Báo cáo y học: " Chemokine blockade: a new era in the treatment of rheumatoid arthritis" ppsx

... these molecules in normal homeostasis. Review Chemokine blockade: a new era in the treatment of rheumatoid arthritis? Jasper J Haringman and Paul P Tak Division of Clinical Immunology and Rheumatology, Academic ... migration selectively [20]. In that study a highly specific neutralizing antibody against IL-8 was administered in several types of acute inflammato...

Ngày tải lên: 09/08/2014, 01:23

... MC and LT were particularly involved in data collection and data analysis. All authors were involved in the interpretation of the data. All the authors have been involved in drafting and revising ... approach in quantitative psychiatry Annals of General Psychiatry 2010, 9:25 Cocchi et al. Annals of General Psychiatry 2010, 9:25 http://www.annals-general-psychiatry.com/con...

Ngày tải lên: 08/08/2014, 23:21

... Journal of Mathematical Analysis and Applications, vol. 233, no. 2, pp. 476–483, 1999. 6 A. N. Shiryayev, Probability, vol. 95 of Graduate Texts in Mathematics, Springer, New York, NY, USA, 1984. 7 ... urrmeyer-B ´ ezier operators D n,α are an important approximation operator of new type, the purpose of this paper is to continue studying the approximation properties of...

Ngày tải lên: 22/06/2014, 02:20

... P Maksymowych Department of Medicine, University of Alberta, Edmonton, Alberta T6G 2S2 Canada Corresponding author: Walter P Maksymowych, walter.maksymowych@ualberta.ca See related research article ... biomarkers may clarify our understanding of the pathophysiology of disease. Unlike rheumatoid arthritis, there is still no formal proof that inflammation is necessarily asso- ciated...

Ngày tải lên: 09/08/2014, 01:22

... possibility that the generalised vasculopathy of SScl may also be modifiable. In the characteristic microangiopathy of SScl, luminal narrowing results from a combination of intimal proliferation, medial ... therapy for PAH increases the importance of diagnosis and monitoring of this complication. Furthermore, since many principles of PAH management translate to the man...

Ngày tải lên: 09/08/2014, 06:23

... in hMLN51, 5'-TAATACGACTCACTATAGGGTACTCGTAA- GATGGCGGACCGG-3' and 5'-TAATACGACTCACTAT- AGGGTCCGTCCCCACTTTGCCTC-3', and in mMLN51, 5'- TAATACGACTCACTATAGGGTACTCGTAAGATGGCG- GACCGG-3' ... important in the proliferation of RA FLSs in the pathogenesis of RA. Introduction Synovial tissue from healthy individuals consists of a single layer of syno...

Ngày tải lên: 09/08/2014, 08:23

... and thereby the cata- bolic potential of the culture [6]. Gelatinase activity at 7, 11, and 17 days after catabolic treatment was compared with gelatinase activity after 7 days of IGF treatment, ... peptides are generated by an array of MMPs, of which MMP-2 and MMP-9 are only a subset. On other occasions, the presence of these gelatinases has been a valid indication of...

Ngày tải lên: 09/08/2014, 10:23

... CIA and early EAE. Autoim- mune inflammation in both the joint and brain is associated with the generation of citrullinated polypeptides that probably further induce epitope spreading of ACPA ... using myelin and synovial antigen arraysCharacterisation of antibody responses in collagen-induced arthritis (CIA) and experimental autoimmune encephalomyelitis (EAE) using myelin and...

Ngày tải lên: 09/08/2014, 13:22

... this article. MR was involved in data acquisition, interpretation of the data and cri- tiquing of drafts of this article. HF was involved in the analysis of data from this study and interpretation ... analysis, interpretation of the data, and critiquing of drafts of this article. BB was involved in the design of this project, analysis and interpreta- tion of t...

Ngày tải lên: 09/08/2014, 14:20

... Korea. Currently, IT-1 is being used under the name of the autoimmune target (AIT) test and it participates in the quality control program run by the Korean Society of Laboratory Medicine [3]. In 1999 and ... was a form of HEp-2 cell that was transfected with cDNA encoding human Ro60. A human macrophage cell line called the IT-1 cell line was first introduced at the...

Ngày tải lên: 09/08/2014, 14:21