm tứ tuyệt trào phúng hồ xuân hươngQuản lý nợ xấu tại Agribank chi nhánh huyện Phù Yên, tỉnh Sơn La (Luận văn thạc sĩ)Tăng trưởng tín dụng hộ sản xuất nông nghiệp tại Ngân hàng Nông nghiệp và Phát triển nông thôn Việt Nam chi nhánh tỉnh Bắc Giang (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtTrách nhiệm của người sử dụng lao động đối với lao động nữ theo pháp luật lao động Việt Nam từ thực tiễn các khu công nghiệp tại thành phố Hồ Chí Minh (Luận văn thạc sĩ)Đổi mới quản lý tài chính trong hoạt động khoa học xã hội trường hợp viện hàn lâm khoa học xã hội việt nam