Báo cáo y học: "Glucocorticoids: do we know how they work" pot
Báo cáo khoa học: "What do we know about medication errors made via a CPOE system versus those made via handwritten orders"
... we understand by ‘medication errors’, what we mean by ‘computerized physician order entry (CPOE) systems’, how we measure errors, and what types of errors we are ‘reducing’ with CPOE systems. As the ... medication errors (potential and actual errors), the CPOE system was associated with fewer errors, a finding they repeatedly stress. When they examined major medication errors, h...
Ngày tải lên: 25/10/2012, 10:39
Báo cáo sinh học : "What do we know about influenza and what can we do about it" ppsx
... poorly so that they do not cause disease. Live- attenuated influenza virus vaccines were long in use in the former Russian Federation, but their broader availa- bility is comparatively recent. Any vaccine ... Question and Answer QQ&&AA:: WWhhaatt ddoo wwee kknnooww aabboouutt iinnfflluueennzzaa aanndd wwhhaatt ccaann wwee ddoo aabboouutt iitt?? Peter C Doherty* ,† and Stephen J Tu...
Ngày tải lên: 06/08/2014, 19:20
Báo cáo y học: "Thioglycosides as inhibitors of hSGLT1 and hSGLT2: Potential therapeutic agents for the control of hyperglycemia in diabetes"
... chemical synthesized [13, 14]. The most commonly used is known as T-1095 (3-(benzofuran-5-yl)-2',6'-dihydroxy-4'-methylpropio- phenone 2'-O-(6-O-methoxycarbonyl-β-D-glyco- pyranoside) ... energy transfer (FRET) analysis cells were seeded in flat-bottom, poly-D-lysine black-wall, clear bottom, 96-well plates (Becton Dickinson; Heidelberg, Ger- many). Thioglycosides...
Ngày tải lên: 26/10/2012, 10:04
Báo cáo Y học: Rodent a-chymases are elastase-like proteases pot
... purified enzymes were enzymatically active (Fig. 2). Analysis of substrate specificity Because of the high amino acid sequence homology with other a-chymases, such as human and dog chymases, we assumed ... but they displayed no chymase, trypsin, or other kinds of protease activity. The enzymes showed a preference for the P1 site of the following substrates in the order: Val > Ile > Al...
Ngày tải lên: 08/03/2014, 09:20
Báo cáo Y học: Role of critical charged residues in reduction potential modulation of ferredoxin-NADP+ reductase Differential stabilization of FAD redox forms doc
... stabilized by the wild-type enzyme ([SQ] ¼ 22.4% as determined by photoreduction experiments) are known. Thus, by simultaneously solving this Nernst derived two-equation system, the reduction potentials ... of the three FMN redox forms by tyrosine 94 and tryptophan 57 in flavodoxin from Anabaena and its influence on the reduction potentials. Biochemistry 36, 14334– 14344. 22. Pueyo, J.J., Go ´...
Ngày tải lên: 08/03/2014, 23:20
Báo cáo Y học: Molecular mechanisms underlying SHP-1 gene expression potx
... that contained USF1 and USF2, we observed other shifted bands (X and Y) . As bands X and Y were only partially inhibited by 500-fold excess of unlabelled wild-type oligo- nucleotide, we propose that the ... src-homology 2 domains. Src- homology 2 domains interact with phospho-tyrosine resi- dues in many growth factor receptors and thus play an important role in directing the effects of...
Ngày tải lên: 08/03/2014, 23:20
Báo cáo Y học: Domain V of m-calpain shows the potential to form an oblique-orientated a-helix, which may modulate the enzyme’s activity via interactions with anionic lipid potx
... phos- pholipids dimyristoylphosphatidylcholine (Myr 2 PtdCho), dimyristoylphosphatidylethanolamine (Myr 2 PtdEtn) and dimyristoylphosphatidylserine (Myr 2 PtdSer) and all sol- vents, which were of spectroscopic ... haemolytic analysis showed that the peptide is able to lyse erythrocyte membranes (Fig. 4), and monolayer studies showed that it is able to penetrate lipid monolayers mimetic of na...
Ngày tải lên: 17/03/2014, 10:20
Báo cáo Y học: Regulation of mammalian translation factors by nutrients pot
... stimuli increase the phosphorylation of S6Ks and 4E-BP1. However, it is not clear (??) whether they do so by modulating the activity/function of mTOR, or whether they provide separate inputs that ... Phosphory- lation of eEF2 at Thr56 inhibits its activity by preventing it from binding to the ribosome. Phosphorylation of eEF2 is catalysed by eEF2 kinase, an unusual and highly specific en...
Ngày tải lên: 23/03/2014, 21:20
Báo cáo y học: "Local Nasal Specific Immunotherapy for Allergic Rhinitis" potx
... Canonica 121 In healthy volunteers, the allergen sprayed into the nose is slowly transported by mucociliary clear- ance towards the pharynx (Figure 4) and is pro- gressively swallowed, but a fraction ... immunotherapy to Parietaria: long term follow up of a double blind study. Clin Exp Allergy 1997;27:904–8. 36. Andri L, Falagiani P. Symptomatic relief after grass nasal immunotherapy: lastin...
Ngày tải lên: 08/08/2014, 21:20
Báo cáo y học: "Patch Testing in Non-Immediate Drug Eruptions" potx
... pseudolym- phoma and drug hypersensitivity syndrome (drug rash with eosinophilia and systemic symptoms-DRESS). Semin Cutan Med Surg 1996;15:250–7. 3. Pichler WJ. Delayed drug hypersensitivity reactions. ... Delayed drug hypersensitivity reactions— new concepts. Clin Exp Allergy 2007;37:989–99. 5. Romano A, Torres MJ, Quaratino D, et al. Diagnostic evaluations of delayed hypersensitivity to sy...
Ngày tải lên: 08/08/2014, 21:20