báo cáo khoa học: "Clusterin confers gmcitabine resistance i

Báo cáo khoa học: "Whole shoot hydraulic resistance in Quercus species measured with a new high-pressure flowmeter" pps

... trend of declining stem component resistance to water flow with increasing age of the stem. In figure 2B the data are replotted to show the shoot resistance remaining after removal ... flow is contained in the above-ground portion of trees with perhaps 80% of the shoot resistance contained in the leaf blades. The remainder of the whole tr...

Ngày tải lên : 08/08/2014, 23:22

7
313
0

Báo cáo khoa học: Vitamin D stimulates apoptosis in gastric cancer cells in synergy with trichostatin A ⁄sodium butyrate-induced and 5-aza-2¢-deoxycytidine-induced PTEN upregulation ppt

... were therefore interested in determining whether TSA ⁄ - NaBu had any effects on promoting the binding of Egr-1, a major transcription factor of PTEN. To do this, we ﬁrst examined the in uences of ... inhibitor 5-aza-2¢-deoxycytidine played important roles in vitamin D-induced apoptosis through PTEN upregulation. The data presented in this article suggest potential beneﬁts of vitamin...

Ngày tải lên : 22/03/2014, 21:20

11
540
0

Báo cáo hóa học: " CCL20/CCR6 expression profile in pancreatic cancer" docx

... detected in all CP, PA and PCA specimens under investigation. In normal tissues, CCL20 staining was primarily found in pancreatic islet cells and rather sporadically in epithelial cells of pancreatic ... were routinely fixed in formalin and subsequently embedded in paraffin. Before staining, 4- μm thick paraffin-embedded tissue section were mounted on Superfrost Plus slides, d...

Ngày tải lên : 18/06/2014, 16:20

8
400
0

Tài liệu Báo cáo khoa học: A second independent resistance mechanism to Bacillus sphaericus binary toxin targets its a-glucosidase receptor in Culex quinquefasciatus docx

... and Bin-beads showed that this protein was functional, indicating that the Bin toxin binding site is located in the N-terminal half of Cqm1 (Fig. 5B, Rec-45S –). The speciﬁcity of the binding ... recombinant protein demonstrates that the binding site of the Bin toxin is located in this part of the receptor. To date, no informa- tion is available on the binding motif for the Bin toxin, and...

Ngày tải lên : 19/02/2014, 07:20

13
499
0

Tài liệu Báo cáo khoa học: Single phosphorylation of Tyr304 in the cytoplasmic tail of ephrin B2 confers high-afﬁnity and bifunctional binding to both the SH2 domain of Grb4 and the PDZ domain of the PDZ-RGS3 protein ppt

... of PDZ binding on the interactions of the Grb4-SH2 domain with the ephrinB2(301–333)-pY304 peptide. (A) The PDZ- binding curves are for the ﬂuorescein-labeled peptides including eph- rinB2(301–333) ... 301–333) of ephrin B2 confers high-aﬃnity binding to the SH2 domain of the Grb4 protein. Tyrosine phosphorylation at other candi- date sites resulted in only minor change of the binding of...

Ngày tải lên : 19/02/2014, 12:20

12
551
0

Tài liệu Báo cáo khoa học: Role of Kupffer cells in pathogenesis of sepsis-induced drug metabolizing dysfunction pptx

... shown that interactions between KCs and endotoxin comprise the initiating event lead- ing to hepatotoxicity in liver injury, including endotox- emia and ischemia ⁄ reperfusion injury [14]. In our studies, ... Regulation of hepatic drug-metabolizing enzyme genes by Toll-like receptor 4 signaling is independent of Toll-interleukin 1 receptor domain-containing adaptor protein. Drug Metab Dis...

Ngày tải lên : 14/02/2014, 18:20

11
769
0

Tài liệu Báo cáo khoa học: Transient RNA–protein interactions in RNA folding docx

... blocking or presenting of binding sites for the ribosome [4]. These are just a few Keywords mode of binding; proteins that promote RNA folding; RNA chaperones; RNA folding problem; transient interactions Correspondence B. ... helicases. The binding sites for double- stranded RNA and ATP overlap, resulting in coupled binding of both molecules. Simultaneous binding forces the RNA into a bent...

Ngày tải lên : 14/02/2014, 19:20

9
600
1

Tài liệu Báo cáo khoa học: Interruption of triacylglycerol synthesis in the endoplasmic reticulum is the initiating event for saturated fatty acid-induced lipotoxicity in liver cells pdf

... variety of cell types, including hepatocytes, to long-chain saturated fatty acids (SFAs) led to increased expression of proin- ﬂammatory cytokines, inhibition of insulin signaling, induction of endoplasmic ... Osaka, Japan) carcinoma cells were grown in DMEM containing 10% heat-inactivated fetal bovine serum, 2 mm glutamine, 100 UÆmL )1 penicillin, and 100 ngÆmL )1 streptomycin, at 37 °C i...

Ngày tải lên : 14/02/2014, 22:20

12
721
0

Tài liệu Báo cáo khoa học: Epidermal growth factor receptor in relation to tumor development: EGFR gene and cancer ppt

... ligand-binding domain; a transmembrane domain; an intracellular tyrosine kinase domain; and a C-terminal regulatory domain [2]. The extracellular domain is subdivided further into four domains. ... EGFR (including EGF, transforming growth factor-a, amphi- regulin and epigen); (b) those that bind to EGFR and ERBB4 (including betacellulin, heparin-binding EGF and epiregulin); and (c) neuregulin...

Ngày tải lên : 16/02/2014, 09:20

8
684
0

Tài liệu Báo cáo khoa học: Epidermal growth factor receptor in relation to tumor development: EGFR-targeted anticancer therapy doc

... compete with ATP for binding to the tyrosine kinase pocket of the receptor, thereby inhibiting receptor tyrosine kinase activity and EGFR signaling pathways (Fig. 1). Early clinical studies showed ... extracellular domain of the receptor, thereby inhibiting ligand-dependent EGFR signal transduction; and small- molecule tyrosine kinase inhibitors, such as geﬁtinib and erlotinib, which target t...

Ngày tải lên : 16/02/2014, 09:20

7
511
0

báo cáo khoa học: "Clusterin confers gmcitabine resistance in pancreatic cancer" pps

Báo cáo khoa học: "Whole shoot hydraulic resistance in Quercus species measured with a new high-pressure flowmeter" pps

Báo cáo khoa học: Vitamin D stimulates apoptosis in gastric cancer cells in synergy with trichostatin A ⁄sodium butyrate-induced and 5-aza-2¢-deoxycytidine-induced PTEN upregulation ppt