Báo cáo y học: "Diosgenin, a plant steroid, induces apoptosis in human rheumatoid arthritis synoviocytes with cyclooxygenase-2 overexpression" pdf
Báo cáo y học: "Diosgenin, a plant steroid, induces apoptosis in human rheumatoid arthritis synoviocytes with cyclooxygenase-2 overexpression" pdf
... summarizing major events in diosgenin-induced apoptosis in human rheumatoid arthritis (RA) fibroblast-like synoviocytes (FLS)Diagram summarizing major events in diosgenin-induced apoptosis in human ... mediated by the cysteine protease family called caspases, such as caspase-3, which is the major executioner of apoptosis. In our study, caspase-3 activity and DNA fragm...
Ngày tải lên: 09/08/2014, 01:23
Báo cáo y học: " Tumour necrosis factor-α stimulates dehydroepiandrosterone metabolism in human fibroblast-like synoviocytes: a role for nuclear factor-κB and activator protein-1 in the regulation of expression of cytochrome p450 enzyme 7b" doc
... pre- viously investigated the relation between Cyp7b activity and arthritis. We showed that the severity of murine collagen- induced arthritis was associated with an increase in Cyp7b activity and Cyp7b ... van der Vleuten MAJ, Kavelaars A, Heijnen CJ, Boots AM: CYP7B expression and activity in fibroblast-like synoviocytes from patients with rheumatoid arthritis: regulation b...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo y học: "Inhibition of protein geranylgeranylation induces apoptosis in synovial fibroblasts" pdf
... by statins in RA synovial fibroblasts We next examined intracellular signaling pathways implicated in RA synovial fibroblast survival. Lovastatin decreased the steady-state pAkt levels at least ... activated Akt pathway is affected by lovastatinThe steady-state and activated Akt pathway is affected by lovastatin. Rheumatoid arthritis synovial fibroblasts (2 lines shown) were cultured...
Ngày tải lên: 09/08/2014, 08:22
Báo cáo y học: "Candidate autoantigens identified by mass spectrometry in early rheumatoid arthritis are chaperones and citrullinated glycolytic enzyme" pot
... Suzuki A, Sawada T, Ohtake-Yamanaka M, Inoue T, Hasebe T, Yamada R, Yamamoto K: Identification of citrullinated eukaryotic translation initiation factor 4G1 as novel autoanti- gen in rheumatoid arthritis. ... Arthritis Res Ther 2005, 7:R1421-R1429. 11. Suzuki A, Yamada R, Ohtake-Yamanaka M, Okazaki Y, Sawada T, Yamamoto K: Anti-citrullinated collagen type I antibody is a tar- get...
Ngày tải lên: 09/08/2014, 13:22
Báo cáo y học: "Hypoalbuminaemia – A Marker of Cardiovascular Disease in Patients with Chronic Kidney Disease Stages II - IV"
... that hypoalbuminaemia can be more appropriately viewed as a composite marker which reflects malnutrition as well as increased acute phase inflammation, considering that albumin is also a negative ... Owen et al (33) demonstrated that hypoalbu- minemia was a strong predictor of mortality in dialysis patients. Kalantar-Zadeh et al (34) also showed higher mortality in dialysis pa...
Ngày tải lên: 03/11/2012, 11:52
Báo cáo y học: "Response to the commentary ‘Pooled indices to measure rheumatoid arthritis activity: a good reflection of the physician’s mind" pdf
... by Aletaha [1] on a recent report from our group [2]. First, Aletaha states that evaluation of the ‘physician’s mind’ is best performed in a study setting in which the physician is unaware that ... duration 10 years) and had previously failed to respond to aggressive therapy, as reflected by a failure to respond to a median of four disease-modifying antirheumatic drugs. Infliximab...
Ngày tải lên: 09/08/2014, 08:22
Báo cáo y học: "Protein, iron, and meat consumption and risk for rheumatoid arthritis: a prospective cohort study" pps
... die- tary patterns of individual women, our primary analysis used cumulative average food and nutrient intakes from all available dietary questionnaires up to the start of each 2-year interval [24]. ... menses from age 20 to 35 years (very regular, usually regu- lar, usually irregular, and very irregular) in 1982. Statistical analyses The number of person-years of follow up was ascertained...
Ngày tải lên: 09/08/2014, 10:20
Báo cáo y học: "Activation of proteinase-activated receptor 2 in human osteoarthritic cartilage upregulates catabolic and proinflammatory pathways capable of inducing cartilage degradation: a basic science study" pot
... statistical analysis, and manuscript preparation. NA participated in acquisition of data, analysis and interpretation of data, statistical analysis, and manuscript preparation. JMP and JPP participated ... participated in study design, analy- sis and interpretation of data, and manuscript preparation. ND participated in study design and in analysis and interpretation of data. HF parti...
Ngày tải lên: 09/08/2014, 10:22
Báo cáo y học: "Is a purpose of REM sleep atonia to help regenerate intervertebral disc volumetric loss" pdf
... citation purposes) stand clearly the gravitational influences on all adjacently associated mammalian structural tissues related to these muscles across day and night. The spine plays a founda- tional ... showing their deformation with daily variations. Therefore, there are two combined forces working against the task of maintaining hydraulic vertebral spacing: 1) stabilizing musculature a...
Ngày tải lên: 10/08/2014, 09:20
Báo cáo y học: "Characterization of erythrovirus B19 genomes isolated in liver tissues from patients with fulminant hepatitis and biliary atresia who underwent liver transplantation"
... Transplantation Surgery, Nagoya University Hospital, Aichi, Japan 3. Department of Transplantation Surgery, Kyoto University Hospital, Kyoto, Japan 4. Institute of Biomedical Research and Innovation, ... DNA by PCR assay. However, the cause of fulminant hepatitis and biliary atresia in many patients is unexplained and this is a serious issue, especially in newborns and in- fants....
Ngày tải lên: 26/10/2012, 10:03