... The crystal struc- ture of a proteinase K-like enzyme from a psychrotroph Serratia species has been solved to 1.8 A ˚ . The structure has been compared with the struc- tures of proteinase K from ... Journal 273 (2006) 6171 ê 2005 The Authors Journal compilation ê 2005 FEBS The 1.8 A ˚ crystal structure of a proteinase K-like...
Ngày tải lên: 19/02/2014, 07:20
... thaliana proteins also contain a PAC motif, and conversely that all PAC- annotated A. thaliana proteins contain a PAS domain. Therefore, in the case of A. thaliana,thePASandPAC motifs are inseparable, ... that not all six structures contain a PAS as well as a PAC motif, according to the PFAM database (Fig. 1D and Table 1). Each of the 958 PAS domains was modelled a...
Ngày tải lên: 19/02/2014, 12:20
Tài liệu Báo cáo khoa học: Guanidinium chloride- and urea-induced unfolding of FprA, a mycobacterium NADPH-ferredoxin reductase Stabilization of an apo-protein by GdmCl docx
... summarizes the urea-induced changes in func- tional and structural properties of FprA as studied by changes in enzymatic activity, FAD and tryptophan fluorescence and CD ellipticity at 222 nm at ... equilibrium unfolding of FprA in urea and GdmCl suggests dramatically different pathways and mechanism for the two denaturants as summarized in Fig. 6. The urea-induced unf...
Ngày tải lên: 19/02/2014, 16:20
Tài liệu Báo cáo khoa học: Experimental proof for a signal peptidase I like activity in Mycoplasma pneumoniae, but absence of a gene encoding a conserved bacterial type I SPase pdf
... the asparagine in position 26 was labeled within the intact protein at its a- amino group and represents the amino terminal amino acid of P40. The efficiency of this reaction was quite high, as ... 4549–4580. I. Catrein et al. Signal peptidase I activity in M. pneumoniae FEBS Journal 272 (2005) 28922900 ê 2005 FEBS 2899 Experimental proof for a signal peptidase...
Ngày tải lên: 19/02/2014, 18:20
Báo cáo khoa học: Xenopus Rbm9 is a novel interactor of XGld2 in the cytoplasmic polyadenylation complex pptx
... may mediate the enhancing effect of splicing on mRNA translation [34–36]. Rbm9, as a splicing factor interacting with a PAP, may also participate in the translational enhancement mediated by introns. Indeed, ... localization of mammalian Rbm9 is unclear and is dependent on the isoform and the tissue examined; however, it appears to be mainly nuclear in cell lines an...
Ngày tải lên: 07/03/2014, 05:20
Báo cáo khoa học: Enhanced peptide secretion by gene disruption of CYM1, a novel protease in Saccharomyces cerevisiae doc
... been investigated. Intracellular synthesis of CCK-22 was decreased in a cym1D0 strain accompanied by a n increased concentra- tion of proCCK. In contrast, the fraction of extracellular CCK-22 was ... peroxidase and a dinamin-like GTPase, and is required for maintenance of mitochondrial morphology and DNA [45,46]. Whether disruption of CYM1 in uences the ability to mai...
Ngày tải lên: 07/03/2014, 16:20
Báo cáo khoa học: "Creative Language Retrieval: A Robust Hybrid of Information Retrieval and Linguistic Creativity" pot
... non-literal matching and automatic query expansion. 3 Creative Text Retrieval In language, creativity is always a matter of con- strual. While conventional IR queries articulate a need for information, ... explore how an IR system can itself provide a degree of creative anticipation, acting as a mediator between the lit- eral specification of a meaning and the retriev...
Ngày tải lên: 07/03/2014, 22:20
Báo cáo khoa học: "GAMR VIEWED AS A FUNCTIONING PART OF A COGNITIVES SERM A YTM" pot
... meanings, grammar, and pragmatic or local context, receive support as separately definable knowledge within studies of aphasia. There is a vast literature concerning what aspects of language are indepen- ... mean several things simultaneously. An example related to the grammatical representation is that the syntactic category aspect of each meaning of a phonetic word is...
Ngày tải lên: 08/03/2014, 18:20
Báo cáo khoa học: "Lexical surprisal as a general predictor of reading time" potx
... for Computational Linguistics Lexical surprisal as a general predictor of reading time Irene Fernandez Monsalve, Stefan L. Frank and Gabriella Vigliocco Division of Psychology and Language Sciences University ... psychological accu- racy of each model (χ 2 (2) values) plotted against its linguistic accuracy (i.e., its quality as a lan- guage model, measured by the negati...
Ngày tải lên: 08/03/2014, 21:20
Báo cáo khoa học: Oxidative stress induces a reversible flux of cysteine from tissues to blood in vivo in the rat pptx
... disulfide bal- ance of these organs, and whether cysteine efflux to the blood was paralleled by a change in the Cys concentration in other tissues. Diamide, at 60 min from the start of administration, ... increase in the concentration of total cysteine showed an almost linear dose dependence, as shown in Fig. 6, in which the maximum total cysteine accumu...
Ngày tải lên: 16/03/2014, 02:20
Báo cáo khoa học: Isolation, characterization, sequencing and crystal structure of charybdin, a type 1 ribosome-inactivating protein from Charybdis maritima agg. potx
... purification, character- ization and structural analysis of charybdin, a novel 29-kDa type 1 ribosome-inactivating protein, from bulbs of the white variety of C. maritima agg. Results Charybdin was ... crystallography. Acta Crystallogr D Biol Crystallogr 50, 760–763. 22 Navaza J (19 94) AmoRe: an automated package for molecular replacement. Acta Crystallogr A 50, 15...
Ngày tải lên: 16/03/2014, 14:20
Báo cáo khoa học: R120G aB-crystallin promotes the unfolding of reduced a-lactalbumin and is inherently unstable ppt
... the resonance decay (i.e. loss of intensity) of reduced a-lactalbumin in the absence of aB-crystallin arises from aggregation of the molten globule state of this protein. In the presence of aB-crystallin, ... involving R120G aB-crystallin and desmin, and these were proposed to be a result of either the decreased ability of R120G aB-crystallin to ch...
Ngày tải lên: 16/03/2014, 18:20
Báo cáo khoa học: "Extending Lambek grammars: a logical account of minimalist grammars" pot
... minimalist program and the logical view of categorial grammar. We thus obtained a de- scription of minimalist grammars which is quite formal and allows for a better interface with se- mantics, and ... instead of a also applies here. 4 The interface between syntax and semantics In categorial grammar (Moortgat, 1996), the pro- duction of logical forms is essentially based...
Ngày tải lên: 17/03/2014, 07:20
Báo cáo khoa học: Ca2+ rise within a narrow window of concentration prevents functional injury of mitochondria exposed to hypoxia ⁄reoxygenation by increasing antioxidative defence pdf
... permea- bilization of the mitochondrial membrane are involved in mitochondrial damage. Our data demonstrate that hypoxia ⁄ reoxygenation and extramitochondrial Ca 2+ cause functional damage of isolated rat liver ... From these data we conclude that extramitochondrial Ca 2+ at a narrow concentration window exerts a protective effect upon hypoxia ⁄ reoxygenation by increa...
Ngày tải lên: 30/03/2014, 11:20
Báo cáo khoa học: "Consequences of reducing a full model of variance analysis in tree breeding experiments" pps
... provenances), we obtain the following changes in variance compo- nents: This implies modifications for variance components and total variance as shown in table IV. The true variance ... we obtained the following values for the new variance components in terms of those of the original full model: The total variance and the locality and...
Ngày tải lên: 09/08/2014, 03:24