... devoid of a given essential amino acid. Our data suggest that the GCN2 pathway is directly involved in the regulation of amino acid and protein metabolism, as many of the genes involved in these processes ... Amino acid limitation regulates the expression of genes involved in several specific biological processes through GCN2-dep...
Ngày tải lên: 07/03/2014, 03:20
... AFP antagonizes XIAP function FEBS Journal 273 (2006) 38373849 ê 2006 The Authors Journal compilation ê 2006 FEBS 3845 Alpha-fetoprotein antagonizes X-linked inhibitor of apoptosis protein anticaspase ... Ac-Asp-Glu-Val-Asp-7-amino-4-methyl coumarin; AFP, a-fetoprotein; IAP, inhibitor of apoptosis protein; IBM, IAP-binding motif; RFU, relative fluorescence units; XIAP...
Ngày tải lên: 07/03/2014, 12:20
Báo cáo khoa học: Val216 decides the substrate specificity of a-glucosidase in Saccharomyces cerevisiae doc
... maltose cannot bind to the active site because the side chain of Val216 interfere with binding of a 4-linked glucose. The CG1 of Val216 is too close to the O3Â of maltose. On the other hand, both ... but neither the Gly217 nor the Ser218 mutant changed their substrate specificity, indicating that Val216 is an important residue discriminating the a-1,4- and 1,6-...
Ngày tải lên: 07/03/2014, 16:20
Báo cáo khoa học: "Techniques to incorporate the benefits of a Hierarchy in a modified hidden Markov model" pptx
... Hierarchy in a modified hidden Markov model Lin-Yi Chou University of Waikato Hamilton New Zealand lc55@cs.waikato.ac.nz Abstract This paper explores techniques to take ad- vantage of the fundamental ... 6: The graph of micro-average F -measure against the number of training sentences during text chunking (A: MHHMM, B: HHMM and C: HMM) The first finding is that the...
Ngày tải lên: 08/03/2014, 02:21
Báo cáo khoa học: DYNLL/LC8: a light chain subunit of the dynein motor complex and beyond pptx
... Fitz- gerald MC & Hendrickson WA (2007) Structural and thermodynamic characterization of a cytoplasmic dynein light chain intermediate chain complex. Proc Natl Acad Sci USA 104, 10028–10033. 16 Hall ... and mediates DNA damage-induced p53 nuclear accumulation. J Biol Chem 280, 8172–8179. 11 Navarro C, Puthalakath H, Adams JM, Strasser A & Lehmann R (2004) Egalitarian...
Ngày tải lên: 14/03/2014, 22:20
Báo cáo khoa học: Effects on protease inhibition by modifying of helicase residues in hepatitis C virus nonstructural protein 3 pot
... (5Â-TCCCGTGTGT GCAGACCATCTTGAAT -3 ), H528A forward primer (5Â-TCCCGTGTGTCAAGACGCTCTTGAAT -3 ) or H 52 8S forward primer (5Â-TCCCGTGTGTCAAGACTCTCTTG AAT -3 ) and reverse primer (5Â-AGTCCCGGGGTGTT CATGTATGCTC -3 ). ... C, Cai Z, Kim YC, Kumar R, Yuan F, Shi PY, Kao C & Luo G (2005) Stimulation of hepatitis C virus (HCV) nonstructural protein 3 (NS3) helicase activity by...
Ngày tải lên: 16/03/2014, 06:20
Báo cáo khoa học: The consensus motif for N-myristoylation of plant proteins in a wheat germ cell-free translation system ppt
... yielding pTA2–AGG1. The coding region for mature AGG1 fused with a DNA fragment encoding the myristoylation motif Met-Gly-Ala-Ala-Ala-Ala-Ala-Ala- Ala-Ala or Met-Gly-Ala-Ala-Ala-Ser-Ala-Ala-Ala-Ala ... Structure of mature AGG1 fused at its N-terminus to the myristoylation motifs Met-Gly-Xaa-Ala-Ala- Ala-Ala-Ala-Ala-Ala (Myr–AGG1-3X 6A) or Met-Gly-Xaa-Ala-Ala-Ser-Ala-Ala-Ala-Ala...
