Báo cáo khoa học: "Comparison of immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH) assessment for Her-2 status in breast cancer" ppsx
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Comparison of immunohistochemistry (IHC) and fluorescence in
situ hybridization (FISH) assessment for Her-2 status in breast
cancer
Weiguo Sui
†1
, Minglin Ou
†1,2
, Jiejing Chen
†1
, Youhua ... Yeh KT, Lee DJ, Yin PL, Chen
M: Comparison of immunohistochemical and fluorescence in
situ hybridization assessment for HER-2/ neu...
... specific interactions can
be outlined. The residues in the ligand-binding sites in
Fig. 6. (A) A front overview of the P-gp binding cavity with the
inhibitors QZ59-RRR and QZ59-SSS (in space-filling form) ... observation is supported by docking of the QZ59 ligands
into human P-glycoprotein, thus aiding in the understanding of the com-
plex behavior of P-glycoprotein substrates...
...
a
can be decomposed in the
3.2 Training
During training, we proceed over all sentence pairs
and estimate the probabilities by determining the
relative frequencies of applying an alignment tem-
plate. ... ratio of the sum
of deleted, inserted, and substituted concepts
w.r.t. a Levenshtein-alignment for a given ref-
erence concept-string, and the total number
of concepts i...
... ex-
periment, oxygen and normal saline were supplied con-
tinuously, and anesthesia was maintained with an addi-
tional infusion of midazolam. Continuous ECG monitor-
ing was performed in order to confirm ... placed
in the left carotid artery after achieving local anesthesia
with 2% lidocaine, and a cutdown was made. After infus-
ing 10,000 units of heparin, a 7 Fr. coronary ar...
... phase
(buffer A) containing 0.1% formic acid in water and an
organic mobile phase (buffer B) containing 0.1% (v ⁄ v)
formic acid in acetonitrile. Desalting of the samples was
performed for 1.5 min with 99% ... for CLDN3 and CLDN4 proteins,
and binding of the toxin to these claudins leads to
rapid cytolysis of cells [26]. Preclinical studies have
suggested that Clostridium...
... level of the
Spc1 MAP kinase. Induction of ctt1, encoding catalase, and apt1, encoding
a 25 kDa protein, but not that of gpx1, encoding glutathione peroxidase,
was indistinguishable in four ubiquinone-deficient ... Whereas induction of ctt1
+
and apt1 occurred in
all ubiquinone-deficient strains, induction of gpx1
+
was not observed in any of the tested strains (Fig. 6).
H...
... Boxed
amino acid residues are those involved in
substrate binding by side chain–side chain
interactions, and part of a g iven subsite is
indicated by the numbers under the boxes
(i.e. 1, S
1
binding ... (peptide 5 in Table 1) gave
rise to a 10-fold increase in K
m
and a corresponding
decrease in k
cat
⁄ K
m
, underscoring the importance of
the interactions between the Tyr OH...
... be obtained
in the MALDI-TOF ⁄ MS spectrum. We could not
obtain any information about the ice-binding ability of
the glycan part of AnpAFP. Direct involvement of gly-
can in ice binding has been ... carrots [27] and for
aCa
2+
-dependent species of fish type II AFP [28].
There is no involvement of glycans in ice binding of
these proteins because no significant change in...