Báo cáo y học: "B lymphocytopenia in rheumatoid arthritis is associated with the DRB1 shared epitope and increased acute phase response" docx

... rheumatoid factor; SE = HLA DRB1 shared epitope. Available online http:/ /arthritis- research.com/4/4/R1 Research article B lymphocytopenia in rheumatoid arthritis is associated with the DRB1 shared ... lymphocytes is plotted on the x axis, and the number of patients in each frequency range is plotted on the y axis. The overlays represent the Ga...

Ngày tải lên: 09/08/2014, 03:24

... sites, including the pubic symphysis and synovial joints. These findings also suggest that in fibrocartilaginous tissues, including the TMJ disc and possibly the pubic symphysis, relaxin decreases collagen ... tem- poromandibular joint (TMJ) disc, and the pubic symphysis. Within the pubic symphysis of several species, the repro- ductive hormone relaxin induces matrix remod...

Ngày tải lên: 09/08/2014, 06:22

... Z would be s terically hindered b y interaction of one of the N-methyl groups at N 1 (that in cis orientation to N 2 )with the pyranose ring of legionaminic acid. The N-methyl signal in 3 gave strong ... accompanying paper [26]. Being hydrophobic and having a signi®cant electronic effect, the N-methyl groups may a djust the appropriate hydro- phobicity and the appropri...

Ngày tải lên: 08/03/2014, 10:20

... Arthritis with Concomitant Therapy Study Group: Infliximab and methotrexate in the treatment of rheumatoid arthritis. Anti-tumor necrosis factor trial in rheumatoid arthritis with concomitant therapy ... protein levelsChanges in disease activity in 30 patients with rheumatoid arthritis at different times during 78 weeks of infliximab therapy as determined by...

Ngày tải lên: 09/08/2014, 01:23

... online http:/ /arthritis- research.com/content/6/6/R535 R535 Vol 6 No 6 Research article Infliximab therapy in rheumatoid arthritis and ankylosing spondylitis-induced specific antinuclear and ... Weisman M, Emery P, Feldmann M, et al.: Infliximab and methotrexate in the treatment of rheumatoid arthritis. Anti-Tumor Necrosis Factor Trial in Rheumatoid Arthritis with...

Ngày tải lên: 09/08/2014, 01:24

... the synovial lining layer and organize into lymphocyte aggregates with germinal centres (GCs) [19–21]. These ectopic lymphoid struc- tures share many features with secondary lymphoid tissue and ... chemokines have an induc- tive function in establishing these microstructures. The induction of BCA-1 and other lymphoid-tissue-inducing chemokines may convert the synovial lesion...

Ngày tải lên: 09/08/2014, 03:24

... patients (discussed above). It is tempting to speculate that chronic production of cytokines, including TNF-α, may affect the myocardium in RA in either an endocrine (originating in the synovium) ... therapy-induced hyperhomocysteinemia to CHF risk in RA has yet to be completely elucidated. Inflammatory cytokines In patients with overt CHF, levels of inflammatory cytokines (...

Ngày tải lên: 09/08/2014, 07:20

... damage in patients with rheumatoid arthritis in clinical remission. Arthritis Rheum 2004, 50:36-42. 36. Kirwan JR: The relationship between synovitis and erosions in rheumatoid arthritis. Br ... Weisman M, Emery P, Feldmann M, et al.: Infliximab and methotrexate in the treatment of rheumatoid arthritis. Anti-Tumor Necrosis Factor Trial in Rheumatoid Arthriti...

Ngày tải lên: 09/08/2014, 08:22

... The acetylation of histones is catalyzed by the histone acetyl- transferases (HATs), which modify lysine residues at the N-terminus of the histones [15]. Such hyperacetylation is associated with the ... multiple sclerosis [17] and systemic lupus erythematodes [18]. In systemic sclerosis (SSc), the knockdown of HDAC7 in skin fibroblasts [19] and the treatment of b...

Ngày tải lên: 09/08/2014, 13:21

... out in the PubMed data- base, using the following keywords: (rheumatoid arthritis OR ankylosing spondylitis OR spondylarthritis) AND (aspergilloma OR fungus ball OR aspergillosis OR sinusitis). ... fungal sinusitis may spread intracranially and, on the other hand, indolent inva- sive aspergillosis may be well tolerated. Evaluating the risk of progression to invasive disease i...

Ngày tải lên: 09/08/2014, 14:22