Báo cáo khoa học: "Prognostic value of HMGB1 overexpression in resectable gastric adenocarcinomas" docx

... protein in the gastric adenocarcinomas Expression of HMGB1 protein was evaluated by using immunohistochemical staining. As a nonhistone DNA- binding protein, the expression of HMGB1 protein was mainly ... staining Rabbit-derived anti-human HMGB1 antibodies were used for IHC detection of HMGB1 protein in TMAs. TMA sections were processed for IHC demonstration of HMGB1...

Ngày tải lên: 09/08/2014, 03:21

... off, push the handle. In the following sections, I discuss the issues that arise in defining the logical form of these three types of sen- tences. The Davidsonian treatment of action sentences ... did not have these types of action in mind when suggesting his theory of logical form. In fact, a closer look at the literature shows that the problem of representing action se...

Ngày tải lên: 17/03/2014, 08:20

... contain world knowledge to filter out those interpretations that are meaningless in the discourse domain under consideration). Since the amount of processing involved in the application of ... without central determiner the source is the denotation of the head noun. For the indication of the quantity or fraction of that part of the source that is invol- ved in a pred...

Ngày tải lên: 24/03/2014, 01:21

... join these categories, since interspecific hybridization is by no means rare in butterflies (G UILLAUMIN & D ESCIMON , 1976). In any case, our observations once again ... dynamic nature of the evolutionary process. The remaining interesting case is whether the observed gene flow among these populations will lead to an incorporation of ge...

Ngày tải lên: 09/08/2014, 22:22

... pCR. Furthermore, combining PET and CT with fusing of function and morphologic data has increased the sensi- tivity and specificity in restaging of various malignant tumours including LARC after CRT. Recently, ... was lower in the responder group than in the non-responder. ROC analy- sis found SUV2 to be the best predictor of response. Using SUV2 value of 4,24 as the cut-off t...

Ngày tải lên: 09/08/2014, 09:20

... in only 22%) as well as in the maintenance phase (no adjuvant treatment in 79 % and a mean of 6 cycles in 21% of patients). However, inspite of this difference, outcome between the two dosing ... entity in upcoming studies. The low number of primary GBM exhibiting IDH1 mutations in our series indicates that our sample set consists indeed predominately of these tumors...

Ngày tải lên: 09/08/2014, 09:21

... proteins involved in growth regulation and survival may better serve to explain carcinogenesis in sarcomas. Conclusions The overexpression of STAT3 and pSTAT3 (Tyr705) has been observed in human ... Representative Western blotting analysis of STAT3 and pSTAT3 in soft tissue tumor extracts. Increased expression of STAT3 and pSTAT3 were observed in high and intermediate grade...

Ngày tải lên: 10/08/2014, 10:21

... or without hematoxylin staining. In hypoxia experiments, 3T3-L1 cells were maintained in a hypoxia chamber (Invivo 400; Ruskinn Inc., Cincinnati, OH, USA) constantly maintained at 1% O 2 . Culture medium ... cultured in DMEM containing 10% fetal bovine serum. OP9 cells were grown in aMEM containing 20% fetal bovine serum. C2C12 cells were maintained in DMEM containing 10% fetal bovi...

Ngày tải lên: 18/02/2014, 08:20

... interact with a number of functional groups, including the aromatic side chains of some amino acids, through a stacking mechanism [42]. The interaction of arginine with aromatic amino acids of aB-crystallin ... that aB-crystallin most likely employs various methods of binding (or binding modes) in order to prevent the aggregation of stressed proteins. Some of these binding mod...

Ngày tải lên: 18/02/2014, 16:20

... present a single, unique value of highest negative EIE, but two weak negative values of )13 and )10 kT. We noted that by summing up the two EIE max values, a value of EIE was obtained com- parable ... detected at the dimer interface of the models or in the surroundings of the hinge loop residues. Likewise, the models of nonex- changing and exchanging HHP-RNase were prepared...

Ngày tải lên: 19/02/2014, 06:20