Báo cáo y học: "Increased circulating levels and salivary gland expression of interleukin-18 in patients with Sjögren''''''''s syndrome: relationship with autoantibody production and lymphoid organization of the periductal inflammatory infiltrate" pptx
Báo cáo y học: "Increased circulating levels and salivary gland expression of interleukin-18 in patients with Sjögren''''s syndrome: relationship with autoantibody production and lymphoid organization of the periductal inflammatory infiltrate" pptx
... of IL-18 in this cell type is in Figure 4Degree of lymphoid organization of the periductal lymphocytic infiltrates in salivary gland of patients with Sjögren's syndrome (SS)Degree of lymphoid ... IL-18. Relationship between IL-18 expression and lymphoid organization of inflammatory foci in salivary glands of patients with SS in comparison with secondary lymphoid organs Expression of IL-18 ... with the degree of lymphocytic infiltration in sali-vary gland, a finding that indirectly suggests that the increase in lymphocytic infiltration is accompanied by the up-regulation of Th1 cytokines...
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Báo cáo y học: " Lymphocyte Responses to Chymotrypsin- or Trypsin VDigested b-Lactoglobulin in Patients with Cow’s Milk Allergy" doc
... examined by CAP-RAST.Preparation of BLG Peptides Digested byChymotrypsin or Trypsin VWe focused on the allergenicity of BLG and made twokinds of BLG peptides. We used chymotrypsin and trypsinV ... peptides. Trypsin V is a mixture of chymotrypsin and trypsin. Figure 1 shows the digestivesites of BLG polypeptides by these enzymes. Digestion with chymotrypsin resulted in small peptides ranging from ... usedtrypsin V-digested BLG peptides. Since trypsin V containsa mixture of trypsin and chymotrypsin, the resultantpeptides were smaller than peptides digested by chymo-trypsin or trypsin.Lymphocyte...
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Báo cáo y học: "A randomised, double-blind, placebo-controlled trial of tropisetron in patients with schizophrenia" pps
... receiving stabledoses of all of these medications in the 4 weeks preceding the trial and throughout the entire duration of the study. In all, 10 patients in the placebo group and 11 patients in the ... stimulation[17]. Therefore, it is of great interest to study whether the density of α7 nAChRs is altered in the intact brain of patients with schizophrenia. A positron emission tomog-raphy (PET) study using ... will be necessary. Another possibil-ity is that there was incomplete absorption of a singledose of varenicline, leading to insufficient levels of the drug in the brain [46]. Furthermore, Freedman...
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Báo cáo y học: "Intra-abdominal hypertension due to heparin induced retroperitoneal hematoma in patients with ventricle assist devices: report of four cases and review of the literature" pdf
... and reduction in urinary output [23,26,27]. Neverthelessinteresting is the fact that renal failure in the absence of pulmonarydysfunctionisnotlikelytobetheresultofIAH [22].Because many of the effects of ... IAHaccording to the World Society of the Abdominal Com-partment Syndrome. The mortality rate in patients with IAH and ACS varies from 29 to 62% and is u sually dueto multiple organ failure and sepsis ... mildtachycardia are most of the time present. Any abnorma l and sudden increase in the volume of any component of the intra-peritoneal or extra-peritoneal spaces can causeIntra-abdominal Hypertension....
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Báo cáo y học: "κ Increased AP-1 and NF-κB activation and recruitment with the β combination of the proinflammatory cytokines IL-1β, tumor necrosis factor alpha and IL-17 in rheumatoid synoviocyte" ppt
... infiltration of the synovial membrane with monocytes/T cells, by the proliferation of synovial liningcells and by the production of proinflammatory cytokines,which contribute to cartilage and bone ... than the combined inhibition of IL-1β and TNF-α.Since AP-1 and NF-κB are common pathways for thesecytokines, neutralizing these TFs directly or by acting on theirupstream kinases may have an increased ... in RA synoviocytesT cells and monocytes are two major cell types involved in RA pathogenesis. Some of their derived cytokines may bepresent at very low concentrations in the RA joint, and their...
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Báo cáo y học: "Increased serum levels of macrophage migration inhibitory factor in patients with primary Sjögren''''s syndrome" potx
... serum levels of MIF in patients with pSS and the relation of these levels to clinical and laboratory findings. In addition, we analysed associations of MIF concentrations with various cytokines ... original work is properly cited.Abstract The objective of this study was to analyse levels of the proinflammatory cytokine macrophage migration inhibitory factor(MIF) in patients with primary ... helper type 1 cytokine expression as well as B-lymphocyte hyperactivity leading to the production of circulating autoantibodies and hypergamma-globulinemia are hallmark characteristics of the disease.Macrophage...
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Báo cáo Y học: Purification, characterization and subunits identification of the diol dehydratase of Lactobacillus collinoides pot
... enzymerequired the adenosylcobalamin coenzyme for catalyticactivity and the Kmfor the cofactor was 8 lM. Inactivation of the enzyme was observed by both glycerol and cyano-cobalamin. The ... is catalysed by a dehydratase that convertsglycerol to 3-hydroxypropionaldehyde, a precursor of acrolein [12]. The dehydratase enzyme plays therefore akey role in the development of the alteration ... expression of the L. collinoidesdioldehydratase The three genes pduCDE encoding the three subunits of the diol dehydratase were cloned in the pQE30 expression vectorsystem. The synthesis of the three...
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Báo cáo y học: "Association between antipsychotics and weight gain among psychiatric outpatients in Pakistan: a retrospective cohort study" ppsx
... details includ-ing the medication prescribed, of patients presenting to the psychiatry clinics at the AKUH for the first time. All patients have their height recorded on the first visit and weight ... with increase in weight and body mass index (BMI) in this population.Methods The study was a case note review of all patients who hadbeen prescribed antipsychotic medication in the psychia-try ... and ≥27.5, representing the categories of being underweight,increasing but acceptable risk, increased risk, and higherrisk, respectively. We have used the same cut-offs in thisstudy.An increase...
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Báo cáo y học: "Improved cartilage integration and interfacial strength after enzymatic treatment in a cartilage transplantation model" potx
... (b) Collagen type II, showing medium intensity staining (in red) in the entire matrix of the interfacial area. (c) Collagen type III; staining (in red) only present in the surrounding capsule. ... 10interfaces in the treated group and three out of 10 inter-faces in the control group). Typically, this ingrowth wasaround 10% of the interface length, with Fig. 4a showing the worst case. Furthermore, ... constructsImmunohistochemical stainings for collagens present in the interfacial area of enzyme-treated constructs. (a) Collagen type I, with light staining (in red) in the area of fibrous ingrowth (circled)....
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Báo cáo y học: "Delayed intracardial shunting and hypoxemia after massive pulmonary embolism in a patient with a biventricular assist device" pdf
... set-ting with adjustments of PEEP and peak inspiratory pres-sure did not lastingly improve oxygenation.Transesophageal echocardiography detected atrial levelintracardial shunting (Figure 2). There ... imaging and contrast with agitated saline i s highly recommended before cardiopul-monary bypass and after LVAD activation [12,13]. Alter-natively, manual occlusion of the pulmonary arteryshortly ... after the event [16].Emergency surgical embolectomy is recommended in hemodynamic unstable patients with massive pulmonaryembolism in a facility with cardiac surgical capabilities[17]. Catheter...
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