Báo cáo khoa học: "Clinical implications of novel activating EGFR mutations in malignant peritoneal mesothelioma" ppt

... seven novel and one known point mutations in the EGFR- TK domain in MPM patients. All mutations are clustered and reside near the ATP- binding cleft of the tyrosine kinase domain. Presence of each ... cohort of MPM samples (n = 29) by DHPLC and sequencing analysis, and ide ntified eight mutations in the tyrosine kinase domain ( TKD) of EGFR. Of the 8 mutations in...

Ngày tải lên: 09/08/2014, 03:22

... prostheses in 6 (6.3%) of 95 patients[2]. In 2001, Mittenmayer et al. reported major complications in 19 of 100 patients using uncemented tumor prostheses, consisting of 11 patients showing aseptic ... pain in the left thigh during walking. Due to gradual aggravation of the pain, she visited our depart- ment on September 6, 2007. X-ray examination revealed fracture at the base...

Ngày tải lên: 09/08/2014, 04:21

... in its contouring will result in a large change in DSC. In terms of the prostate bed our findings are not surprising given that AABS algorithms are typically developed to detect and segment intact ... P, Portnoy O, Pfeffer MR: An interobserver study of prostatic fossa clinical target volume delineation in clinical practice: are regions of recurrence adequately targeted? Am J C...

Ngày tải lên: 09/08/2014, 09:21

... similar blue shift of fluorescence peak of thiol-capped CdTe QDs within less than 10 min of QD uptaking in living cells caused by surface photooxida- tion [16]. The reported blue shift in CdTe QDs is ... Yun.Chen@wlab.gu.se 1 Department of Theoretical Chemistry, School of Biotechnology, Royal Institute of Technology, S-106 91 Stockholm, Sweden 2 Department of Molecular and C...

Ngày tải lên: 11/08/2014, 00:22

... This indicates that the binding of echinenone to the com- plex is rather specific. Results obtained with the CrtO-less strain suggest that the carotenoid binding site in the cyt b 6 f complex of ... and 280 nm of echinenone in the cyt b 6 f complex isolated from strains retaining CrtO, this carotene appears to be in the all-trans form. A characteristic difference in the carotenoi...

Ngày tải lên: 07/03/2014, 16:20

... legionaminic acid modifications found on the flagellin of 11168 are involved in the ability of this strain to persist in the gastrointestinal tract of chickens (S. L. Howard, A. Jagannathan, E. C. ... coloniza- tion of host cells. Recently, the use of metabolomics permitted the unequiv- ocal characterization of unique flagellin modifications in Campylobacter, including novel l...

Ngày tải lên: 23/03/2014, 06:20

... minimum (MIN) of the curve of joint movement. Beside this, the mean values of MAX and MIN were considered. For ankle joint, in addition to ROM on sagittal plane, peak of plantarflexion, peak of ... forward dis- placement of the center of gravity creating instability dur- ing standing and walking. The self-selected walking speed of obese subjects is 1.17 ± 0.10 m/sec; Brownin...

Ngày tải lên: 19/06/2014, 10:20

... antimicrobial agents featuring a fluorine atom in position 6 and a piperazinyl or pyrrolidinyl substituent in position 7 of the quinoline nucleus [24]. Norfloxacin-gly- cine acetate (NFLXGA), a ... Pharmacokinetic studies of norfloxacin in laboratory animals. Chemotherapy 1984, 30, 288-296. 8. Gips M, Soback S. Norfloxacin pharmacokinetics in lactat- ing cows with sub-clinical...

Ngày tải lên: 07/08/2014, 20:23

... prognosis of the patient unlike that of CRP. Interleukin-6 (IL-6) is a multi-poietic cytokine that induces the growth and differentiation of immune cells, the production and expression of other cytokines, ... rendered by Dr.Ravindra Bhat and Dr. Rajasabapathy of Ganga hospital, Coimbatore in helping us bring out this paper. Conflict of interest The authors declare that they have...

Ngày tải lên: 09/08/2014, 01:24

... prior Duration of CB (DoCB) is the duration of therapy in months only in patients who have derived CB and including patient still on treatment. Duration of treat- ment (DoT) is the duration of therapy in ... withdrawal of tamoxifen therapy at devel- opment of resistance to tamoxifen. Our case-series and previously reported case series confirm this finding in clinical setti...

Ngày tải lên: 09/08/2014, 02:21