Ngày tải lên: 29/03/2014, 21:20
Báo cáo khoa học: "Learning Noun Phrase Anaphoricity to Improve Coreference Resolution: Issues in Representation and Optimization" ppt
... each of the remaining NPs. Applying the classifier. To determine the anaphoricity of an NP in a test document, an instance is created for it as during training and pre- sented to the anaphoricity ... Su, and Chew Lim Tan. 2003. Coreference resolution using competitive learning approach. In Proceedings of the ACL, pages 176–183. Learning Noun Phrase Anaphoricity to I...
Ngày tải lên: 31/03/2014, 03:20
Báo cáo khoa học: "Collaborative control initiatives targeting zoonotic agents of alveolar echinococcosis in the northern hemisphere" ppsx
... because of the cost of the drug, the replacement of sled-dogs by machines decreased remarkably the incidence of alveolar echinococcosis in the island. However, with the presence of other definitive ... Taken together, these findings indicate that invasion of young infected foxes into the territories left by the hunted foxes could maintain or increase th...
Ngày tải lên: 07/08/2014, 20:23
Báo cáo khoa học: "Intraabdominal and retroperitoneal soft-tissue sarcomas - outcome of surgical treatment in primary and recurrent tumors" potx
... RESEARC H Open Access Intraabdominal and retroperitoneal soft-tissue sarcomas - outcome of surgical treatment in primary and recurrent tumors Ane S Sogaard 1 , Jacob M Laurberg 1 , ... the population included in the analysis was 73 primary and 28 recurrent sarcomas for a total of 101 contacts. Sixty-five of 73 (89%) primary sarcomas had surgery,...
Ngày tải lên: 09/08/2014, 03:22
báo cáo khoa học: " Effective continuing professional development for translating shared decision making in primary care: A study protocol" docx
... tance of addressing decision making in primary care, the sector in which most indivi- duals seek health-related advice [4]. The importance of translating shared decision making into primary care Growing ... Publishers Inc., San Francisco, California; 1994. doi:10.1186/1748-5908-5-83 Cite this article as: Légaré et al.: Effective continuing professional development...
Ngày tải lên: 10/08/2014, 10:23
Báo cáo khoa hoc:" Prospective Epidemiological Observations on the Course of the Disease in Fibromyalgia Patients" doc
... reasons. In conclusion, independent of the applied therapeutic management of the disease, there was neither a clinical relevant benefit nor a worsening of symptoms in our investigated group of patients. Acknowledgement We ... 1 of 6 (page number not for citation purposes) Journal of Negative Results in BioMedicine Open Access Brief report Prospective Epidemiological...
Ngày tải lên: 11/08/2014, 08:20
báo cáo khoa học: " A new model for the characterization of infection risk in gunshot injuries:Technology, principal consideration and clinical implementation" pptx
... Lightspeed, USA) at 120 kV and 200 mA. Analysis The data obtained were stored in a digital format (DICOM) and transferred to a personal computer for further analysis. Stat istical analyses were per formed using ... full metal jacket bullets. Infiltration depth of barium titanate particles in the temporary cavity The radiological examination of the infiltration depth...
Ngày tải lên: 11/08/2014, 20:21
báo cáo khoa học: " Comparative transcriptional survey between laser-microdissected cells from laminar abscission zone and petiolar cortical tissue during ethylene-promoted abscission in citrus leaves" potx
... Access Research article Comparative transcriptional survey between laser-microdissected cells from laminar abscission zone and petiolar cortical tissue during ethylene-promoted abscission in citrus leaves Javier ... between the laminar abscission zone cells and the petiolar cortical cells. Ratio and number of ethylene-regulated ESTs i...
Ngày tải lên: 12/08/2014, 03:21
Báo cáo khoa học: " Social support during intensive care unit stay might improve mental impairment and consequently health-related quality of life in survivors of severe acute respiratory distress syndrome" pps
... (PTSD) in long-term survivors of acute respiratory distress syndrome (ARDS). We wished to evaluate the influence of PTSD on HRQoL and to investigate the influence of perceived social support during ... support, empathy and helpful accepting behaviour of family caregivers during the life- threatening and traumatic ICU stay. Passive coping strategies, which ar...
Ngày tải lên: 13/08/2014, 03:20