Báo cáo y học: "Proteinase-3 as the major autoantigen of c-ANCA is strongly expressed in lung tissue of patients with Wegener’s granulomatosis" pptx

... epiphenomenon [10]. One of the unresolved issues is the inability to explain the nonrandom, selected organ injury that defines the WG vasculitis and the concurrent, seemingly random, nature of injury within ‘targeted’ ... the PR-3 expression in normal lung and lung tissue of WG patients, as the lung is the most frequent organ involved in WG [15]. In...

Ngày tải lên: 09/08/2014, 03:24

... during priming in situ; that is, in the secondary lymphoid organs. When anti-CD134 liposomes were injected s.c. in the hind paws, the majority of the CD4 + CD134 + T cells in the joint-draining ... participated in the design of the study and in its coordination. LE participated in the experiments, statistical analysis and interpretation of the results....

Ngày tải lên: 09/08/2014, 06:22

... than the promoter containing only intron 1. Further investigation is needed to elucidate the mechanisms involving the intron regions. We recently developed a recombinant VZV vaccine strain containing ... containing the mumps virus HN gene. In this study, we examined whether the HHV-6 MIEp contain- ing intron 1 functioned as a heterologous expression promoter in the VZV vac...

Ngày tải lên: 11/08/2014, 21:21

... 1A). In the classical view of plant photosynthesis, one part of the photosynthetic electron transfer chain (photosystem II) is segregated into the grana, whilst other components of the system ... loops of core polypeptide CP47 [15]. A further domain (V) underlying and contributing to domains II and I was assigned to the lumenal portion of CP43. In the X-ray structu...

Ngày tải lên: 17/03/2014, 17:20

... tryptase contained in mast cell granules and Smad3 protein in lung tissues using double staining. As shown in Figure 7A, lung tissues in OVA/S mice enhanced the co-localization (yellow color) of ... of mast cell tryptase and Smad3 protein in lung tissues In order t o investigate whether smoke-induced expres- sion of Smad proteins was occurring in mast cells, we e...

Ngày tải lên: 12/08/2014, 13:22

... because they are not hydrolysed by β-glucosidases in the intestine and can be adminis- tered orally [27]. Therefore, the aim of the present study was to evaluate the inhibitory effect of some ... [16]. It in- hibits the activity of SGLT in the kidney leading to glycosuria [17]. Its clinical application; however, is restricted due to hydrolysis by β-glucosidases...

Ngày tải lên: 26/10/2012, 10:04

... SNPs [20]. On the basis of the hypothesis that disease alleles reflect the allelic spectrum of diseases in the general population, the risk of common diseases will be attributable in part to allelic ... population, but increase the disease risk by only 10 to 20% (corresponding to an odds ratio (OR) of 1.10 to 1.20 per copy of the risk allele). (e OR is a me...

Ngày tải lên: 09/08/2014, 20:21

... very difficult especially when this key mus- cle is fibrosed and merges with the surrounding neuroma. The muscle is then indirectly identified as the tissue lying behind the phrenic nerve. The ... were monitored by the neuroanesthetist as the stimulating cur- rent was gradually increased. Simultaneously, the pres- ence of diaphragmatic contraction was judged by...

Ngày tải lên: 10/08/2014, 10:20

... new cases annually and around 66 000 deaths. Globally the incidence of the disease continues to rise, particularly in Caucasian populations [1]. As there is no effective treatment for the disease, ... useful screening tool for health care professionals involved in skin care. On this basis, dermoscopy is poten- tially a new extension to the scope of practice in Podiatry...

Ngày tải lên: 10/08/2014, 21:23

... effect )as well as on the physician's level of uncertainty (the partner effect) while controlling for the influence of the essential elements of SDM assessed on the part of the physician (Figure 1). In ... elements of SDM assessed on the part of the patient; and the influence of the essential elements of SDM assessed on the patient part on the...

Ngày tải lên: 11/08/2014, 05:21