... Takeuchi M, Ogasawara S, Maruyama Y, NakajimaT, Takaoka Y et al. (2002) Production in yeast of alpha-galactosidase A, a lysosomal enzyme applicable toenzyme replacement therapy for Fabry disease. Glyco-biology ... B) Heart – endothelial staining in Fabrymouse; (C, D) lung – epithelial cell stainingincreased in Fabry mouse; (E, F) brain micro-vascular endothelial staining in Fabry mouse.Magnification ... Schinkel AH, Wagenaar E, Mol CA & van Deemter L(1996) P-Glycoprotein in the blood–brain barrier of mice in uences the brain penetration and pharmacologi-cal activity of many drugs. J Clin...