... malignant gastrointestinal stromal tumor with positive CD117 (c-kit) staining, and negative margins ofresection, and no continuity of tumor with the sigmoid colon. Due to the malignant and aggressivenature ... on immunohisto-chemistry. Gastrointestinal stromal tumors can appear anywhere in the gastrointestinal tract, from the mouth to the anus, butalso in extra -gastrointestinal locations such as mesentery,omentum, ... malignant or at least an aggressive extra -gastrointestinal stromal tumor (Fig 3).Immunostainings for LCA, CD117, CD34, pancytokera-tin, s100, smooth muscle actin, calretinin, EMA, vimen-tin,...