Báo cáo khoa học: "Clinical implications of novel activating EGFR mutations in malignant peritoneal mesothelioma" ppt

... seven novel and one known point mutations in the EGFR- TK domain in MPM patients.All mutations are clustered and reside near the ATP-binding cleft of the tyrosine kinase domain. Presence of each ... cohort of MPM samples (n = 29) byDHPLC and sequencing analysis, and ide ntified eight mutations in the tyrosine kinase domain ( TKD) of EGFR. Of the 8 mutations in the TK domain, 7 were novel ... 8:88http://www.wjso.com/content/8/1/88Page 2 of 10RESEA R C H Open AccessClinical implications of novel activating EGFR mutations in malignant peritoneal mesotheliomaJason M Foster1,4*, Uppala Radhakrishna1, Venkatesh Govindarajan1,...

Báo cáo khoa học: "Clinical experience of novel interconnected porous hydroxyapatite ceramics for the revision of tumor prosthesis: a case report" pdf

... prostheses in 6 (6.3%) of 95 patients[2]. In 2001, Mittenmayer et al. reported major complications in 19 of 100 patients using uncemented tumor prostheses,consisting of 11 patients showing aseptic ... pain in the left thigh during walking. Due togradual aggravation of the pain, she visited our depart-ment on September 6, 2007. X-ray examination revealedfracture at the base of the stem of ... osteosclerosis in 61% of the patients after 6 months. Concerning caution-ary items at the time of filling during the operation,Nakase et al. described that the initial strength acquired islower using...

Báo cáo khoa học: "Technology Assessment of Automated Atlas Based Segmentation in Prostate Bed Contouring" pptx

... in its contouring willresult in a large change in DSC. In terms of the prostatebed our findings are not surprising given that AABSalgorithms are typically developed to detect and segmentintact ... P,Portnoy O, Pfeffer MR: An interobserver study of prostatic fossa clinicaltarget volume delineation in clinical practice: are regions of recurrenceadequately targeted? Am J Clin Oncol 2011, 34(2):145-149.14. ... levels of inter- and intra-observer variabil-ity in target volume delineation (TVD) has been repeat-edly demonstrated in prostate cancer radi otherapy [4-7]. In fact, it has been argued that inter-observer...

báo cáo khoa học: "Optical characterization of colloidal CdSe quantum dots in endothelial progenitor cells" pptx

... similar blue shift of fluorescencepeak of thiol-capped CdTe QDs within less than 10 min of QD uptaking in living cells caused by surface photooxida-tion [16]. The reported blue shift in CdTe QDs is ... Yun.Chen@wlab.gu.se1Department of Theoretical Chemistry, School of Biotechnology, RoyalInstitute of Technology, S-106 91 Stockholm, Sweden2Department of Molecular and Clinical Medicine/Clinical Physiology,Wallenberg ... description in Ref. [10]and references therein), which were octadecylaminecoated so that they were not water soluble. They weredissolved in chloroform and a same volume of a watersolution containing...

Báo cáo khoa học: Functional implications of pigments bound to a cyanobacterial cytochrome b6f complex potx

... Thisindicates that the binding of echinenone to the com-plex is rather speciﬁc.Results obtained with the CrtO-less strain suggestthat the carotenoid binding site in the cyt b6f complex of ... and280 nm of echinenone in the cyt b6f complex isolatedfrom strains retaining CrtO, this carotene appears tobe in the all-trans form.A characteristic difference in the carotenoid content of the ... reduction of cyt b6by dithionite. Dotted line, difference spectrum of the solid and dashedlines. (B) Kinetics of the reoxidation of cytochrome b6by air and of the absorbance shift of chlorophyll...

Báo cáo khoa học: Identiﬁcation of novel carbohydrate modiﬁcations on Campylobacter jejuni 11168 ﬂagellin using metabolomics-based approaches docx

... legionaminic acid modiﬁcationsfound on the ﬂagellin of 11168 are involved in theability of this strain to persist in the gastrointestinaltract of chickens (S. L. Howard, A. Jagannathan,E. C. ... coloniza-tion of host cells. Recently, the use of metabolomics permitted the unequiv-ocal characterization of unique ﬂagellin modiﬁcations in Campylobacter,including novel legionaminic acid sugars in ... ﬂagellin using metabolomics-basedapproaches. Detected as their corresponding CMP-linked precursors, struc-tural information on the ﬂagellin modiﬁcations was obtained using a com-bination of MS...

báo cáo hóa học: " Clinical implications of gait analysis in the rehabilitation of adult patients with "Prader-Willi" Syndrome: a cross-sectional comparative study ("Prader-Willi" Syndrome vs matched obese patients and healthy subjects)" docx

... minimum (MIN) of the curve of joint movement. Beside this, the mean values of MAX and MIN were considered. For ankle joint, in addition to ROM on sagittal plane, peak of plantarflexion,peak of ... forward dis-placement of the center of gravity creating instability dur-ing standing and walking.The self-selected walking speed of obese subjects is 1.17 ±0.10 m/sec; Browning et al [21] reported ... CentralPage 1 of 7(page number not for citation purposes)Journal of NeuroEngineering and RehabilitationOpen AccessResearchClinical implications of gait analysis in the rehabilitation of adult...

Báo cáo khoa học: "Clinical pharmacokinetics of norfloxacin-glycine acetate after intravenous and oral administration in pigs" doc

... antimicrobial agents featuring a fluorine atom in position 6 and a piperazinyl or pyrrolidinyl substituent in position 7 of the quinoline nucleus [24]. Norfloxacin-gly-cine acetate (NFLXGA), a ... Pharmacokinetic studies of norfloxacin in laboratory animals. Chemotherapy 1984, 30, 288-296. 8. Gips M, Soback S. Norfloxacin pharmacokinetics in lactat-ing cows with sub-clinical and clinical ... Pharmacokinetics of norfloxacin in pigs 355Tabl e 1 . Parmacokinetic parameters that describe the disposition of norfloxacin-glycine acetate (7.2 mg/kg body weight) after in- travenous and oral administration...

báo cáo khoa học: "Clinical significance of preoperative serum interleukin-6 and C-reactive protein level in breast cancer patients" pot

... prognosis of the patientunlike that of CRP.Interleukin-6 (IL-6) is a multi-poietic cytokine thatinduces the growth and differentiation of immune cells,the production and expression of other cytokines, ... rendered by Dr.Ravindra Bhat and Dr.Rajasabapathy of Ganga hospital, Coimbatore in helping us bring out thispaper.Conflict of interestThe authors declare that they have no competing interests.Author ... staging. Relevant investigations were made to find out the presence of distant metastasis.Statistical analysis of the data was then processed.Results: Increases in cancer invasion and staging...

báo cáo khoa học: "Clinical relevance of "withdrawal therapy" as a form of hormonal manipulation for breast cancer" doc

... priorDuration of CB (DoCB) is the duration of therapy in months only in patients who have derived CB andincluding patient still on treatment. Duration of treat-ment (DoT) is the duration of therapy in ... withdrawal of tamoxifen therapy at devel-opment of resistance to tamoxifen. Our case-series andpreviously reported case series confirm this finding in clinical setting.The lack of response in the ... response in the remaining patients onwithdrawal of tamoxifen could partly be explained b ythe growth promoting action of natural estrogen in thebody as seen in the abov e in- vivo study [12]....

Xem thêm