... Rheumatology and Clinical Immunology, Department of Internal Medicine, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya, Hyogo 663-8501, Japan2Division of Hematology, Department of Internal ... were maintained in a pathogen-free facility at the Hyogo College of Medicine (Nishinomiya, Hyogo, Japan).Animal experiments were performed in accordance with the guidelines of the National Institutes ... to have major roles in fibrinogenesis in animal models [19-23]. To clarify whethermodulation of IL-4 and TGF-β has a role in the prevention of sclerosis induced by HGF gene transfection in the...