Báo cáo khoa học: "Intraabdominal and retroperitoneal soft-tissue sarcomas - outcome of surgical treatment in primary and recurrent tumors" potx

Báo cáo khoa học: Amino acid limitation regulates the expression of genes involved in several speciﬁc biological processes through GCN2-dependent and GCN2-independent pathways ppt

... devoid of a given essential amino acid. Our data suggest that the GCN2 pathway is directly involved in the regulation of amino acid and proteinmetabolism, as many of the genes involved in these processes ... Amino acid limitation regulates the expression of genes involved in several speciﬁc biological processes through GCN2-dependent and GCN2-independent pathways Christiane Deval, ... regulated by amino acid star-vation.Further investigations are necessary to determine the relevance of the amino acid regulation of the genes involved in carbohydrate and lipid metabolism. In par-ticular,...

Báo cáo khoa học: Alpha-fetoprotein antagonizes X-linked inhibitor of apoptosis protein anticaspase activity and disrupts XIAP–caspase interaction ppt

... AFP antagonizes XIAP functionFEBS Journal 273 (2006) 38373849 ê 2006 The Authors Journal compilation ê 2006 FEBS 3845 Alpha-fetoprotein antagonizes X-linked inhibitor of apoptosis protein anticaspase ... Ac-Asp-Glu-Val-Asp-7-amino-4-methyl coumarin; AFP, a-fetoprotein; IAP, inhibitor of apoptosis protein; IBM, IAP-bindingmotif; RFU, relative ﬂuorescence units; XIAP, X-linked inhibitor of apoptosis protein. FEBS Journal 273 ... cellular inhibitor- of- apoptosis proteins (IAPs), bind directly to active caspases and actas natural inhibitors of caspase activity [7]. The IAPfamily, currently identiﬁed in humans consists of X-linked...

Báo cáo khoa học: Val216 decides the substrate speciﬁcity of a-glucosidase in Saccharomyces cerevisiae doc

... maltose cannotbind to the active site because the side chain of Val216 interfere with binding of a 4-linked glucose. The CG1 of Val216 is too close to the O3Â of maltose. On the otherhand, both ... but neither the Gly217 nor the Ser218 mutant changed their substrate speciﬁcity, indicating that Val216 is an important residuediscriminating the a-1,4- and 1,6-glucosidic linkages of substrates.Keywords: ... wereused as substrates, the enzyme activity was determined as the rate of hydrolysis of the substrate by measuring the release of glucose according to the enzymatic method of NADP+reduction using hexokinase...

... Hierarchy in a modiﬁed hidden Markov modelLin-Yi ChouUniversity of WaikatoHamiltonNew Zealandlc55@cs.waikato.ac.nzAbstractThis paper explores techniques to take ad-vantage of the fundamental ... 6: The graph of micro-average F -measureagainst the number of training sentences duringtext chunking (A: MHHMM, B: HHMM and C:HMM) The ﬁrst ﬁnding is that the size of training datadramatically ... model takesadvantage of the recurring patterns within the hierarchy, and the clusters that exist in some sequences of observations, in order to increase the extraction accuracy. Thispaper also...

Báo cáo khoa học: DYNLL/LC8: a light chain subunit of the dynein motor complex and beyond pptx

... Fitz-gerald MC & Hendrickson WA (2007) Structural and thermodynamic characterization of a cytoplasmic dynein light chain intermediate chain complex. ProcNatl Acad Sci USA 104, 10028–10033.16 Hall ... and mediatesDNA damage-induced p53 nuclear accumulation.J Biol Chem 280, 8172–8179.11 Navarro C, Puthalakath H, Adams JM, Strasser A &Lehmann R (2004) Egalitarian binds dynein light chain to ... on the dynein motor complex Originally it was suggested that LC8 acts as a cargoadapter that links the cargo to the motor complex. However, DIC and Swallow, a cargo protein, occupy the very same...

