Báo cáo y học: "Autoimmune response in cartilage-delivered peptides in a patient with osteoarthritis" pptx

... Tsuruha J, Masuko-Hongo K, Kato T, Sakata M, Nakamura H, Nishioka K: Implication of cartilage intermediate layer protein in cartilage destruction in subsets of patients with osteoarthritis and ... immunomodulative agent. Competing interests None declared. References 1. Nakamura H, Yoshino S, Kato T, Tsuruha J, Nishioka K: T-cell mediated inflammatory pathway in osteoarthritis. Osteoar...

Ngày tải lên: 09/08/2014, 01:23

... Martínez Lacasa J, Salavert M, Vidal R, Rodríguez Carballeira M, Garau J: Paradoxical response to antituberculous therapy in infliximab-treated patients with disseminated tuberculosis. Clin Infect ... to complaints of pain and purulent discharge from a fistula. Histologic examination of the lymph node samples revealed chronic caseating granulomatous inflammation, but the AFB staining...

Ngày tải lên: 11/08/2014, 17:21

... cells Downstream signal transduction pathways were analyzed by studying the activation level of JAK/STAT and MAP kinase signaling components known to be mainly tyrosine phosphorylated in response ... CNTF (even at high concentrations) alone were able to activate the MAPK pathway. MAP kinases and STAT3 are rapidly activated within 10 min in response to Hyper-CNTF, the phase of activati...

Ngày tải lên: 22/02/2014, 07:20

... “French-Canadian AID mutation.” The patient was referred to our clinic at the age of 16 years. He had had chronic cervical lym- phadenopathy since the age of 2 years and also had recurrent sinopulmonary ... Editor: We have diagnosed a patient from Quebec with hyperimmunoglobulin M (hyper-IgM) syndrome resulting from a defect in activation-induced cyti- dine deaminase (AID). The...

Ngày tải lên: 08/08/2014, 21:20

... lack the PSR only in certain tissue) promises to be an even more fascinating and exciting story, which may shed new lights into the anti-inflammatory signalling pathways that are implicated in ... lung and brain, and it may play a key role in controlling inflammatory events in these organs. Nevertheless, dissecting the PSR-mediated pathways in viable conditional knockout animals (...

Ngày tải lên: 09/08/2014, 01:23

... main cytokine involved in cartilage degradation, when it was injected intra-articularly into OA knees. These unexpected negative results raise several points. First, reality does not always match ... theory. Many biological pathways remain to be discovered, although they may be critical because they interact with a potential drug Editorial The quest for the Holy Grail: a disease-modif...

Ngày tải lên: 09/08/2014, 10:22

... possible pacing site. We placed an atrial lead at the right appendage and a RV lead at the apex. A LV lead was placed at the lateral wall of the coronary sinus because there was the possibility that the ... 10.1186/1749-8090-5-47 Cite this article as: Mima et al., Effective cardiac resynchronization therapy for an adolescent patient with dilated cardiomyopathy seven years after mitr...

Ngày tải lên: 10/08/2014, 09:22

... antibodies and a higher prevalence of Raynaud’s phenomenon and dysphagia compared to ACA-/SS patients. They also had lower prevalence of telangiectasias, puffy fingers, sclerodactyly, Raynaud’s phenomenon, ... patients was 3.7%. Cases and controls did not differ in sex ratio and age at disease onset. ACA+/SS patients had a lower prevalence of dry eyes, hypergammaglobulinaemia, anti-Ro a...

Ngày tải lên: 12/08/2014, 12:20

... complexity of chronic airway inflammation and remodelling in asthma, even if the activity of allergy-related airway inflammation is known. In this study, responses to salbutamol are better correlated ... and bronchodilator response in airways. In our patients with allergic asthma, FEV 1 increased by 18.39% after salbutamol inhalation, whereas after ipra- tropium, FEV 1 increased b...

Ngày tải lên: 08/08/2014, 21:20

... Morita Y, Yamamura M, Kawashima M, Harada S, Tsuji K, Shibuya K, Maruyama K, Makino H: Flow cytometric single-cell analysis of cytokine production by CD4+ T cells in synovial tissue and peripheral ... the IFN-γ-dominant T-cell cytokine response in joints of patients with long- standing RA [13]. IL-18 is a proinflammatory cytokine that plays an important role in the Th1-type immun...

Ngày tải lên: 09/08/2014, 01:23