... wasbased on routinely processed hematoxylin-eosin stainsand confirmed by immunohistochemical staining look-ing for pan-cytokeratin, cytokeratin 5 and 7, chrom-ogranin A, synaptophysin and tissue-transcripion-factor-1. ... agents, which selectively target cell cycle pro-teins. For example, flavopiridol has the ability to inducecell cycle arrest by binding and inhibiting different cyclin-dependent kinase such as 2 and ... PRKCI (protein kinase C, iota), PLS3(plastin 3), PTTG1 (pituitary tumor-transforming 1),PTTG1-IP (pituitary tumor-transforming 1 binding pro-tein), UBE2C (ubiquitin-conjugating enzyme E2C),MAGED4...