Báo cáo khoa học: "Ultrasound-guided central venous catheterization in cancer patients improves the success rate of cannulation and reduces mechanical complications: A prospective observational study of 1,978 consecutive catheterizations" pps

Tài liệu Báo cáo khoa học: 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5¢-phosphate synthases of fungi and archaea docx

Tài liệu Báo cáo khoa học: 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5¢-phosphate synthases of fungi and archaea docx

... deaminase contains 1 equivalent of Zn 2+ per subunit. Thus, the early part of the riboflavin biosynthetic pathway in plants is similar to that of eubacteria, rather than that in fungi and archaea. ... synthases using NADPH as cosubstrate results in progressive disap- pearance of substrate signals and the appearance of a singlet at 42 p.p.m., reflecting the 1¢ carbo...

Ngày tải lên: 18/02/2014, 18:20

12 550 0
Tài liệu Báo cáo khoa học: DNA modification with cisplatin affects sequence-specific DNA binding of p53 and p73 proteins in a target site-dependent manner pptx

Tài liệu Báo cáo khoa học: DNA modification with cisplatin affects sequence-specific DNA binding of p53 and p73 proteins in a target site-dependent manner pptx

... connected with the facts that modification of particular sites in the genome of living cells is naturally stochastic on the one hand, and in uenced by the actual structural and functional state of the given ... ability of the particular p53 target site to accommodate the cisplatin IACs. The higher the probability of formation of the cisplatin IACs within...

Ngày tải lên: 19/02/2014, 05:20

14 598 0
Báo cáo khoa học: Endogenous tetrahydroisoquinolines associated with Parkinson’s disease mimic the feedback inhibition of tyrosine hydroxylase by catecholamines doc

Báo cáo khoa học: Endogenous tetrahydroisoquinolines associated with Parkinson’s disease mimic the feedback inhibition of tyrosine hydroxylase by catecholamines doc

... l-3,4- dihydroxyphenylalanine (l-DOPA), which is the rate- limiting step in synthesis of the catecholamines DA, norepinephrine and epinephrine. TH consists of four identical subunits that contain a C-terminal catalytic domain ... may provide a negative charge that interacts with the amino group of DA and the pyridine moiety of NMNorsal in opposition to the bide...

Ngày tải lên: 07/03/2014, 05:20

13 487 0
Báo cáo khoa học: A new rice zinc-finger protein binds to the O2S box of the a-amylase gene promoter pptx

Báo cáo khoa học: A new rice zinc-finger protein binds to the O2S box of the a-amylase gene promoter pptx

... hybridization, 4 buttheincreaseinRAMY mRNA level occurs prior to that of the Amy2 mRNA level in the GA-treated aleurone tissues. These data suggest that RAMY may act as a trans-acting protein and is probably involved ... specifically to the O2S elemen t. We have also determined the importance of the amino acids within the binding domain of RAMY protein and analyzed t...

Ngày tải lên: 16/03/2014, 18:20

7 359 0
Báo cáo y học: "Hereditary angioedema: beyond international consensus - circa December 2010 - The Canadian Society of Allergy and Clinical Immunology Dr. David McCourtie Lecture" pps

Báo cáo y học: "Hereditary angioedema: beyond international consensus - circa December 2010 - The Canadian Society of Allergy and Clinical Immunology Dr. David McCourtie Lecture" pps

... with large phase IV clinical trials, meta analyses, data base registry validation of ap proaches including quality of life and cost benefit analyses, safety, and head-to- head clinical trials investigating ... the Diagnosis, Therapy and Management of Hereditary Angioedema is reviewed in light of the newly published phase III Clinical trials for prevention and therapy of...

Ngày tải lên: 08/08/2014, 21:20

14 698 0
Tài liệu Báo cáo khoa học: Transient RNA–protein interactions in RNA folding docx

Tài liệu Báo cáo khoa học: Transient RNA–protein interactions in RNA folding docx

... between peptide and RNA, the overall charge of the peptide was crucial for the activity, as the replacement of sin- gle basic amino acids with alanine resulted in the annealing rate constant decreasing by a ... RNA chaperone also has annealing activity, it can catalyze the strand displacement event in two ways: by destabilizing edges and bulges, and by favoring...

Ngày tải lên: 14/02/2014, 19:20

9 601 1
Tài liệu Báo cáo khoa học: NirF is a periplasmic protein that binds d1 heme as part of its essential role in d1 heme biogenesis pdf

Tài liệu Báo cáo khoa học: NirF is a periplasmic protein that binds d1 heme as part of its essential role in d1 heme biogenesis pdf

... similar to that in Asp141 of Met8P. The idea of NirF being a dehydrogenase is appealing because of the presence of a putative nucleotide-bind- ing motif in the N-terminal of the protein sequence and ... Andreas Schlueter and Alfred Phu ¨ ler at the University of Biele- feld are thanked for their kind gift of plasmid pMS255. Dr Katalin di Gleria at The Wea...

Ngày tải lên: 15/02/2014, 01:20

12 614 0
Tài liệu Báo cáo khoa học: Epidermal growth factor receptor in relation to tumor development: EGFR gene and cancer ppt

Tài liệu Báo cáo khoa học: Epidermal growth factor receptor in relation to tumor development: EGFR gene and cancer ppt

... 7p12-13 and codes for a 170kDa receptor tyrosine kinase. All ERBB proteins have four functional domains: an extracellular ligand-binding domain; a transmembrane domain; an intracellular tyrosine kinase ... kinase domain; and a C-terminal regulatory domain [2]. The extracellular domain is subdivided further into four domains. The tyrosine kinase domain consists of an N-lobe an...

Ngày tải lên: 16/02/2014, 09:20

8 684 0
Tài liệu Báo cáo khoa học: Epidermal growth factor receptor in relation to tumor development: EGFR-targeted anticancer therapy doc

Tài liệu Báo cáo khoa học: Epidermal growth factor receptor in relation to tumor development: EGFR-targeted anticancer therapy doc

... I, Kobayashi K, Yamazaki K, Asahina H, Inoue A, Hagiwara K, Sunaga N, Yanagitani N, Hida T et al. (2009) Combined Survival Analysis of Prospective Clinical Trials of Gefitinib for Non-Small Cell ... non–small cell lung cancer Imatinib was designed to compete with ATP at the ATP-binding site within the tyrosine kinase domain of ABL, which is activated as a result of the chr...

Ngày tải lên: 16/02/2014, 09:20

7 511 0
Tài liệu Báo cáo khoa học: Mixed lineage leukemia: roles in gene expression, hormone signaling and mRNA processing docx

Tài liệu Báo cáo khoa học: Mixed lineage leukemia: roles in gene expression, hormone signaling and mRNA processing docx

... transactivation domain. The DNA-bind- ing domain is responsible for DNA binding specificity and dimerization, and the ligand-binding domain is responsible for binding of the ligand and associated induced ... of hormone-respon- sive genes in a hormone-dependent manner [63]. Most NRs share a common structural organization that includes a DNA-binding domain, a ligand-bin...

Ngày tải lên: 16/02/2014, 14:20

15 607 0
w