Báo cáo y học: "Differential binding of chemokines to macrop

Báo cáo y học: "Differential binding of chemokines to macrophages and neutrophils in the human inflamed synovium" pps

... for the CXCL8 binding. The chemokine binding sites described on phagocytes may be involved in the migration of these cells into the inflamed joint. Keywords: chemokines, inflamed, receptors, synovium Received: ... thickening of the lining layer (or intima) and infiltration of the sublining layer, mainly by macrophages and lymphocytes [1]. In addition, the...

Ngày tải lên : 09/08/2014, 03:24

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Báo cáo y học: "Differential expression of RANK, RANK-L, and osteoprotegerin by synovial fluid neutrophils from patients with rheumatoid arthritis and by healthy human blood neutrophils" doc

... border and the combined expression of α v β 3 integrin and of certain enzymes (carbonic anhydrase II, vacuolar ATPase, cathepsin). This lends support to the hypothesis that neutrophils could be involved ... are activated during their margination and diapedesis across blood vessels and by cytokines at the site of inflammation [1]. They are involved in various chronic...

Ngày tải lên : 09/08/2014, 10:20

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Báo cáo Y học: Calcium-binding by p26olf, an S100-like protein in the frog olfactory epithelium pot

... constants of the ﬁrst to fourth binding of Ca 21 by assuming the presence of four steps of sequential and ordered binding. To identify the site of the EF-hand corresponding to the nth binding of Ca 21 , ... 90% of the change in the a helix content was attained by binding of two Ca 21 . Interestingly, in the mutants which have only three Ca 21...

Ngày tải lên : 24/03/2014, 04:21

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Báo cáo y học: "Diurnal secretion of growth hormone, cortisol, and dehydroepiandrosterone in pre- and perimenopausal women with active rheumatoid arthritis: a pilot case-control study" ppt

... patients. Whether these combined somatotropic and adrenocortical abnormalities in a proinflammatory cytokine milieu exacerbate the inflammatory process and play a role in the pathogenesis of rheumatoid ... factor-1 (IGF-I), is one of the key pathophysiological mechanisms contributing to the cachexia of normal aging [5]. In a mouse model, overexpression of the inf...

Ngày tải lên : 09/08/2014, 10:20

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Báo cáo y học: "An exploration of how clinician attitudes and beliefs influence the implementation of lifestyle risk factor management in primary healthcare: a grounded theory study" pot

... role, the more they were willing to invest time in addressing them. These views tended to reflect the model of service delivery adopted by the team/service in which they worked and clinicians' ... purposes) with the majority of their clients took a broader view of the relevance of lifestyle risk factors to their role and/ or asking about lifestyle issues wa...

Ngày tải lên : 11/08/2014, 05:21

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Báo cáo y học: "Using theories of behaviour to understand transfusion prescribing in three clinical contexts in two countries: Development work for an implementation trial" pps

... strategy, implementation intention [34]. These theories have been examined thoroughly in other health care settings, they include explanatory factors that are amenable to change, and they include non-volitional ... covering letter, which will explain the purpose and nature of the study, will be included with the initial copy of the questionnaire. The letter will explain...

Ngày tải lên : 11/08/2014, 05:21

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Báo cáo y học: "DAS28: a useful instrument to monitor infliximab treatment in patients with rheumatoid arthritis" pps

... activity to study the validity of the Disease Activity Score and the DAS28. In a study performed in Italy in the late 1990s, it was found that the Disease Activity Score was the best measure to discriminate ... not use the DAS28 to ‘diagnose’ physician opinion on whether or not to increase the infliximab dose. However, the results of Vander Cruyssen and...

Ngày tải lên : 09/08/2014, 07:20

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Báo cáo y học: " Detecting sequence polymorphisms associated with meiotic recombination hotspots in the human genome" pptx

... since the 13-mer motif occurs in only about 40% of human hotspots [32] and the variation in the zinc finger array of the Prdm9 gene can expl ain only about 18% of variation in human recombination ... by LDhat) than the ‘ cold’ C allele. The small recombination rate of the C allele is unlik ely to be due totheartifactofasmallsamplesizebecauseinthe CHB + JP...

Ngày tải lên : 09/08/2014, 22:23

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Báo cáo y học: " Differential binding and co-binding pattern of FOXA1 and FOXA3 and their relation to H3K4me3 in HepG2 cells revealed by ChIP-seq" docx

... proximity and, as indicated by the Co-IP data, some of these factors may even interact at the site of binding. Correlation of FOXA binding and H3K4me3 FOXA TFs are known to be involved in opening of ... binding sites might affect the binding and regulatory activity of the interacting TF [33]. We did not find any evidence of protein-protein interaction betw...

Ngày tải lên : 09/08/2014, 20:21

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Tài liệu Báo cáo Y học: Differential response of neuronal cells to a fusion protein of ciliary neurotrophic factor/soluble CNTF-receptor and leukemia inhibitory factor pot

... for these cytokines are refractory to stimulation. An unusual feature of the IL-6 cytokine family is that the soluble forms of the ligand binding receptor subunits generated by one cell type in ... cDNA level, the C-terminus of the extracellular domain of human CNTF-R (amino acids 1–346) was linked via a single glycine residue to the N-terminus of human CNTF...

Ngày tải lên : 22/02/2014, 07:20

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