Báo cáo y học: "γ Paradoxical roles of IFN-γ in models of Th1-mediated autoimmunity" potx

... demonstrated in the analysis of the role of IFN-γ in models of autoimmunity. Early attempts to define the role of IFN-γ in autoimmunity by the adminis- tration of IFN-γ or neutralizing antibodies ... simplistic, especially as it pertains to the role of IFN-γ. Keywords: arthritis, autoimmunity, cytokines, IFN-γ Commentary Paradoxical roles of IFN- γγ in m...

Ngày tải lên: 09/08/2014, 06:22

... (1979) So lid phase synthesis without repetitive hydrolysis. Preparation o f leucylalanyl-glycyl- valine using 9-fluorenylmethyloxy- carbonylamino acids. Int. J. Peptide Protein Res. 13, 35–42. 27. ... Bal 1,2 1 Faculty of Chemistry, University of Wroclaw, Poland; 2 Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland A comparative study of thermodynam...

Ngày tải lên: 22/02/2014, 04:20

... against looking at each step of the programme independently for example paying attention to individual variables such as number of women who received counseling, of those who received counseling ... shortcomings and the need for this is further highlighted by the findings of this study. The limitations of this study were that the data was only collected from the women's point...

Ngày tải lên: 10/08/2014, 05:20

... within inflamed joints appears to be reg- ulated not only by inflammatory cytokines but also by the physical interaction of activated leukocytes with FLSs. Once expressed, IP-10 probably plays ... significantly inhibited IP-10 induction. These results suggest that IP-10 expression within inflamed joints appears to be regulated not only by inflammatory cytokines but also by the physical inte...

Ngày tải lên: 09/08/2014, 01:21

... perhaps changing, roles in the overall patho- genesis of this form of arthritis. In the light of the findings presented by Kim and colleagues [1], it is interesting that a small number of studies have ... disease severity [5]. In another study, EAE failed to resolve in TNFα -/- or TNFR -/- mice, suggesting that TNFα plays an important role in resolution of inflammation [...

Ngày tải lên: 09/08/2014, 10:23

... strongly implicated in the inflammatory stages of RA. Inflammatory cells infiltrate the synovial sublining and produce proinflammatory cyto- kines, chemokines, and growth factors that stimulate synovial lining ... IKKγ). Phosphorylation of IκB by the activated IKK complex is predominantly by IKKβ. This triggers lysine 48 (K48)-linked polyubiquitination at adjacent lysine residues initia...

Ngày tải lên: 09/08/2014, 10:23

... localization by hematoxylin-eosin stain, immunohistochemistry, polymerase chain reaction and In- situ hybridization Results: Hyaline-vascular type was diagnosed in 18 cases, plasma cell type in 1 and ... mainly in inter-follicular areas. There are 12 cases having EBER signal in areas of germinal centers and 6 cases having signals in inter-follicular areas. In the group of EBV...

Ngày tải lên: 10/08/2014, 10:20

... using original length of stay data and 2003 nursing day prices. Subsequently, total individual costs of care during the first six months were computed by holding the original ratio between inpatient ... central point representing a cost sav- ing of € 5,990 and a QALY gain of 0.51. The point esti- mate for the ICER is €11,685 saved per QALY gained; €14,211 and €7,745 saved per QALY gai...

Ngày tải lên: 25/10/2012, 10:35

... Int. J. Med. Sci. 2011, 8 http://www.medsci.org 468 copy owing to incomplete bowel preparation. The bleeding was controlled by #3-0 Vycryl intracorporeal suture, and the invagination of ... Moreover, invagina- tion of diverticulum can be easily performed using laparoscopy with a simple suture technique. There- fore, we decided to invaginate the diverticulum in- stead of using...

Ngày tải lên: 25/10/2012, 10:51

... twin. Lancet. 1999; 354: 1445-6. 9. Nigro MA, Wishnow R, Maher L. Colpocephaly in identical twins. Brain Dev. 1991; 13: 187-9. 10. Yager J. Asymmetry in monozygotic twins. Am J Psychiatry. ... Wester K. Monozygotic twins with mirror image cysts: indication of a genetic mechanism in arachnoid cysts? Neurology. 2007; 69: 110-1. 12. Springer S, Searleman A. Laterality in twins: t...

Ngày tải lên: 25/10/2012, 11:00