Báo cáo khoa học: Effects on protease inhibition by modifying of helicase residues in hepatitis C virus nonstructural protein 3 pot

... (5Â-TCCCGTGTGTGCAGACCATCTTGAAT -3 ), H528A forward primer(5Â-TCCCGTGTGTCAAGACGCTCTTGAAT -3 ) or H 52 8Sforward primer (5Â-TCCCGTGTGTCAAGACTCTCTTGAAT -3 ) and reverse primer (5Â-AGTCCCGGGGTGTTCATGTATGCTC -3 ). ... C, Cai Z, Kim YC, Kumar R, Yuan F, Shi PY,Kao C & Luo G (2005) Stimulation of hepatitis C virus (HCV) nonstructural protein 3 (NS3) helicase activity by the NS3 protease domain and by HCV ... 59795986 ê 2007 The Authors Journal compilation ê 2007 FEBS Effects on protease inhibition by modifying of helicase residues in hepatitis C virus nonstructural protein 3 Goăran Dahl1, Anja Sandstroăm2,...

Báo cáo khoa học: The consensus motif for N-myristoylation of plant proteins in a wheat germ cell-free translation system ppt

... yielding pTA2–AGG1. The coding region for mature AGG1 fused with a DNA fragment encoding the myristoylation motif Met-Gly-Ala-Ala-Ala-Ala-Ala-Ala-Ala-Ala or Met-Gly-Ala-Ala-Ala-Ser-Ala-Ala-Ala-Ala ... Structure of mature AGG1 fused at its N-terminus to the myristoylation motifs Met-Gly-Xaa-Ala-Ala-Ala-Ala-Ala-Ala-Ala (Myr–AGG1-3X 6A) orMet-Gly-Xaa-Ala-Ala-Ser-Ala-Ala-Ala-Ala(Myr–AGG1-3X6S). ... N-terminus to the myristoylationmotifs Met-Gly-Xaa-Ala-Ala-Ala-Ala-Ala-Ala-Ala(Myr–AGG1-3X 6A) or Met-Gly-Xaa-Ala-Ala-Ser-Ala-Ala-Ala-Ala (Myr–AGG1-3X6S), with position 3 of each motif separately occupied...

Báo cáo khoa học: "Learning Noun Phrase Anaphoricity to Improve Coreference Resolution: Issues in Representation and Optimization" ppt

... each of the remaining NPs.Applying the classiﬁer. To determine the anaphoricity of an NP in a test document, aninstance is created for it as during training and pre-sented to the anaphoricity ... Su, and Chew LimTan. 2003. Coreference resolution using competitivelearning approach. In Proceedings of the ACL, pages176–183. Learning Noun Phrase Anaphoricity to Improve Coreference Resolution: Issues ... acquired anaphoricity in- formation into coreference systems, however, haveled to the degradation in resolution performance.This paper examines several key issues in com-puting and using anaphoricity...

Báo cáo khoa học: "Collaborative control initiatives targeting zoonotic agents of alveolar echinococcosis in the northern hemisphere" ppsx

... because of the cost of the drug, the replacement of sled-dogs by machines decreased remarkably the incidence of alveolar echinococcosis in the island. However, with the presence of other definitive ... Taken together, these findings indicate that invasion of young infected foxes into the territories left by the hunted foxes could maintain or increase the preva-lence rate of infection. In Japan, ... mkamiya@rakuno.ac.jpCollaborative control initiatives targeting zoonotic agents of alveolar echinococcosis in the northern hemisphereMasao Kamiya*OIE Reference Laboratory for Echinococcosis and Laboratory of Environmental...

