Báo cáo y học: "Critical role of the major histocompatibility complex and IL-10 in matrilin-1-induced relapsing polychondritis in mice" doc

... MIRP induction, and IL-10 plays a major suppressive role in cartilage inflammation of the respiratory tract. Keywords: IL-10, matrilin-1, matrilin-1-induced relapsing polychondritis, major histocompatibility ... reported on the role of cytokines in RP, either in patients or in the corresponding animal models. In the CIA model, several cytokines have b...

Ngày tải lên: 09/08/2014, 01:24

... activity encoded by the ATF2 gene. Therefore, both free pregnenolone production and the efficient coupling of the SCC and the 3b-HSD activities in yeast require the use of strains lacking this acetylating ... recombinant yeast. In conclusion, the SCC reaction appears to be regulated similarlyinyeastandinadrenalcells;inthelatter,Adxpand not Adrp limits the activity of...

Ngày tải lên: 08/03/2014, 08:20

... chance for reentry at another workplace. Unfortunately, there are often delays in the diagnosis of OA, and the diagnosis may not be reached until several years after the onset of symptoms. 7 A recent ... associated symptoms of allergic rhinitis and conjunctivitis. A history of accidental high respiratory irritant exposure shortly before the initial onset of symp- toms...

Ngày tải lên: 08/08/2014, 21:20

... Groningen, the Netherlands) in order to obtain a recombinant protein containing the C-myc epitope followed by six histidines at the C-terminus. A plasmid containing the wild type version of CCR5 ... glycosaminoglycans [37]. As the myc-his tag of the protein was present at the C-terminus of the receptor which is located on the inside of the cell, we then determine...

Ngày tải lên: 08/03/2014, 09:20

... cap- binding by eIF4E [54] indicating that the eIF4F complex will likely stay intact (note that the binding of either 4E-BP1 or eIF4G to eIF4E appears to be the determining factor in stabilizing the ... the ribose and Trp56 (not indicated). Other direct interactions involve the phosphate groups of the ligand and Lys162 (not indicated), Arg157 and Lys159 (as indicat...

Ngày tải lên: 23/03/2014, 21:20

... high and constant level of c-Myc. Also, the contribution of Ras/Raf/ERK prevented the rapid degradation of c-Myc by phosphorylation of the serine 62 residue in the N-terminal of c- Myc [24]. They ... hypothesized that c-Myc plays a central role in TGF1 signaling for cell growth stimulation. Additionally, to examine the possibility of involvement of the MAPK...

Ngày tải lên: 09/08/2014, 01:22

... of YgfZ followed by Figure 2 Different roles played by YgfZ and SodA in counteracting plumbagin. The ΔygfZ and ΔsodA strains were transformed with pQE- sodA and pQE-ygfZ to express SodA and YgfZ, ... and the Δyg fZ strains and the parental strain were tested (Table 3). Therefore, adding a methyl group to the 3-position of naphtho quinone ring apparently diminishes t...

Ngày tải lên: 10/08/2014, 05:21

... by sub-acu te and chronic low back pain and/ or sciatica: this exerts an important impact on the quali ty of life, causing interfer- ence of sleep and enjoyment of life. Many clinical studies ... of Physical Medicine and Rehabilitation, University of Foggia, Foggia, Italy Full list of author information is available at the end of the article Ranieri et al. Journal...

Ngày tải lên: 10/08/2014, 10:20

... Biol Ther 2003; 2: 491-9. 16. Huang S, Shao G, Liu L. The PR domain of the Rb-binding zinc finger protein RIZ1 is a protein binding interface and is related to the SET domain functioning in ... types of PRDMs have been identified in humans [15, 18]. Most of them are located near the N-terminal portion of the proteins followed by zinc-fingers, and are involved...

Ngày tải lên: 25/10/2012, 11:15