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Báo cáo y học: "Nifedipine decreases sVCAM-1 concentrations and oxidative stress in systemic sclerosis but does not affect the concentrations of vascular endothelial growth factor or its soluble receptor" potx

Báo cáo y học:

Báo cáo y học: "Trace Elements, Heavy Metals and Vitamin Levels in Patients with Coronary Artery Diseas"

... studies investigating whether Fe status or dietary Fe intake is associated with an in- creased risk of MI or CAD have not supported the hypothesis that high body Fe stores increase the risk of ... CAD and 20 pa-tients having normal coronary arteries attending car-diology clinic at Yuzuncu Yil University Hospital. The study was approved by the local ethics committee according to the ... results; these may in part be explained by the use of nonspesific measures of body Fe stores, such as serum transferrin (16-19). The strongest supporting evidence that Fe is a risk factor for...
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Báo cáo Y học: Amino acids 3–13 and amino acids in and flanking the 23FxxLF27 motif modulate the interaction between the N-terminal and ligand-binding domain of the androgen receptor pdf

Báo cáo Y học: Amino acids 3–13 and amino acids in and flanking the 23FxxLF27 motif modulate the interaction between the N-terminal and ligand-binding domain of the androgen receptor pdf

... acids 3–13 and amino acids in and flanking the 23FxxLF27motif modulate the interaction between the N-terminal and ligand-binding domain of the androgen receptorKarine Steketee1,*, Cor A. Berrevoets2,*, ... assays is the coupling of AR.NTD to GalAD in the yeast assay, and the absence of a second transactivationdomain linked to AR NTD in the mammalian assay. The latter assay completely depends on the ... stabilization of the in vivo N/Cinteraction, which are not reflected in the pull-down assays and peptide interaction experiments. Unfortunately, the Fig. 3. AR3–13 is not involved in direct binding of AR...
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Tài liệu Báo cáo khoa học: Parvalbumin deficiency in fast-twitch muscles leads to increased ‘slow-twitch type’ mitochondria, but does not affect the expression of fiber specific proteins doc

Tài liệu Báo cáo khoa học: Parvalbumin deficiency in fast-twitch muscles leads to increased ‘slow-twitch type’ mitochondria, but does not affect the expression of fiber specific proteins doc

... found in WT TA and not at muchlower levels, as seen in SOL. These findings furthersupport the presence of distinct pathways regulatingfiber specific isoforms and metabolic enzymes, on the one hand, ... B, Meyer M & Schiffmann SN (2002) ‘New’functions for ‘old’ proteins: The role of the calcium-binding proteins calbindin D-28k, calretinin and parval-bumin, in cerebellar physiology. Studies ... virtually identicalwith the exception of the lack of the PV spot in PV– ⁄ –mice (Fig. 2A–C). This indicates that expression of fiber type specific MLC isoforms is not affected by PVdeficiency, in line...
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Báo cáo khoa học: Estrogen-related receptor a and PGC-1-related coactivator constitute a novel complex mediating the biogenesis of functional mitochondria potx

Báo cáo khoa học: Estrogen-related receptor a and PGC-1-related coactivator constitute a novel complex mediating the biogenesis of functional mitochondria potx

... condition by the uncou-pling of oxidative phosphorylation with FCCP(maximal respiratory) and the nonphosphory-lating respiratory condition with oligomycin(oligomycin-insensitive). Phosphorylating ... viable[10,32] and the inhibition of ERRa in other cell models decreases the respiratory parameter only partially [9].This suggests that other factors are involved in the con-trol of oxidative phosphorylation, ... FTC-133 thyroid cell line, the inhibition of ERRa may lead to a slowing down of cell growth, partly by decreasing the respiratory capacity and phosphorylating respiration. In conclusion, the ERRa–PRC...
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báo cáo hóa học:

báo cáo hóa học:" Risk factor analysis for early femoral failure in metal-on-metal hip resurfacing arthroplasty: the effect of bone density and body mass index" potx

