Báo cáo y học: "4th meeting of the EU research network EUROME: From the identification of genes and cellular networks in murine models of arthritis to novel therapeutic intervention strategies in rheumatoid arthritis, London, UK, 9 March 2004" pot

... network EUROME: From the identification of genes and cellular networks in murine models of arthritis to novel therapeutic intervention strategies in rheumatoid arthritis, London, UK, 9 March 2004 Saleh ... Kennedy Institute of Rheumatology at Imperial College, London, on 9 March 2004. Genetic approaches to therapy for rheumatoid...

Ngày tải lên: 09/08/2014, 01:23

... YSYTATYHIYDLTNGEFIR 1 098 .96 (2+) 403–421 VTQDSLFYSSNEFEGYPGR The 97 kDa band obtained following biotinylated fluorophosphonate labelling of bovine chondrocytes was trypsin digested and analysed ... protein profiling: the serine hydrolases. Proc Natl Acad Sci USA 199 9, 96 :14 694 -14 699 . 14. Kidd D, Liu Y, Cravatt BF: Profiling serine hydrolase activities in complex proteome...

Ngày tải lên: 09/08/2014, 07:20

... protein, which bind to (1fi3)-b- D -glucans, e.g. curdlan or laminarin. After binding of the carbohydrate to the receptor, the expression of the gene coding for the binding protein increases. In ... taxa to echinoderms [65] or ascidians [21] in the deuterostomian branch, and to the horseshoe crabs [20] in the protostomian line; this domain is thought to pl...

Ngày tải lên: 16/03/2014, 16:20

... Fujimoto S, Oku A, Tsuda K, Toyokuni S, Hiai H, Mizunoya W, Fushiki T, Holst JJ, Makino M, Tashita A, Kobara Y, Tsubamoto Y, Jinnouchi T, Jomori T, Seino Y: Inhibition of gastric inhibitory polypeptide ... enzymatic activity. Inactivation of the miR-30 family drastically reduced GPDH activity at day 10 (fold reduction of 23 .9) . Interestingly, over-expression of miR-30a and m...

Ngày tải lên: 09/08/2014, 23:20

... revascularization in coronary patients is one of the main goals in coronary surgery, use of Mini-HLM and thus minimizing the side effects of CCPB is a desirable modern approach. In today´s economically affected ... stimulus of a generalized inflammatory state and thus having the potential to result in significant morbidity [1]. In order to decrease morbidity...

Ngày tải lên: 10/08/2014, 09:22

... from 199 9 to 2010 were identified and synthesized to compare the efficacy and safety of LVRS vs conservative medical therapy. One RCT was obtained regarding comparison of median sternotomy ... mortality in 3 months (including Fishman’s study); B: mortality in 6 months; C: mortality in 12 months(including Fishman’s study); D mortality in 3 months (excluding Fishma...

Ngày tải lên: 10/08/2014, 09:22

... preliminarily selected Cys2 59, Cys261 and Cys262 in the C-terminal region of the enzyme and prepared two mutants, C259S ⁄ C261S and C262S. We selected Cys2 59 and Cys261, as a disulfide (Cys246- Cys248) ... is localized in the C-terminal region and that the C-terminal peptide is necessary for the integrity of the active site. More- over, the binding of 5¢-de...

Ngày tải lên: 16/03/2014, 18:20

... on the different phosphorylation of MAP kinase. Effects of MAP kinase inhibitors on DNA synthesis in HCS-2/8 and RGC cells To investigate the signal pathways for proliferation of chondrocytes induced ... Dudley, D.T. & Saltiel, A.R. ( 199 5) PD 098 0 59 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. J....

Ngày tải lên: 24/03/2014, 04:21

... significantly affects adsorption of the enzyme on crystalline cellulose, but has no effect on the hydrolysis of xyloglucan, indicating that the domain may contribute to the localization of the enzyme. ... domain and the C-terminal domain belonging to the carbohydrate- binding module (CBM) family 1 [21,22]. In the present study, we have heterologously expressed th...

Ngày tải lên: 30/03/2014, 03:20

... 2000), 173–1 79. 352 sibility and authority in defining and approving the use of new words. The process of defining a new word is manual and time-consuming as each word must be approved by a working group of ... each string, S 1 to S N and records the longest string pat- tern which occur in both S j and the other string in the set. On the other hand, the m...

Ngày tải lên: 31/03/2014, 01:20