Báo cáo y học: "Decreased levels of soluble amyloid β-protein precursor and β-amyloid protein in cerebrospinal fluid of patients with systemic lupus erythematosus" ppsx

... 1 Decreased levels of soluble amyloid β -protein precursor and β -amyloid protein but increases of intrathecal axonal degradation products and TGF-β in patients with cerebral lupus. (a) Cerebrospinal fluid ... P, Lin WM, Yu HS, Yu CL: Cerebrospinal fluid interleukin-6, prostaglandin E2 and autoantibodies in patients with neuropsychiatric systemic...

Ngày tải lên: 09/08/2014, 01:23

... (4 patients) , cyclosporine A (5 patients: 2 in combination with MTX, 1 in combination with leflunomide, 1 in combination with azathio- prine, and 1 with sulfasalazine), and azathioprine (2 patients) . Nine ... Vitamin D binding protein (Gc-globulin). Endocr Rev 1989, 10:294-307. 18. Lind SE, Smith DB, Janmey PA, Stossel TP: Role of plasma gel- solin and the vitamin...

Ngày tải lên: 09/08/2014, 13:22

... TGFβ stimulated repair of IL-1- and OA-damaged cartilage. TGFβ- induced synovial fibrosis was blocked by locally inhibiting TGFβ signaling in the synovial lining by simultaneously transfecting it with an adenovirus ... damage by injection of interleukin-1 (IL-1) into murine knee joints. After 2 days, we injected an adenovirus encoding TGFβ. On day 4, we measured proteoglycan (PG) sy...

Ngày tải lên: 09/08/2014, 07:20

... of lym- phocytes that originally were regarded to play crucial roles in protection from infectious disease and destroying tumour cells; they are also involved in certain autoimmune diseases and ... proliferation in the presence of cytokinesCytotoxicity of NK cells after ex vivo proliferation in the presence of cytokines. (a) Cytotoxicity of natural killer (NK) cells to...

Ngày tải lên: 09/08/2014, 10:22

... isolated in community-acquired pneumonia is increasingly found in primary pyogenic liver abscesses. The presence of magA in K. pneumoniae has been impli- cated in hypermucoviscosity and virulence of ... the fluoroquinolones (ciprofloxacin, levofloxacin), the aminoglycosides (amikacin, gentamicin, and tobra- mycin), meropenem, pipercillin/tazobactam and trimethoprim/sulfa...

Ngày tải lên: 26/10/2012, 09:53

... pathways of both MAPK (ERK, p38 and JNK) and IκB kinase within 30 min, with pathway activation subsiding to the basal levels of nonstimu- lated cells by 60 min. The activation of these pathways ... mobility shift assay The protein- DNA binding activity in nuclear factor-κB (NF-κB) was determined using electrophoretic mobility shift assay (EMSA). In brief, 10 μg nuclear pro...

Ngày tải lên: 09/08/2014, 10:20

... measurement of serum thrombopoietin and expression of megakaryocyte c-mlp with clinical and laboratory correlates for myelofibrosis with myeloid metaplasia. Eur J Haematol 2002;68:175-9. 27. Yan ... Lacey D, Hill D, Chen Y, Fletcher F, Hawley RG, McNiece IK A model of myelofibrosis and osteosclerosis in mice induced by overexpressing thrombopoietin (mpl ligand): rev...

Ngày tải lên: 03/11/2012, 10:52

... these proteins may be co-regulated in RA. This is supported by a previous study of S100 proteins in RA patients [58], and is in keeping with the high S100 gene expression profiles reported in RA ... associated with serum levels of C-reactive protein (CRP) and high-density lipoprotein (HDL), history of vasculitis, and the presence of the RAGE 82Ser polymorphism....

Ngày tải lên: 09/08/2014, 13:22

... selenocysteine-containing antioxidant enzyme that reacts with hydrogen peroxide and soluble fatty acid hydroperoxides, thereby helping to maintain redox balance within cells. Serum levels of GPX3 ... can- cer risk in women with an ovarian mass [11]. Interestingly, levels of three of the five biomarkers, apolipoprotein, pre- albumin and transferrin, decrease in women w...

Ngày tải lên: 20/06/2014, 08:20

... fully understood. In the present study we examined the central and effector memory phenotypes of CD4 + and CD8 + T cells in the peripheral blood of patients with RA and systemic lupus erythematosus. Terminally ... increased recruitment into the inflamed synovium in RA. Inflammation and production of chemokines such as macrophage inflammatory protein- 1α and RANT...

Ngày tải lên: 09/08/2014, 01:21