... thresholds of each risk factor and thecombined factors in order to provide more meaningful information for surgeons for clinical use. Results The Harris hip scores for patients significantly improved ... already surpassed the learning curve of hip resurfacing procedures prior to this study. Beginning in July 2006, we routinely recorded bone mineral density with the use of a dual energy x-ray absorptiometry ... takes form as acute fracture or gradual collapse of the femoral head within the first two years. Normally, studies combine all types of failures when analyzing the risk factors for HRA. It is not...
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Báo cáo y học:

Báo cáo y học: "Pravastatin Provides Antioxidant Activity and Protection of Erythrocytes Loaded Primaqe"

... up the membrane integrity [34]. The major alteration in the shape of erythrocytes is the spherocytes formation in the presence of pri-maquine. These observations are supported by the work ... in the current studies upon loading to erythrocytes. The erythrocytes were classified into; control erythrocytes, erythrocytes incubated with either 2 mM of PS or 2 mM of PQ, and erythrocytes ... primaquine and their combinations respectively. On another side the maximum hemolysis of 94.8% for control erythro-cytes, 98.4% for pravastatin, 99.5% for primaquine and 95.2% for the combination...
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Báo cáo y học:

Báo cáo y học: "Parvovirus B19 Genotype Specific Amino Acid Substitution in NS1 Reduces the Protein’s Cytotoxicity in Culture"

... in the reduction of B19 NS1-induced cytotoxicity of liver cells. Our results support the hypothesis that in the setting of persistent B19 infection, direct B19 NS1-induced cytotoxicity may play ... Cotmore SF, Tattersall P. Sequence motifs in the replicator protein of parvovirus MVM essential for nicking and covalent attachment to the viral origin: identification of the linking tyrosine. ... (AMS Biotechnology LTD., Abington, OX, UK), incubated for 15 min at room temperature in the dark and immediately ana-lyzed by flow cytometry. The percentage of cells ex-pressing the EGFP marker,...
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Báo cáo y học:

Báo cáo y học: "Childhood Febrile Seizures: Overview and Implications"

... shake and move limbs on both sides of the body. The child becomes rigid or has twitches in only a portion of the body, such as an arm or a leg, or on the right or the left side only. The child ... restrain the child or stop the seizure movements. Don't try to force anything into his mouth to prevent him from biting his tongue as this increases the risk of injury. Move the child only ... and/ or testing of the child Blood and urine tests may be examined to detect infections. Typically, a full seizure workup includ-ing an EEG, head CT, and lumbar puncture (spinal tap ) is not warranted....
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Báo cáo y học:

Báo cáo y học: "Rasburicase represents a new tool for hyperuricemia in tumor lysis syndrome and in gout Lisa Cammalleri and Mariano Malaguarnera"

... for DNA and RNA synthesis, and inosine that will be degraded into hypoxanthine and xanthine and finally into uric acid. Hypoxanthine and guanine may enter in a sal-vage pathway, using hypoxanthine-guanine ... analogous of hypoxanthine, inhibitor of xanthine oxi-dase, the last enzyme involved in uric acid synthesis pathway. It catalyzes the conversion of hypoxanyhine into xanthine and this latter into ... raises the risk of morbidity and mortality, even in patients potentially curable. TLS is defined as the presence of at least 2 of the following laboratory data: hyperuricemia, hyper-kalemia, hyperphosphatemia,...
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 Báo cáo y học:

Báo cáo y học: "Low socio-economic status, smoking, mental stress and obesity predict obstructive symptoms in women, but only smoking also predicts subsequent experience of poor health"

... status of the original cohort (born in 1930) at the time of the 32-year follow-up is presented in Table 1. Details of the sampling procedure and participation rates for all five examinations ... important role in the aetiology of asthma and that these hormones are influenced by obesity. Direct effects of regurgitation due to abdominal obesity and inflammatory effects on the bronchioles ... and spirometry. Table 1. Background characteristics of the original cohort born in 1930 and the status of the subjects after 32 years Birth cohort 1930 Age in 1968-1969 38 Age if alive in...
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