Báo cáo khoa học: "Intraabdominal and retroperitoneal soft-tissue sarcomas - outcome of surgical treatment in primary and recurrent tumors" potx

... RESEARC H Open AccessIntraabdominal and retroperitoneal soft-tissue sarcomas - outcome of surgical treatment in primary and recurrent tumorsAne S Sogaard1, Jacob M Laurberg1, ... thepopulation included in the analysis was 73 primary and 28 recurrent sarcomas for a total of 101 contacts.Sixty-five of 73 (89%) primary sarcomas had surgery, and 22 of 28 (79%) patients with recurrent ... however, peri- and postoperative complications in patients with recurrent disease were not increased, and the 30-day mortality waszero, stressing the im portance and impact of optimalintra- and postoperative...

báo cáo khoa học: " Effective continuing professional development for translating shared decision making in primary care: A study protocol" docx

... tance of addressing decision making in primary care, the sector in which most indivi-duals seek health-related advice [4].The importance of translating shared decision making into primary careGrowing ... Publishers Inc., San Francisco,California; 1994.doi:10.1186/1748-5908-5-83Cite this article as: Légaré et al.: Effective continuing professional development for translating shared decision making in ... 5:83http://www.implementationscience.com/content/5/1/83Page 2 of 6 STUD Y PROT O C O L Open Access Effective continuing professional development for translating shared decision making in primary care: A study...

Báo cáo khoa hoc:" Prospective Epidemiological Observations on the Course of the Disease in Fibromyalgia Patients" doc

... reasons. In conclusion, independent of the applied therapeuticmanagement of the disease, there was neither a clinicalrelevant benefit nor a worsening of symptoms in ourinvestigated group of patients.AcknowledgementWe ... 1 of 6(page number not for citation purposes)Journal of Negative Results in BioMedicineOpen AccessBrief report Prospective Epidemiological Observations on the Course of the Disease in Fibromyalgia ... and the family situation, although the degree of pain experienced remainunchanged. In comparison with the initial examination, there was no change in either work-capacityor disability-pension...

báo cáo khoa học: " A new model for the characterization of infection risk in gunshot injuries:Technology, principal consideration and clinical implementation" pptx

... Lightspeed, USA) at 120 kV and 200 mA.Analysis The data obtained were stored in a digital format(DICOM) and transferred to a personal computer for further analysis. Stat istical analyses were per formedusing ... full metal jacket bullets.Infiltration depth of barium titanate particles in the temporary cavity The radiological examination of the infiltration depth o fbarium titanate particles within the ... temporarycavity.DiscussionThis model for examining potential wound contamina-tion with radio-opaque barium titanate particles is a simple and reproducible method of systematic examina-tion in the field of terminal ballistics....

báo cáo khoa học: " Comparative transcriptional survey between laser-microdissected cells from laminar abscission zone and petiolar cortical tissue during ethylene-promoted abscission in citrus leaves" potx

... AccessResearch article Comparative transcriptional survey between laser-microdissected cells from laminar abscission zone and petiolar cortical tissue during ethylene-promoted abscission in citrus leavesJavier ... between the laminar abscission zone cells and the petiolar cortical cells. Ratio and number of ethylene-regulated ESTs in laminar abscission zone cells (open box) or petiolar cortical cells (filled ... (Fig-Expression of genes encoding protein kinasesFigure 9Expression of genes encoding protein kinases. Expression ratio (log2) between laminar abscission zone cells and petiolar cortical cells (LAZ/Pet)...

Báo cáo khoa học: " Social support during intensive care unit stay might improve mental impairment and consequently health-related quality of life in survivors of severe acute respiratory distress syndrome" pps

... (PTSD) in long-term survivors of acute respiratory distress syndrome (ARDS). We wished to evaluate the influence of PTSD on HRQoL and to investigate the influence of perceived social support during ... support, empathy and helpful accepting behaviour of family caregivers during the life- threatening and traumatic ICU stay. Passive coping strategies, which are related to dimin-ished social support, ... online http://ccforum.com/content/10/5/R147Page 1 of 12(page number not for citation purposes)Vol 10 No 5Research Social support during intensive care unit stay might improve mental impairment...

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