Báo cáo y học: "Infliximab therapy in rheumatoid arthritis and ankylosing spondylitis-induced specific antinuclear and antiphospholipid autoantibodies without autoimmune clinical manifestations: a two-year prospective study" potx

... of ANA and anti-dsDNA autoantibodies and demonstrated that the induction of ANA, anti-dsDNA and aPL autoantibodies is related to infliximab treatment in both RA and AS, with no significant relationship ... 1- year intervals. ANA, anti-dsDNA and aPL were the only autoantibodies to be significantly induced by infliximab treatment in RA and AS patients. This induction has a...

Ngày tải lên: 09/08/2014, 01:24

... Anticitrullinated protein/peptide antibody assays in early rheumatoid arthritis for predicting five years radiographic damage. Ann Rheum Dis 2003, 62:120-126. 19. Bas S, Genevay S, Meyer O, Gabay C: Anti-cyclic citrullinated peptide ... 48:1165-1166. Available online http:/ /arthritis- research.com/content/6/3/R264 R268 Autoantibody associated clinical manifestations A 34-year-old w...

Ngày tải lên: 09/08/2014, 01:23

... surgery and 109 myceto- mas of paranasal sinuses. Laryngoscope 1997, 107:112-117. 28. Dahniya MH, Makkar R, Grexa E, Cherian J, al-Marzouk N, Mattar M, Saghir E, Fathi al-Samman T: Appearances ... anemia, osteopenia Glucocorticoid therapy, methotrexate, salazopyrine Yes a Rheumatoid arthritis (RA) duration at aspergilloma diagnosis. Table 2 Previous otorhinolaryngological disease...

Ngày tải lên: 09/08/2014, 14:22

... with RA, infiltrating T and B lym- phocytes accumulate underneath the synovial lining layer and organize into lymphocyte aggregates with germinal centres (GCs) [19–21]. These ectopic lymphoid ... macrophage inflammatory protein-1α (MIP- 1α or CCL3) in RA synovial tissue, and that elevated levels of these chemokines are also detected in RA syn- ovial fluids [9]. IL-8 and ENA-78, wh...

Ngày tải lên: 09/08/2014, 03:24

... Detailed clinical and labo- ratory data, and serial radiographs of hands and feet were available for all patients (see Table 1). Serum and whole blood samples were obtained from each patient. Laboratory ... e-mail: haentzho@medizin.uni-leipzig.de Supplementary material Supplementary Materials and methods Serum concentrations of RF IgM and IgA were determined using a standard E...

Ngày tải lên: 09/08/2014, 03:24

... eventually clinically recognizable ventricular dysfunction (Fig. 1). Inflammatory pathways and myocardial remodeling The process by which cardiac structure and function adapts to physiologic changes ... ‘myocardial remodeling’ and involves the cellular and interstitial changes leading to myocyte hypertrophy, ventricular dilatation, alterations in interstitial collagen superstructure...

Ngày tải lên: 09/08/2014, 07:20

... Akiko Senuma 2 and Yoshiaki Ishigatsubo 3 1 Intractable Disease Center, Yokohama City University Medical Center, Yokohama, Japan 2 Department of Rheumatology, Yokohama Minami Kyousai Hospital, ... Kyousai Hospital, Yokohama, Japan 3 Department of Internal Medicine and Clinical Immunology, Yokohama City University Graduate School of Medicine, Yokohama, Japan Corresponding author: Haruko...

Ngày tải lên: 09/08/2014, 08:22

... of infection and malignancy. Introduction Rheumatoid arthritis (RA) is a progressive destructive inflammatory disease associated with pain and disability. It has a significant negative impact ... infliximab groups. More patients receiving infliximab had clinically Review Aspects of early arthritis Biological therapy in early arthritis – overtreatment or the way to go? Kei...

Ngày tải lên: 09/08/2014, 10:20

... skin fibrosis. Arthritis Rheum 2007, 56:2755-2764. 21. Nasu Y, Nishida K, Miyazawa S, Komiyama T, Kadota Y, Abe N, Yoshida A, Hirohata S, Ohtsuka A, Ozaki T: Trichostatin A, a histone deacetylase ... process is mainly catalyzed by two main RNAse III-type endonucleases of which Drosha acts in the nucleus whereas Dicer acts in the cytoplasm. Mature miRNAs that are incorporated into...

Ngày tải lên: 09/08/2014, 13:21

... work? Maria JH Boumans and Paul P Tak Division of Clinical Immunology and Rheumatology, Academic Medical Center/University of Amsterdam, 1100 DE Amsterdam, the Netherlands Corresponding author: Paul ... cells in the pathogenesis of RA had previously been suggested by the association with auto- antibodies (rheumatoid factor and anti-citrullinated protein antibodies), which can be fo...

Ngày tải lên: 09/08/2014, 14:22