... the substrate via two elements in ClpA, one in the N-domain and the other in the pore of the ClpA hexamer. In the case of short unstructured peptides or unfolded proteins such as casein, binding ... have analysed the role of five highly conserved basic residues in the N-domain of ClpA by monitor- ing the binding, unfolding and degradatio...
Ngày tải lên: 07/03/2014, 05:20
... ent. These arise with verbs of perceiving and certain others such as "permitting," when the substantive which is the direct object of the main verb is also the subject of the infinitive. ... the feminine singu- lar dative. 2. The masculine singular accusative of wel- cher is identical to the dative plural. 3. The nominative form is identical to the...
Ngày tải lên: 07/03/2014, 18:20
Báo cáo khoa học: An arginyl in the N-terminus of the V1a vasopressin receptor is part of the conformational switch controlling activation by agonist docx
... Biochem. 270) Ó FEBS 2003 An arginyl in the N-terminus of the V 1a vasopressin receptor is part of the conformational switch controlling activation by agonist Stuart R. Hawtin 1, *, Victoria J. Wesley 1 , ... UK Defining how the agonist receptor interaction differs from that of the antagonist receptor and understanding the mechanisms of recep...
Ngày tải lên: 07/03/2014, 21:20
Báo cáo khoa học: Local changes in the catalytic site of mammalian histidine decarboxylase can affect its global conformation and stability pptx
... for the dimer. Ó FEBS 2003 Conformational changes of histidine decarboxylase (Eur. J. Biochem. 270) 4379 Local changes in the catalytic site of mammalian histidine decarboxylase can affect its global ... decarboxylation and elimination of the fluoride, a reverse transaldimination can occur, so that an enamine form of the product can either l...
Ngày tải lên: 08/03/2014, 08:20
Báo cáo khoa học: Netropsin interactions in the minor groove of d(GGCCAATTGG) studied by a combination of resolution enhancement and ab initio calculations pot
... interactions FEBS Journal 272 (2005) 35313541 ê 2005 FEBS 3533 Netropsin interactions in the minor groove of d(GGCCAATTGG) studied by a combination of resolution enhancement and ab initio calculations Kristof ... (NAE) was investigated by evaluating the interaction energies and hydrogen positions of the end fragment and the bases of bas...
Ngày tải lên: 16/03/2014, 22:20
Báo cáo sinh học: " Molecular advances in the cell biology of SARS-CoV and current disease prevention strategies" doc
... Corresponding author AntiviralsCell biologyMolecular virologySARS-CoVVaccines Abstract In the aftermath of the SARS epidemic, there has been significant progress in understanding the molecular and cell ... SARS-CoV and the receptor-binding sites on the virion are located in the 12– 672 amino acid region of the S protein [43]. Current advances towards SA...
Ngày tải lên: 19/06/2014, 08:20
báo cáo hóa học:" Molecular advances in the cell biology of SARS-CoV and current disease prevention strategies" pot
... biologyMolecular virologySARS-CoVVaccines Abstract In the aftermath of the SARS epidemic, there has been significant progress in understanding the molecular and cell biology of SARS-CoV. Some of the ... surface. The virus enters the cell, uncoats, and the viral RNA is replicated and translated. The SARS-CoV U122 protein induces apoptosis in cells....
Ngày tải lên: 20/06/2014, 04:20
Báo cáo khoa học: "Recent advances in the surgical care of breast cancer patients" pps
... 5 years at the multivariate analysis [237]. In the US this information has resulted in a rapid increment of Breast Fellowship, recognizing that appro- priate training is one of the key factors in improving quality ... have resulted both in an increasing percentage of small breast cancers found at the initial diagnosis and in a small decline in mortality [2]. Howe...
Ngày tải lên: 09/08/2014, 03:21
Báo cáo khoa học: "Ruptured gallbladder as the first presentation of breast cancer" docx
... Perforation of the gall bladder as a first presentation of breast cancer has not been reported. Case presentation: Here we present a case of an elderly lady with acute abdomen with evidence of possible ... carcinomas of the breast have higher prevalence of spread to gastrointestinal tract compared to their ductal counterparts [1]. Although breast cancer metastasis...
Ngày tải lên: 09/08/2014, 04:21
báo cáo khoa học: "Recent advances in gastrointestinal oncology updates and insights from the 2009 annual meeting of the American Society of Clinical Oncology" doc
... REVIEW Open Access Recent advances in gastrointestinal oncology - updates and insights from the 2009 annual meeting of the American Society of Clinical Oncology Milind Javle 1 , Chung-Tsen Hsueh 2* Abstract We ... Clin Oncol (Meeting Abstracts) 2009, 27(18S):LBA4007. 56. Javle M, Hsueh CT: Updates in Gastrointestinal Oncology - insights from...
Ngày tải lên: 10/08/2014, 22:20
Báo cáo khoa hoc:" Functional polymorphisms in the promoter regions of MMP2 and MMP3 are not associated with melanoma progression" potx
... number not for citation purposes) Journal of Negative Results in BioMedicine Open Access Research Functional polymorphisms in the promoter regions of MMP2 and MMP3 are not associated with melanoma ... combined into a single variable, the 'phe- notypic index' [17]. This index, with minimum and max- imum values of 1 and 5, represents the...
Ngày tải lên: 11/08/2014, 08:21
Báo cáo khoa hoc:" Perfluorodecaline residue in the anterior chamber of a patient with an intact crystalline lens: a case report" ppt
... male with an intact crystalline lensFigure 2 Colour images of perfluorodecalin residue in anterior cham- ber of a 17-year-old male with an intact crystalline lens. Colour images of the retina ... before and after operationFigure 1 Colour images of the retina before and after operation. (a and b) Giant retinal tear with shallow detached retina involving...
Ngày tải lên: 11/08/2014, 10:23
báo cáo khoa học: " Recent advances in the genetics of language impairment" docx
... difficulties controlling the movement and sequencing of orofacial muscles, causing deficits in the production of fluent speech. In- depth studies of the KE family showed that, in these individuals, speech ... understanding of language disorders and improve our understanding of the biological foundations of language acquisition. â 2010 BioMed Central Ltd Recent...
Ngày tải lên: 11/08/2014, 12:20
báo cáo khoa học: " Pharmacogenomic considerations in the opioid management of pain" pot
... renal epithelial cells and also on the luminal side of endothelial cells in the blood-brain barrier, and it is a major determinant of the pharmaco- kinetics and pharmacodynamics of several opioids ... standard of care for anesthesiologists and pain management physi- cians. In the near future, pharmacogenomic approaches in pain management could lead to individual...
Ngày tải lên: 11/08/2014, 12:20
Báo cáo y học: " Recent advances in the investigation of curcuminoids" doc
... enhanced anti-inflammatory activity. The increased size of the cyclo- alkanone ring, by replacing the cyclopentanone in 27 with a cyclohexanone in 25, increased inhibitory potency. However, this ... HIV-1 integrase is the enzyme that catalyzes the integration of the double- strained DNA of HIV into the host chromosome [54]. Curcumin inhibited this activity of HIV-1 i...
Ngày tải lên: 13/08/2014, 15:21