Báo cáo y học: "Citrullination, a possible functional link between susceptibility genes and rheumatoid arthritis" ppsx

... Sawada T, Suzuki M, Nagasaki M, Nakayama-Hamada M, Kawaida R, Ono M, Ohtsuki M, Furukawa H, Yoshino S, Yukioka M, Tohma S, Matsubara T, Wakitani S, Teshima R, Nishioka Y, Sekine A, Iida A, Takahashi ... enzyme are associated with RA. Commentary Citrullination, a possible functional link between susceptibility genes and rheumatoid arthritis Erik R Vossenaar, Albert JW Zend...

Ngày tải lên: 09/08/2014, 01:23

... Hardy-Weinberg equilibrium [see Tables S11 and S12 in Additional data file 1]. Additionally, we carried out a subset analysis of RA samples stratified to RF status. Association between RA and HLA- DRB1 ... analysis and drafted the manuscript. JR and SB collected the sample and phenotyped the patients. HGW and SF carried out the HLA typing. CH participated in study coordination...

Ngày tải lên: 09/08/2014, 14:20

... citation purposes) 20. Kawanaka N, Yamamura M, Aita T, Morita Y, Okamoto A, Kawashima M, Iwahashi M, Ueno A, Ohmoto Y, Makino H: CD14+, CD16+ blood monocytes and joint inflammation in rheumatoid arthritis. ... mo NSAID 5 Early RA RA + M/40 11 mo None 6 Early RA RA + M/54 11 mo None 7 Early RA RA + F/62 10 mo NSAID 8 Early RA RA + M/75 18 mo NSAID 9 Early RA RA + M/82 12 mo NSAID 10 E...

Ngày tải lên: 09/08/2014, 10:20

... Inc., Santa Clara, California, USA). The 260:280 ratios were typically greater than 2.2 and absence of degradation was evidenced by sharp 18 s and 28 s bands. Equal amounts of total RNA from each ... and made major contributions at all stages of manuscript preparation. HO, SA, JMC, and PvD performed statistical analyses. Additional data files The following additional data files are av...

Ngày tải lên: 09/08/2014, 20:20

... Adh 5a and Adh5b genes reside between Adh1 and Adh2 ind icating an overall order of Adh4-Adh1 -Adh 5a- Adh5b-Adh5ps-Adh2- Adh3. The mouse Adh 5a and Adh5b reside in the same relative position as the ... than 90% similarity. The enzyme class names and g en e names now corre- spond. The class II human and mouse enzymes are encoded by ADH2 and Adh2, r espectively; class III enz...

Ngày tải lên: 08/03/2014, 16:20

... were coded and evaluated blindly by two investigators with respect to synovial hypertrophy, to the inflammatory cell infiltration of the synovia, to pannus formation, and to carti- lage and subchondrial ... HGF-mediated release of inflammatory cytokines (IL-6 and granulocyte–macrophage colony-stimulating factor) by human monocytes [34]. The uPA-induced arthritis may be mediated, besid...

Ngày tải lên: 09/08/2014, 01:21

... arms and legs 2.5 Yes None Yes None Recovery 8 53 m RA L No Erythema nodosum Painful erythematou s nodules Lower legs 7.4 Yes AZA, naproxen, paracetamol No Topical Partial recovery a A, ... JT, Tannenbaum H, Hua Y, Teoh LS, Fischkoff SA, Chartash EK: Radiographic, clinical, and functional outcomes of treatment with adalimumab (a human anti-tumor necrosis factor monoclonal an...

Ngày tải lên: 09/08/2014, 06:22

... G, Barrett E, Silman A, Symmons D: Associations between demographic and disease-related variables and dis- ability over the first five years of inflammatory polyarthritis: a longitudinal analysis ... baseline and three years, 3.9 points/year between three and five years, and 3.62 points/year between five and 10 years. Predictive factors of radiographic outcome In univaria...

Ngày tải lên: 09/08/2014, 13:21

... of 13 are examples of metadata) - to repeat an analysis exactly. When a user performs an analysis using Galaxy, it automatically generates metadata for each analysis step. Galaxy’s metadata includes ... tagging and annotations are integrated into Galaxy’ s analysis workspace and are designed to support web-based genomic research. Galaxy tags are hierarchical and can have values, and...

Ngày tải lên: 09/08/2014, 20:22

... Ohtsuki M, Furukawa H, Yoshino S, Yukioka M, Tohma S, Matsubara T, Wakitani S, Teshima R, Nishioka Y, Sekine A, Iida A, Takahashi A, Tsunoda T, Nakamura Y, Yamamoto K: Functional haplotypes of PADI4, encoding ... forms of the alpha- and beta-chains of fibrin. J Immunol 2001, 166:4177-4184. 27. Suzuki A, Yamada R, Chang X, Tokuhiro S, Sawada T, Suzuki M, Nagasaki M, Nakayama-Hamada...

Ngày tải lên: 09/08/2014, 01:23